Abstract: A CT system includes a gantry, an x-ray source, a detector, and a grating collimator that includes alternating first and second materials. The system includes a controller configured to emit a first beam of x-rays from a first focal spot and to a first detector pixel, wherein the first beam of x-rays passes along a ray and through one of the first materials of the grating collimator, and subsequently emit a second beam of x-rays from a second focal spot and to the first detector pixel, wherein the second beam of x-rays passes substantially along the ray and through one of the second materials of the grating collimator. The system includes a computer programmed to generate first and second kVp image datasets using data acquired from the first beam and second beams of x-rays, and reconstruct a basis material image of the object.

Abstract: A method for correcting Positron Emission Tomography (PET) data includes adjusting a tube current generated by the CT imaging system to a second tube current value that is less than a first tube current value used to generate diagnostic quality CT images, and imaging the patient with the CT imaging system set at the second tube current value. The method also includes generating a plurality of computed tomography (CT) projection data from the CT imaging system and preprocessing the CT projection data to generate preprocessed CT projection data. The method further includes filtering the preprocessed CT projection data to reduce electronic noise to generate filtered CT projection data, and performing a minus logarithmic operation on the filtered CT projection data to generate the corrected PET data.

Abstract: A method includes fitting a motion map from a first imaging modality with a first FOV to a second imaging modality different from the first with a second FOV sized differently than the first FOV.

Abstract: A CT system includes a gantry, an x-ray source configured to project x-rays toward an object, an x-ray detector positioned to receive x-rays from the x-ray source that pass through the object, a generator configured to energize the x-ray source to a first voltage and to a second voltage that is distinct from the first voltage, and a controller configured to cause the gantry to position the source and generator at a circumferential position during an imaging session, pass the object through the opening during the imaging session, cause the generator to energize the x-ray source to the first voltage and to the second voltage, acquire imaging data while the generator energizes the x-ray source to the first voltage and to the second voltage while the rotatable gantry is at the circumferential position, and generate an image using the imaging data.

Abstract: A method and system for controlling image reconstruction in an imaging system are provided. The method includes receiving scan data from an imaging system, and determining regularization parameters for a plurality of portions of an image for reconstructing the image based on the received scan data, wherein the regularization parameters vary for the plurality of portions of the image.

Abstract: A computerized tomographic system configured to acquire short scan data of an object within a single revolution of a detector array about the object over a first angular range of rotation of the detector array about the object, define a temporal subset of the acquired short scan data over a second angular range of rotation of the detector that is less than the first angular range of rotation, generate a mathematical function that is based on the acquired short scan data and the defined temporal subset of data, minimize the mathematical function, and generate an image of the object using the minimized mathematical function and the data acquired over the second angular range of rotation of the detector.

Abstract: A method for reconstructing images of structures undergoing physiological motion comprises acquiring a first volume of data over a first motion cycle. The first volume comprises a first overlap volume. A second volume of data is acquired over a second motion cycle and comprises a second overlap volume. The first and second overlap volumes comprise like anatomical regions with respect to each other. A reconstructed volume of data is formed based on temporal data within the first and second overlap volumes.

Abstract: Approaches for deriving scatter information using inverse tracking of scattered X-rays is disclosed. In certain embodiments scattered rays are tracked from respective locations on a detector to a source of the X-ray radiation, as opposed to tracking schemes that proceed from the source to the detector. In one such approach, the inverse tracking is implemented using a density integrated volume that reduces the integration steps performed.

Abstract: Estimation of blood flow parameters using non-invasive imaging techniques is described. In one implementation, temporally distinct image volumes are generated. Each respective image volume depicts a respective spatial distribution of a contrast agent within an imaged volume at a different time. The contrast agent movement at each different time from the plurality of image volumes is used in the estimation of a parameter related to the flow of blood within the imaged volume.

Abstract: A method for reconstructing an image of an object includes acquiring a set of measured projection data, reconstructing the measured projection data using a first algorithm to generate a first reconstructed image dataset, reconstructing the measured projection data using a second algorithm to generate a second reconstructed image dataset, the second algorithm being utilized to improve the temporal resolution of the second reconstructed image dataset, and generating a final image dataset using both the first and second image datasets.

Abstract: A method for reconstructing an image of an object includes scanning an object using a computed tomographic (CT) imaging apparatus to acquire projections of the object. A set of thresholds are determined utilizing the projections, and selected smoothing kernels are associated with the thresholds. The method further includes utilizing the smoothing kernels and the projections to produce smoothed projections in accordance with the thresholds and filtering and backprojecting the smoothed projections to generate an image of the object.

Abstract: A method for reconstructing an image of an object includes performing an air calibration on an imaging system to generate set of air calibration data, estimating an x-ray spectrum using the air calibration data, and reconstructing an image of an object using the estimated x-ray spectrum. An imaging system and a non-transitory computer readable medium are also described herein.

Abstract: Methods and apparatus for statistical iterative reconstruction are provided. One method includes pre-processing acquired raw measurement data to modify the raw data measurement data and determining a change in a variance of the raw measurement data resulting from the modification to the raw measurement data during pre-processing. The method also includes reconstructing an image using the modified raw measurement data resulting from the pre-processing and the determined change in variance.

Abstract: A method for reconstructing an image of an object that includes a plurality of image elements. The method includes accessing image data associated with a plurality of image elements, and reconstructing an image of the object by optimizing an objective function, where the objective function is optimized by iteratively solving a nested sequence of approximate optimization problems. The algorithm is composed of nested iterative loops, in which an inner loop iteratively optimizes an objective function approximating the outer loop objective function, and an outer loop that utilizes the solution of the inner loop to optimize the original objective function.

Abstract: A method is provided that includes acquiring a first set of image data from X-rays produced at a first energy level and a second set of image data from X-rays produced at a second energy level. The method includes generating a first noise mask for a first basis material and a second noise mask for a second basis material and removing pixels corresponding to cross contaminating structural information from the first noise mask and the second noise mask. The method includes processing a first materially decomposed image generated from the first set of image data and the second set of digital data using the second noise mask after removal of the cross contaminating structural information and processing a second MD image generated from the first set of image data and the second set of digital data using the first noise mask after removal of the cross contaminating structural information.

Abstract: A CT system includes an x-ray source configured to project an x-ray beam toward an object, a detector array, and a bowtie filter. The bowtie filter includes a first x-ray filtration region positioned to attenuate x-rays that pass through an isochannel of the detector array, a second x-ray filtration region positioned to attenuate x-rays that pass through channels of the detector array that are offcenter in a channel direction from the isochannel, and an x-ray attenuation material positionable to attenuate the x-rays that pass through the channels of the detector array that are offcenter in the channel direction from the isochannel. The CT system also includes a data acquisition system (DAS) connected to the detector array and configured to receive outputs from the detector array, and a computer programmed to acquire projections of imaging data of the object, and generate an image of the object using the imaging data.

Abstract: A CT system includes a rotatable gantry having an opening to receive an object to be scanned, an x-ray source configured to project an x-ray beam toward the object having a primary intensity, a detector configured to detect high frequency electromagnetic energy passing through the object and output imaging data, and a data acquisition system (DAS) connected to the detector and configured to receive the imaging data. The system also includes a computer programmed to obtain image projection data of the object from the DAS, correct the projection data using a scatter function that is based at least on a known characteristic of the x-ray beam, and generate images using the corrected projection data.

Abstract: A collimator for an imaging system includes a first region comprising a first one-dimensional array of apertures along a channel direction, and a second region comprising a second one-dimensional array of apertures along the channel direction, wherein an aspect ratio of the apertures of the first region is greater than an aspect ratio of the second region.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller. The controller is configured to apply a first kVp for a first time period, apply a second kVp for a second time period, integrate two or more view datasets during the first time period, integrate one or more view datasets during the second time period, and generate an image using the datasets integrated during the first time period and during the second time period.

Abstract: A CT system includes a generator configured to energize an x-ray source to a first kilovoltage (kVp) and to a second kVp, and a computer that is programmed to acquire a first view dataset with the x-ray source energized to the first kVp and a second view dataset with the x-ray source energized to the second kVp, generate a base correction image using the first view dataset and the second view dataset, and reconstruct a pair of base material images from the first view dataset and from the second view dataset. The computer is also programmed to estimate artifact correlation in the pair of base material images using the base correction image, generate a pair of final base material images and a final monochromatic image, and correct one of the pair of final base material images and the final monochromatic image at a keV value using the estimated artifact correlation.