Abstract: The present invention relates to a multi-layer coupling relationship-based train operation deviation propagation condition recognition method, where the method includes the following steps: (1) recognizing an effective train event time sequence, including an arrival event and a departure event of a train at each passing station; (2) uniformly extracting train activity data, including a stop activity, a section operation activity, a turn-back activity, and an arrival or departure interval activity; (3) constructing coupling relationship groups between a train event and a train activity and between train activities; and (4) performing statistics on changes of train operation deviation in each relationship group, and outputting a respective distribution function and a time-space distribution visualized result. Compared with the prior art, the present invention has the advantages of being practical, automatic recognition, feedback optimization, and the like.

Abstract: Biomarkers to screen for, identify, and/or characterize lung cancer in a subject are disclosed. Also disclosed herein are methods for distinguishing lung cancer from another disease. Also disclosed herein are methods for detecting metastasis of a lung cancer in a subject. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.

Abstract: A sliding sleeve device has an outer cylinder, a circulation hole being provided in the wall of the outer cylinder; and an inner cylinder provided in an inner cavity of the outer cylinder. In an initial state, the inner cylinder and the outer cylinder are fixed to each other to seal the circulation hole. In a first state, the inner cylinder is movable relative to the outer cylinder, thereby unsealing the circulation hole. A protection mechanism is provided in the circulation hole, which has an inner member located on the radially inner side and an outer member located on the radially outer side.

Abstract: Provide is a novel mixed-noise removal method for HSI with large size. First, the underlying structure of the HSI is modeled by a two-layer architecture graph. The upper layer, called a skeleton graph, is a rough graph constructed by using the modified k-nearest-neighborhood algorithm and its nodes correspond to a series of superpixels formed by HSI segmentation, which can efficiently characterize the inter-correlations between superpixels, while preserving the boundary information and reducing the computational complexity. The lower layer, called detailed graph, consists of a series of local graphs which are constructed to model the similarities between pixels. Second, based on the two-layer graph architecture, the HSI restoration problem is formulated as a series of optimization problems each of which resides on a subgraph. Third, a novel distributed algorithm is tailored for the restoration problem, by using the information interaction between the nodes of skeleton graph and subgraphs.

Abstract: A new sliding sleeve relates to the technical field of oil and gas well completion and reservoir stimulation, comprising an upper connector, a lower connector, an outer housing, an inner sleeve and a shear pin. The upper connector and the lower connector are respectively connected to two ends of the outer housing, and the inner sleeve is locked in the outer housing via the shear pin, wherein a flow guiding hole is provided in the outer housing, and the inner sleeve can open or close the flow guiding hole, wherein at least two grooves for engaging with at least two corresponding tooth-shaped elements on a sliding sleeve opening tool are disposed along an axial direction in the inner sleeve, and wherein an erosion-resistant ring is embedded in the groove, and an inner diameter of the erosion-resistant ring is larger than or equal to an inner diameter of the inner sleeve.

Abstract: PDCs, methods of fabricating the PDCs, and methods of using the PDCs are disclosed herein. The PDCs include a PCD table bonded to a substrate. The PCD table includes an upper surface having a plurality of recessed features formed therein. The plurality of recessed features are configured to attract at least some cracks that form in the PCD table. As such, the plurality of recessed features limit or prevent crack propagation into other portions of the PCD table and limit a volume of the PCD table that spalls. Methods of fabricating the PDCs include partially leaching the PCD table and, after leaching the PCD table, forming the plurality of recessed features in the upper surface thereof. Method of using the PDCs include rotating a PDC that has spalled relative to a rotary drill bit such that a portion of the upper surface of the PDC that has not spalled forms a cutting surface thereof.

Abstract: A sliding sleeve device has an outer cylinder, a circulation hole being provided in the wall of the outer cylinder; and an inner cylinder provided in an inner cavity of the outer cylinder. In an initial state, the inner cylinder and the outer cylinder are fixed to each other to seal the circulation hole. In a first state, the inner cylinder is movable relative to the outer cylinder, thereby unsealing the circulation hole. A protection mechanism is provided in the circulation hole, which has an inner member located on the radially inner side and an outer member located on the radially outer side.

Abstract: The invention relates to an operation diagram-based method for automatically changing a route to turn back in case of interruption. The method obtains an alternative turn-back point according to the position of a fault point and the information of a line turn-back station, calculates a corresponding turn-back plan of the alternative turn-back point according to an operation diagram of the current day, and finally automatically changes an online train route according to the new turn-back plan, so as to realize automatic turn-back of a train after route adjustment in case of interruption. Compared with the prior art, the method has the advantage of being able to keep the compatibility with an existing operation diagram while quickly changing a route in case of partial line interruption, so as to facilitate quick recovery of planned operation after a fault is removed.

Abstract: The present disclosure provides methods for generating retinal cell clusters for use in cellular component transfer therapy, retinal cell clusters generated by such methods, and compositions comprising such retinal cell clusters. The present disclosure also provides uses of the retinal cell clusters and compositions comprising thereof for preventing and/or treating inherited retinal degenerative diseases.

Abstract: The present disclosure relates to a system and method for automatic adjustment of a planned train operation chart. The system comprises a train operation data analysis module, a passenger flow data matching module, and an operation chart adjustment module that are connected in sequence. The train operation data analysis module is connected to the operation chart adjustment module; the train operation data analysis module assesses the deviation between an actual operation chart and a planned operation chart on the basis of ATS historical operation data to obtain an operation chart assessment result; the passenger flow data matching module calculates the actual passenger flow distribution on the basis of on-board weighing passenger flow data and AFC passenger flow data, and matches the actual passenger flow distribution with the actual operation chart to obtain a passenger flow matching result; and the operation chart adjustment module performs optimizing adjustment.

Abstract: A noise suppression method and system for Inverse Synthetic Aperture Radar micro-cluster objects using a generative adversarial network (GAN) are provided. The method includes: constructing the GAN, including a generator and a discriminator; obtaining and inputting noisy simulation data into the generator to obtain a first output, comparing the first output with noiseless simulation data to obtain a first generator loss, inputting the first output and the distribution function into the discriminator for denoising discrimination to obtain a first discriminant result, and determining a second generator loss according to the first generator loss and the first discriminate result; and obtaining measured data and inputting the measured data into the generator to obtain a second output, inputting the second output to the discriminator to obtain a second discriminant result, and determining a generator loss according to the second generator and the second discriminate result.

Abstract: A method of constructing a bounding box comprises: acquiring a set of sensed data points; adding, for each sensed data point, at least one calculated data point; and defining a bounding box containing the sensed and calculated data points. A method of identifying voxels in a voxel grid corresponding to a plurality of data points comprises: calculating, for each data point, a distance between it and each voxel; creating a subset of voxels comprising voxels having a distance from one data point that is less than a predetermined distance; creating another subset comprising those voxels that neighbor a voxel in the first subset; computing, for each voxel in the second subset, a distance between it and each voxel in the first subset; and identifying each voxel in the first subset that is a distance away from each voxel in the second subset that exceeds a predetermined distance.

Abstract: The present invention relates to a multi-layer coupling relationship-based train operation deviation propagation condition recognition method, where the method includes the following steps: (1) recognizing an effective train event time sequence, including an arrival event and a departure event of a train at each passing station; (2) uniformly extracting train activity data, including a stop activity, a section operation activity, a turn-back activity, and an arrival or departure interval activity; (3) constructing coupling relationship groups between a train event and a train activity and between train activities; and (4) performing statistics on changes of train operation deviation in each relationship group, and outputting a respective distribution function and a time-space distribution visualized result. Compared with the prior art, the present invention has the advantages of being practical, automatic recognition, feedback optimization, and the like.

Abstract: The present invention relates to a full-day in each train operation diagram generation method based on a time division scheme and an activity-event relationship, the method including: S1: configuring operation scheme basic parameters; S2: constructing a quantitative relationship between a travel time and a driving interval for different routing ratios and calculating, within a given turn-back time range, an actual turn-back time of each turn-back station that can achieve a routing ratio requirement; S3: generating an arrival event time and a departure event time of a train in each time period at a station platform in accordance with routing division, direction division, and proportion division, correcting a start time and a stop time of each routing in accordance with time period division, and performing transition between the time periods; and S4: connecting a train section operation activity and a stop activity according to the full-time train arrival and departure event times obtained by executing step S3

Abstract: A method of constructing a bounding box comprises: acquiring a set of sensed data points; adding, for each sensed data point, at least one calculated data point; and defining a bounding box containing the sensed and calculated data points. A method of identifying voxels in a voxel grid corresponding to a plurality of data points comprises: calculating, for each data point, a distance between it and each voxel; creating a subset of voxels comprising voxels having a distance from one data point that is less than a predetermined distance; creating another subset comprising those voxels that neighbor a voxel in the first subset; computing, for each voxel in the second subset, a distance between it and each voxel in the first subset; and identifying each voxel in the first subset that is a distance away from each voxel in the second subset that exceeds a predetermined distance.

Abstract: Biomarkers to screen for, identify, and/or characterize lung cancer in a subject with high selectivity and high specificity are disclosed. Also disclosed herein are methods for distinguishing lung cancer from another disease. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.

Abstract: A method for constructing a data processing model, includes: acquiring a model description parameter and sample data of a target data processing model; determining a base model according to the model description parameter and the sample data; and training the base model according to the sample data to obtain the target data processing model.

Abstract: A method of constructing a bounding box comprises: acquiring a set of sensed data points; adding, for each sensed data point, at least one calculated data point; and defining a bounding box containing the sensed and calculated data points. A method of identifying voxels in a voxel grid corresponding to a plurality of data points comprises: calculating, for each data point, a distance between it and each voxel; creating a subset of voxels comprising voxels having a distance from one data point that is less than a predetermined distance; creating another subset comprising those voxels that neighbor a voxel in the first subset; computing, for each voxel in the second subset, a distance between it and each voxel in the first subset; and identifying each voxel in the first subset that is a distance away from each voxel in the second subset that exceeds a predetermined distance.

Abstract: A highly integrated, fully automatic chemiluminescence detection equipment and its operation method are disclosed. The chemiluminescence detection equipment comprises a control module, a first electrical machine, a reagent wheel disc tank, a sampling module, a washing module, a second electrical machine and a detection module. Compared with the traditional large-scale chemiluminescence detection equipment, the chemiluminescence detection equipment of the present invention has the advantage of high integration, and greatly reduces the overall volume and weight of the chemiluminescence detection equipment.

Abstract: In an embodiment, a method of fabricating a polycrystalline diamond compact is disclosed. The method includes sintering a plurality of diamond particles in the presence of a metal-solvent catalyst to form a polycrystalline diamond body; leaching the polycrystalline diamond body to at least partially remove the metal-solvent catalyst therefrom, thereby forming an at least partially leached polycrystalline diamond body; and subjecting an assembly of the at least partially leached polycrystalline diamond body and a cemented carbide substrate to a high-pressure/high-temperature process at a pressure to infiltrate the at least partially leached polycrystalline diamond body with an infiltrant. The pressure of the high-pressure/high-temperature process is less than that employed in the act of sintering of the plurality of diamond particles.