Patents by Inventor Jiangbin Ye

Jiangbin Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sensitization of cancer cells to differentiation therapy with mitochondrial uncoupler niclosamide ethanolamine
    Patent number: 11918550
    Abstract: Methods are provided for the treatment of cancer by administering a mitochondrial uncoupler in a dose effective to increase differentiation of the cancer cells, which may be provided in a combination with a retinoic acid to differentiate the cancer cells. The effect on the targeted cancer cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used. The cancer may be resistant to retinoic acid.
    Type: Grant
    Filed: December 3, 2021
    Date of Patent: March 5, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jiangbin Ye, Haowen Jiang, Yang Li
  • Treatment of cancer with combinations of agents
    Patent number: 11684601
    Abstract: Methods are provided for the treatment of cancer by administering a combination of metabolic interventions to differentiate the cancer cells. The effect on the targeted cancer cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: June 27, 2023
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jiangbin Ye, Yang Li
  • SENSITIZATION OF CANCER CELLS TO DIFFERENTIATION THERAPY WITH MITOCHONDRIAL UNCOUPLER NICLOSAMIDE ETHANOLAMINE
    Publication number: 20220175704
    Abstract: Methods are provided for the treatment of cancer by administering a mitochondrial uncoupler in a dose effective to increase differentiation of the cancer cells, which may be provided in a combination with a retinoic acid to differentiate the cancer cells. The effect on the targeted cancer cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used. The cancer may be resistant to retinoic acid.
    Type: Application
    Filed: December 3, 2021
    Publication date: June 9, 2022
    Inventors: Jiangbin Ye, Haowen Jiang, Yang Li
  • Dietary Supplements and Composition for Treating Cancer
    Publication number: 20220031646
    Abstract: Methods and compositions for treating cancer and other disorders associated with undesired cellular proliferation are provided comprising administering to a subject in need thereof an amino acid mixture, wherein the amino acid mixture comprises glycine, optionally comprising at least a 2:1 molar ratio of glycine to serine.
    Type: Application
    Filed: October 15, 2021
    Publication date: February 3, 2022
    Inventors: Joshua D. Rabinowitz, Craig B. Thompson, Jiangbin Ye, Jing Fan, Jurre Kamphorst
  • Dietary supplements and composition for treating cancer
    Patent number: 11147784
    Abstract: Methods and compositions for treating cancer and other disorders associated with undesired cellular proliferation are provided comprising administering to a subject in need thereof an amino acid mixture, wherein the amino acid mixture comprises glycine, optionally comprising at least a 2:1 molar ratio of glycine to serine.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: October 19, 2021
    Assignees: THE TRUSTEES OF PRINCETON UNIVERSITY, MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Joshua D. Rabinowitz, Craig B. Thompson, Jiangbin Ye, Jing Fan, Jurre Kamphorst
  • TREATMENT OF CANCER WITH COMBINATIONS OF AGENTS
    Publication number: 20200261393
    Abstract: Methods are provided for the treatment of cancer by administering a combination of metabolic interventions to differentiate the cancer cells. The effect on the targeted cancer cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used.
    Type: Application
    Filed: February 14, 2020
    Publication date: August 20, 2020
    Inventors: Jiangbin Ye, Yang Li
  • Dietary Supplements and Composition for Treating Cancer
    Publication number: 20190209503
    Abstract: Methods and compositions for treating cancer and other disorders associated with undesired cellular proliferation are provided comprising administering to a subject in need thereof an amino acid mixture, wherein the amino acid mixture comprises glycine, optionally comprising at least a 2:1 molar ratio of glycine to serine.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 11, 2019
    Inventors: Joshua D. Rabinowitz, Craig B. Thompson, Jiangbin Ye, Jing Fan, Jurre Kamphorst