Patents by Inventor Jianguo LU
Jianguo LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240099972Abstract: The present disclosure relates to a method to improve the encapsulation efficiency and physicochemical stability of ginsenosides Rg3 and CK nano-emulsion, belonging to the field of functional emulsions. The method to improve the encapsulation efficiency and physicochemical stability of ginsenosides Rg3 and CK nano-emulsion, includes the following steps: (1) WPI, Tween 80 and water were mixed evenly according to the amount ratio of 0.5 g:0.5-0.7 g:50 mL to obtain the aqueous phase; (2) Mixing a saponin extract containing the minor ginsenosides Rg3 and CK with edible oil evenly to obtain the oil phase; (3) Mixing the aqueous phase with the oil phase, carrying out shearing dispersion to obtain coarse emulsion, and then allowing the coarse emulsion to be subjected to microfluidization homogenization to obtain an oil-in-water nano-emulsion containing the minor ginsenosides Rg3 and CK.Type: ApplicationFiled: December 1, 2023Publication date: March 28, 2024Inventors: Peng ZHOU, Changshu Liu, Yaowei Liu, Tao Yang, Yan Zheng, Jianguo Liu, Kexin Li, Shuyan Lu
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Patent number: 11911940Abstract: For in mold spraying, a double-inclined mixing nozzle is connected obliquely and fixedly with a side surface of a third half-mold through a lateral sealing structure and connected with a side surface of a first half-mold in an inclined and sealing manner, side faces of a first half-mold and the third half-mold are respectively provided with installation inclined surfaces. A lateral sealing structure includes a mounting plate and a sealing member. The sealing member is sleeved on the double-inclined mixing nozzle and is in transition fit with the double-inclined mixing nozzle and the mounting plate respectively. A butt sealing groove provided on the installation inclined surface of the first half-mold and is in sealing fit with the mounting plate.Type: GrantFiled: October 3, 2022Date of Patent: February 27, 2024Assignee: Tederic Machinery Co., Ltd.Inventors: Jianguo Zheng, Hongwei Zhou, Jiahui Lu, Haibo Shen, Wu Lin, Binqi Rao, Hongyuan Ma, Bo Liu, Guolin Liu, Jia Zhou
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Publication number: 20230270913Abstract: A medical polyurethane foam dressing and a preparation method thereof are provided in this disclosure. The medical polyurethane foam dressing includes a polyurethane film, a hydrophilic polyurethane foam layer compounded on the polyurethane film, a release paper provided on the hydrophilic polyurethane foam layer, and a soft silicone composite layer located below the release paper. The polyurethane film consists of a release film and a PU resin layer or TPU resin layer coated on the release film. Products prepared according to the disclosure not only can serve to absorb wound exudate of pressure sore, but also provides single-side water proofing; and it is sticky and can be stably fixed on the wound without easy displacement, thus ensuring continuous and stable liquid absorption.Type: ApplicationFiled: March 7, 2023Publication date: August 31, 2023Inventors: Liting CAO, Jianguo LU, Chao LIANG, Weijie WEI
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Publication number: 20230100446Abstract: The present disclosure provides an anti-infective and anti-adhesive wound dressing based on nonspecific adhesion to bacteria, which includes a micron-sized porous membrane with polyolefin contained in its surface and does not contain any bactericide. According to the disclosure, through targeted selection of a material and surface structure of the porous membrane, nonspecific adhesion to the bacteria on the wound surface can be formed by good adaptability of its own surface energy and the structure of the porous membrane to surface energy of the bacteria, preventing the bacteria from penetrating into wound tissues and thus realizing the anti-infection for the bacteria and the anti-adhesion to the wound. Furthermore, no bactericide is required to be added, which not only reduces infection of the wound, but also weakens factors which are not conducive to wound healing, such as aggravation of inflammation caused by bacterial toxin released after bacterial rupture in traditional sterilization mechanisms.Type: ApplicationFiled: September 27, 2022Publication date: March 30, 2023Inventors: Jianguo LU, Zhentan LU, Huan ZHANG
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Publication number: 20220401615Abstract: The present invention relates to a wound covering with prominent biocompatible and accelerated wound-healing and its preparation method thereof. The wound covering comprises a film prepared from collagen and Dopa-containing protein—mussel adhesive protein, which is immobilized on collagen by chemical cross-linking, thus enhances the stability of protein structure and maintains the activity of collagen and mussel adhesive protein. The wound covering has excellent mechanical strength and can be trimmed into any shape; it accelerates tissue epithelisation and promotes wound healing with good biocompatibility, non-adhesive to the wound and no further wound damages.Type: ApplicationFiled: August 25, 2022Publication date: December 22, 2022Applicant: Zhende Medical Co., Ltd.Inventors: Rui ZHANG, Jianguo LU, Luping ZHAO, Yu GONG
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Patent number: 11529262Abstract: A micro-negative pressure foam dressing and a manufacturing method thereof is disclosed, the dressing comprises a exothermic agent layer, an isolation component covering on the exothermic agent layer, an elastic memory piece disposed under the exothermic agent layer, a liquid absorbing negative pressure pad disposed under the elastic memory piece, a contact layer disposed under the liquid absorbing negative pressure pad, a sealing film disposed between the liquid absorbing negative pressure pad and the contact layer, and a bottom release film disposed under the contact layer; and in this invention, heat generated by a exothermic agent layer causes an elastic memory piece to expand downward to compress a foam layer, and after the heat dissipates completely, a micro-negative pressure is generated since a sealed environment is formed by a sealing film, a contact layer and a wound surface without a need for the VSD negative pressure technology.Type: GrantFiled: March 29, 2021Date of Patent: December 20, 2022Assignee: Zhende Medical Co., Ltd.Inventors: Feng Xia, Jianguo Lu
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Publication number: 20220339325Abstract: A corrosion-resistant and leak-proof stoma paste with self-regulation of strength is provided in this disclosure, with a formula comprising 4-40 parts of liquid rubber with a molecular weight ranging from 2000 to 5000, 8-18 parts of mineral oil, 14-34 parts of iota-carrageenan, 10-20 parts of plant polysaccharide and 15-20 parts of sericite, by weight. A product of the present disclosure can self-regulate hardness of the paste according to amount of stoma excreta through cooperation of the iota-carrageenan and the sericite to improve corrosion resistance of the paste; and synergistic effect provided by the iota-carrageenan and the sericite powder can improve strength and corrosion resistance of the paste.Type: ApplicationFiled: May 23, 2022Publication date: October 27, 2022Applicant: Zhende Medical Co., Ltd.Inventors: Lanqi FENG, Jianguo LU
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Publication number: 20220054428Abstract: The disclosure relates to a medical moisturizing eye patch with excellent biocompatibility and lasting moisture retention and a preparation method thereof, in which firstly, the standing cultured bacterial cellulose film is purified and bleached; then, the bleached bacterial cellulose wet film is composited with a moisturizing agent; then, a mechanical pressing is made to be with a proper liquid content; and finally, a cutting is made to obtain the eye patch with a proper size, which has excellent biocompatibility, high water holding capacity, high purity, high wet strength and excellent flexibility, excellent water absorption and water locking effect, improved skin moisture content, good air permeability, antibacterial function and no side-effect. The preparation method in the disclosure is simple and easy to realize; and the eye patch can be directly applied after peeling away the backing layer in use.Type: ApplicationFiled: November 8, 2021Publication date: February 24, 2022Applicant: Zhende Medical Co., Ltd.Inventors: Jiao WANG, Jianguo LU
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Publication number: 20210214475Abstract: A preparation method of PVA fiber comprises the following steps: preparing a spinning dope; PVAc is used as a raw material, and dissolved with addition of methanol before filtration, and then the spinning dope is obtained; spinning; the spinning dope is injected into a spinneret, and the ejected fibers are brought into a direct current electrolytic cell, and undergo a series of reactions of alcoholysis, electrolytic catalytic alcoholysis, and the levering of the alcohol; and the solution formulation in the electrolytic coagulation bath comprises alkali, alcohol and water; acid bath; through stretching, drying, washing with water, crimping with hot water and packaging, a finished polyvinyl alcohol fiber product is formed. The mirabilite is not needed in the coagulation bath, and PVA is obtained by the alcoholysis of PVAc in an electrolytic cell, and the produced PVA fibers present high purity and few impurities.Type: ApplicationFiled: March 29, 2021Publication date: July 15, 2021Applicant: Zhende Medical Co., Ltd.Inventor: Jianguo Lu
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Publication number: 20210212863Abstract: The invention discloses a micro-negative pressure foam dressing and a manufacturing method thereof, the dressing comprises a exothermic agent layer, an isolation component covering on the exothermic agent layer, an elastic memory piece disposed under the exothermic agent layer, a liquid absorbing negative pressure pad disposed under the elastic memory piece, a contact layer disposed under the liquid absorbing negative pressure pad, a sealing film disposed between the liquid absorbing negative pressure pad and the contact layer, and a bottom release film disposed under the contact layer; and in this invention, heat generated by a exothermic agent layer causes an elastic memory piece to expand downward to compress a foam layer, and after the heat dissipates completely, a micro-negative pressure is generated since a sealed environment is formed by a sealing film, a contact layer and a wound surface without a need for the VSD negative pressure technology, which is simple to operate, simple in structure, low in coType: ApplicationFiled: March 29, 2021Publication date: July 15, 2021Applicant: Zhende Medical Co., Ltd.Inventors: Feng XIA, Jianguo Lu
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Patent number: 10794421Abstract: An apparatus for preloading a bearing assembly on a shaft includes a first annular threaded member positioned about the shaft and a second annular threaded member positioned about the shaft. The first and second threaded members have intermeshing threads such that rotation of the second threaded member causes axial translation of the first threaded member to apply a first axial force to the bearing assembly to preload the bearing assembly. An actuator is operable to rotate the second threaded member relative to the first threaded member to apply the first axial force to the bearing assembly.Type: GrantFiled: March 1, 2016Date of Patent: October 6, 2020Assignee: The Timken CompanyInventors: Min Fang, Jianguo Lu, Xianghua Zhou
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Publication number: 20190072129Abstract: An apparatus (10) for preloading a bearing assembly (14) on a shaft (12) includes a first annular threaded member (56) positioned about the shaft (12) and a second annular threaded member (68) positioned about the shaft (12). The first and second threaded members (56,68) have intermeshing threads such that rotation of the second threaded member (68) causes axial translation of the first threaded member (56) to apply a first axial force to the bearing assembly (14) to preload the bearing assembly (14). An actuator is operable to rotate the second threaded member (68) relative to the first threaded member (56) to apply the first axial force to the bearing assembly (14).Type: ApplicationFiled: March 1, 2016Publication date: March 7, 2019Inventors: Min FANG, Jianguo LU, Xianghua ZHOU