Patents by Inventor Jian-Guo Ren

Jian-Guo Ren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10854875
    Abstract: The present disclosure relates to a method for making an electrode material of lithium-ion batteries. In the method, a lithium source solution and a plurality of titanium source particles are provided. The lithium source solution and the titanium source particles are mixed, wherein a molar ratio of lithium element to titanium element is in a range from about 4:5 to about 9:10, thereby forming a sol. A carbon source compound is dispersed into the sol to form a sol mixture. The sol mixture is spray dried to form a plurality of precursor particles. The precursor particles are heated to form a lithium titanate composite electrode material.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: December 1, 2020
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Jian Gao, Xiang-Ming He, Jian-Jun Li, Wei-Hua Pu, Jian-guo Ren, Li Wang
  • Patent number: 9931313
    Abstract: The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing proliferative disorders, such as cancel-, that result in dysregulation of malic enzyme 2. In particular, the methods and compositions include monotherapy with malate, or a derivative thereof, as well as combination therapy, such as malate, or a derivative thereof, combined with another therapeutic agent, such as a malic enzyme 2 inhibitor, an antineoplastic agent, a glycolysis inhibitor, an antiangiogenic agent, an immunomodulatory agent, an antibody, or a cytokine.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: April 3, 2018
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Vikas P. Sukhatme, Jian-Guo Ren
  • Patent number: 9923200
    Abstract: A method for making a sulfur-graphene composite material is provided. In the method, an elemental sulfur solution and a graphene dispersion are provided. The elemental sulfur solution includes a first solvent and an elemental sulfur dissolved in the first solvent. The graphene dispersion includes a second solvent and graphene sheets dispersed in the second solvent. The elemental sulfur solution is added to the graphene dispersion, a number of elemental sulfur particles are precipitated and attracted to a surface of the graphene sheets to form the sulfur-graphene composite material. The sulfur-graphene composite material is separated from the mixture.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: March 20, 2018
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Li Wang, Xiang-Ming He, Jian-Jun Li, Jian-Wei Guo, Wen-Ting Sun, Jian-Guo Ren
  • Publication number: 20170054149
    Abstract: A method for making a sulfur-graphene composite material is provided. In the method, an elemental sulfur solution and a graphene dispersion are provided. The elemental sulfur solution includes a first solvent and an elemental sulfur dissolved in the first solvent. The graphene dispersion includes a second solvent and graphene sheets dispersed in the second solvent. The elemental sulfur solution is added to the graphene dispersion, a number of elemental sulfur particles are precipitated and attracted to a surface of the graphene sheets to form the sulfur-graphene composite material. The sulfur-graphene composite material is separated from the mixture.
    Type: Application
    Filed: November 2, 2016
    Publication date: February 23, 2017
    Inventors: LI WANG, XIANG-MING HE, JIAN-JUN LI, JIAN-WEI GUO, WEN-TING SUN, JIAN-GUO REN
  • Patent number: 9539323
    Abstract: The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing cancer and other related diseases that result in dysregulation of malic enzyme 2. In particular, the methods and compositions include combination therapy, such as with a combination of two or more ME2 inhibitors or a combination of an ME2 inhibitor and an anticancer agent.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 10, 2017
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Vikas P. Sukhatme, Jian-Guo Ren
  • Patent number: 9425458
    Abstract: The present disclosure relates to a method for making an electrode material of lithium-ion batteries. In the method, a lithium source solution and a plurality of titanium source particles are provided. The lithium source solution and the titanium source particles are mixed, wherein a molar ratio of lithium element to titanium element is in a range from about 4:5 to about 9:10, thereby forming a sol. A carbon source compound is dispersed into the sol to form a sol mixture. The sol mixture is spray dried to form a plurality of precursor particles. The precursor particles are heated to form a lithium titanate composite electrode material.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: August 23, 2016
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Jian Gao, Xiang-Ming He, Jian-Jun Li, Wei-Hua Pu, Jian-Guo Ren, Li Wang
  • Publication number: 20160233483
    Abstract: The present disclosure relates to a method for making an electrode material of lithium-ion batteries. In the method, a lithium source solution and a plurality of titanium source particles are provided. The lithium source solution and the titanium source particles are mixed, wherein a molar ratio of lithium element to titanium element is in a range from about 4:5 to about 9:10, thereby forming a sol. A carbon source compound is dispersed into the sol to form a sol mixture. The sol mixture is spray dried to form a plurality of precursor particles. The precursor particles are heated to form a lithium titanate composite electrode material.
    Type: Application
    Filed: April 14, 2016
    Publication date: August 11, 2016
    Applicants: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: JIAN GAO, XIANG-MING HE, JIAN-JUN LI, WEI-HUA PU, JIAN-GUO REN, LI WANG
  • Patent number: 9334340
    Abstract: This disclosure is related to a method for making a phosphorated polymer for electrochemical reversible lithium storage. A mixture including organic polymer and phosphorus is first heated and then cooled down to room temperature. The mixture is immersed in an alkaline solution after cooling own to room temperature. The pH of the mixture is adjusted to be neutral after immersing in the alkaline solution. The alkaline solution is removed.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: May 10, 2016
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Li Wang, Xiang-Ming He, Jian-Guo Ren, Wei-Hua Pu, Jian-Jun Li, Jian Gao
  • Patent number: 9219280
    Abstract: The invention relates to a current collector. The current collector include a metal foil and a graphene film covered on at least one surface of the metal foil. The invention also relates to an electrode of an electrochemical battery and the electrochemical battery using the current collector.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: December 22, 2015
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Xiang-Ming He, Li Wang, Jian-Jun Li, Jian-Wei Guo, Jian-Guo Ren
  • Patent number: 9123942
    Abstract: A method for making a separator of a lithium ion battery is provided. In the method, a modifier, and a porous membrane are provided. The modifier is a mixture of a phosphorus source having a phosphate radical, a trivalent aluminum source, and a metallic oxide provided in a liquid phase solvent. The modifier is coated on a surface of the porous membrane to form a coating layer. The coated porous membrane is dried to form a modifier layer disposed on the surface of the porous membrane.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: September 1, 2015
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Xiang-Ming He, Wei-Hua Pu, Li-Chun Zhang, Jian-Guo Ren, Jian-Jun Li, Jian Gao
  • Patent number: 9017639
    Abstract: In the method for making graphene, an electrolyte solution is formed by dissolving an electrolyte lithium salt in an organic solvent. Lithium ions are separated out from the electrolyte lithium salt in the electrolyte solution. Metal lithium and graphite are disposed in the electrolyte solution, and the metal lithium and the graphite are in contact with each other. In the electrolyte solution, lithium ions and organic solvent molecules jointly insert between adjacent layers of the graphite to form a graphite intercalation compound. The graphene is peeled off from the graphite intercalation compound.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: April 28, 2015
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Xiang-Ming He, Li Wang, Jian-Jun Li, Jian-Wei Guo, Wen-Ting Sun, Jian-Guo Ren
  • Publication number: 20150056215
    Abstract: The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing proliferative disorders, such as cancel-, that result in dysregulation of malic enzyme 2. In particular, the methods and compositions include monotherapy with malate, or a derivative thereof, as well as combination therapy, such as malate, or a derivative thereof, combined with another therapeutic agent, such as a malic enzyme 2 inhibitor, an antineoplastic agent, a glycolysis inhibitor, an antiangiogenic agent, an immunomodulatory agent, an antibody, or a cytokine.
    Type: Application
    Filed: April 4, 2013
    Publication date: February 26, 2015
    Applicant: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Vikas P. Sukhatme, Jian-Guo Ren
  • Publication number: 20150051354
    Abstract: This disclosure is related to a method for making a phosphorated polymer for electrochemical reversible lithium storage. A mixture including organic polymer and phosphorus is first heated and then cooled down to room temperature. The mixture is immersed in an alkaline solution after cooling own to room temperature. The pH of the mixture is adjusted to be neutral after immersing in the alkaline solution. The alkaline solution is removed.
    Type: Application
    Filed: October 28, 2014
    Publication date: February 19, 2015
    Inventors: LI WANG, XIANG-MING HE, JIAN-GUO REN, WEI-HUA PU, JIAN-JUN LI, JIAN GAO
  • Patent number: 8916676
    Abstract: A method for making a phosphorated polymer is also provided. An organic polymer and phosphorus are mixed to obtain a mixture. A weight ratio of the organic polymer to the phosphorus ranges from about 1:10 to about 4:1. The mixture is dried in an inert atmosphere or vacuum. The mixture is heated in an inert atmosphere or vacuum so that the phosphorus sublimes and reacts with the organic polymer to form a preform. The preform is cooled down to room temperature and immersed in an alkaline solution. The pH of the preform is adjusted to be neutral. The preform is dried.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: December 23, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Li Wang, Xiang-Ming He, Jian-Guo Ren, Wei-Hua Pu, Jian-Jun Li, Jian Gao
  • Patent number: 8852800
    Abstract: A phosphorated composite capable of electrochemical reversible lithium storage includes a conductive matrix and red phosphorus. The conductive matrix includes a material being selected from the group consisting of conductive polymer and conductive carbonaceous material. A weight percentage of the conductive matrix in the phosphorated composite ranges from about 10% to about 85%. A weight percentage of the red phosphorus in the phosphorated composite ranges from about 15% to about 90%. An anode using the phosphorated composite is also provided.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: October 7, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Li Wang, Xiang-Ming He, Jian-Guo Ren, Wei-Hua Pu, Jian-Jun Li, Jian Gao
  • Patent number: 8821969
    Abstract: A method for making a modified current collector of a lithium ion battery is provided. In the method, the modifier and a metal plate are provided. The modifier is a mixture of a phosphorus source having a phosphate radical, a trivalent aluminum source, and a metallic oxide provided in a liquid phase solvent. The modifier is coated on a surface of the metal plate to form a coating layer. The coated metal plate is heat treated to transform the coating layer into a protective film formed on the surface of the metal plate.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: September 2, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Xiang-Ming He, Jian-Jun Li, Li-Chun Zhang, Wei-Hua Pu, Jian Gao, Jian-Guo Ren
  • Patent number: 8784693
    Abstract: A method for making a phosphorated composite is provided. First, a mixture is obtained by mixing a source material with red phosphorus. The weight ratio of the source material to the red phosphorus ranges from about 1:10 to about 5:1. Second, the mixture is dried in an inert atmosphere or vacuum. Third, the mixture is heated in a reacting room filled with an inert atmosphere so that the red phosphorus sublimes. Finally, the reacting room is cooled down.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: July 22, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Li Wang, Xiang-Ming He, Jian-Guo Ren, Wei-Hua Pu, Jian-Jun Li, Jian Gao
  • Patent number: 8765213
    Abstract: The present disclosure relates to a method for making an electrode material of lithium-ion batteries. In the method, a carbon source compound is dissolved into a solvent to form a liquid phase solution. A number of titanium dioxide particles are provided and are dispersed into the liquid phase solution. The carbon source compound is pyrolyzed, thereby forming a number of carbon coating titanium dioxide particles. A lithium source solution is provided. The lithium source solution and the carbon coating titanium dioxide particles are mixed, according to a molar ratio in a range from about 4:5 to about 9:10, of lithium element to titanium element, thereby forming a sol. The sol is spray dried to form a number of precursor particles. The precursor particles are heated to form a lithium titanate composite electrode material.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: July 1, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Li Wang, Xiang-Ming He, Jian-Guo Ren, Jian Gao, Jian-Jun Li, Wei-Hua Pu
  • Patent number: 8609183
    Abstract: A method for making sulfur-graphene composite material is disclosed. In the method, a dispersed solution including a solvent and a plurality of graphene sheets dispersed in the solvent is provided. A sulfur-source chemical compound is dissolved into the dispersed solution to form a mixture. A reactant, according to the sulfur-source chemical compound, is introduced to the mixture. Elemental sulfur is produced on a surface of the plurality of graphene sheets due to a redox reaction between the sulfur-source chemical compound and the reactant, to achieve the sulfur-graphene composite material. The sulfur-graphene composite material is separated from the solvent.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: December 17, 2013
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Li Wang, Xiang-Ming He, Jian-Jun Li, Jian-Wei Guo, Wen-Ting Sun, Jian-Guo Ren
  • Publication number: 20130209488
    Abstract: The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing cancer and other related diseases that result in dysregulation of malic enzyme 2. In particular, the methods and compositions include combination therapy, such as with a combination of two or more ME2 inhibitors or a combination of an ME2 inhibitor and an anticancer agent.
    Type: Application
    Filed: August 5, 2011
    Publication date: August 15, 2013
    Applicant: BETH ISRAEL DEACONESS MEDICAL CENTER, INC
    Inventors: Vikas P. Sukhatme, Jian-Guo Ren