Abstract: The present disclosure provides a high-efficiency filament helical winding device, which includes a frame body and a plurality of multi-filar guides. The frame body is provided with a through-hole, the plurality of multi-filar guides distributed in a circumference along a center of the through-hole are rotationally connected to the frame body and filament is extended out from each multi-filar guide in the plurality of multi-filar guides, and the frame body is provided with a first driving mechanism that drives each multi-filar guide to rotate.

Abstract: The present disclosure provides a high-efficiency filament helical winding device, which includes a frame body and a plurality of multi-filar guides. The frame body is provided with a through-hole, the plurality of multi-filar guides distributed in a circumference along a center of the through-hole are rotationally connected to the frame body and filament is extended out from each multi-filar guide in the plurality of multi-filar guides, and the frame body is provided with a first driving mechanism that drives each multi-filar guide to rotate.

Abstract: The present disclosure provides a high-efficiency filament helical winding device, which includes a frame body and a plurality of multi-filar guides. The frame body is provided with a through-hole, the plurality of multi-filar guides distributed in a circumference along a center of the through-hole are rotationally connected to the frame body and filament is extended out from each multi-filar guide in the plurality of multi-filar guides, and the frame body is provided with a first driving mechanism that drives each multi-filar guide to rotate.

Abstract: The present disclosure provides a high-efficiency filament helical winding device, which includes a frame body and a plurality of multi-filar guides. The frame body is provided with a through-hole, the plurality of multi-filar guides distributed in a circumference along a center of the through-hole are rotationally connected to the frame body and filament is extended out from each multi-filar guide in the plurality of multi-filar guides, and the frame body is provided with a first driving mechanism that drives each multi-filar guide to rotate.

Abstract: The present disclosure discloses a lighting device and a ceiling light, the lighting device includes: a chassis, at least one lighting module, a drive power supply, and a first mounting component; the lighting module and the drive power supply are arranged on the chassis; the first mounting component is configured to mount the lighting module and the drive power supply on the chassis in a covering mode, the first mounting component includes a main body unit, at least one first accommodating part, and at least one second accommodating part, the first accommodating part and the second accommodating part are both arranged on the main body unit; and one end of the lighting module is electrically connected in the first accommodating part, one end of the drive power supply is connected in the second accommodating part, and the drive power supply supplies power to the lighting module.

Abstract: Crystalline niraparib freebase is provided. Also provided are pharmaceutical compositions comprising crystalline niraparib freebase, and methods and uses pertaining to the same.

Abstract: Novel salts of niraparib are provided. Also provided are pharmaceutical compositions comprising those salts, as well as methods and uses pertaining to the same.

Abstract: A landscape advertising light, box type miniaturized substation, belonging to the field of substations. The landscape advertising light box type miniaturized substation includes a box body; the box body is internally provided with a ring main unit, a transformer and an integrated low-voltage cabinet; the integrated low-voltage cabinet includes an incoming switch, a capacitor switch, a capacitor and an outgoing switch which are electrically connected in sequence; an output end of the ring main unit is electrically connected with an input end of the transformer, and an output end of the transformer is electrically connected with an input end of the incoming switch; a display screen is disposed outside the box body.

Abstract: A landscape advertising light box type miniaturized substation, belonging to the field of substations. The landscape advertising light box type miniaturized substation includes a box body; the box body is internally provided with a ring main unit, a transformer and an integrated low-voltage cabinet; the integrated low-voltage cabinet includes an incoming switch, a capacitor switch, a capacitor and an outgoing switch which are electrically connected in sequence; an output end of the ring main unit is electrically connected with an input end of the transformer, and an output end of the transformer is electrically connected with an input end of the incoming switch; a display screen is disposed outside the box body.

Abstract: A water hammer-proof air valve that has a valve body and a bonnet, that are fixedly connected, a valve opening is provided on the valve body, and a high-speed intake and exhaust device is provided in an inner cavity of the valve body. A bonnet opening is provided on the bonnet, an output end of the high-speed intake and exhaust device penetrates the bonnet opening and is communicated with a high-speed exhaust throttling device for limiting an exhaust amount of gas of the high-speed intake and exhaust device, an output end of the high-speed exhaust throttling device is communicated with an outside air, and a trace exhaust device for discharging the gas separated out from the pipeline to the outside through the high-speed exhaust throttling device after the high-speed intake and exhaust device closes the valve is further provided in the high-speed intake and exhaust device.

Abstract: The present invention relates to processes for the preparation of N-protected (2S,5R)-6-hydroxy-7-oxo-N-piperidin-4-yl-1,6-diazabicyclo[3.2.1]octane-2-carboxamide intermediates. Such compounds have application in the preparation of beta-lactamase inhibitors such as 7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamides and esters, in particular, the beta lactamase inhibitor, (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. The present invention also encompasses intermediates useful in the disclosed processes and methods for their preparation.

Abstract: The present invention is directed to processes for preparing Substituted Tetracyclic Heterocycle Compounds of formula (I): (I) which may be useful as HCV NS5A inhibitors. The present invention is also directed to compounds that may be useful as synthetic intermediates and catalysts in the processes of the invention.

Abstract: The present invention relates to processes for the preparation of N-protected (2S,5R)-6-hydroxy-7-oxo-N-piperidin-4-yl-1,6-diazabicyclo[3.2.1]octane-2-carboxamide intermediates. Such compounds have application in the preparation of beta-lactamase inhibitors such as 7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamides and esters, in particular, the beta lactamase inhibitor, (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. The present invention also encompasses intermediates useful in the disclosed processes and methods for their preparation.

Abstract: The invention discloses a tilting disc check valve, which includes a left valve body (1), a right valve body (2), a large valve plate (3), a small valve plate (4) and a diaphragm control group (5), wherein the left valve body (1) and the right valve body (2) are butted into a whole through oblique openings; the oblique openings are inclined in a manner that upper parts are inclined towards the right valve body (2); the diaphragm control group (5) is arranged on the left valve body (1); the large valve plate (3) is arranged along the oblique openings; the large valve plate (3) is positioned in a valve cavity formed by the left valve body (1) and the right valve body (2); the large valve plate (3) is suspended on shaft holes of the left valve body (3) through valve shafts (6); the small valve plate (4) is connected with the diaphragm control group (5); and the small valve plate (4) is mounted at a slow closing valve port of the large valve plate (3) through a small valve plate pin shaft (7).

Abstract: The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.

Abstract: The present invention is directed to processes for preparing Substituted Tetracyclic Heterocycle Compounds of formula (I): (I) which may be useful as HCV NS5A inhibitors. The present invention is also directed to compounds that may be useful as synthetic intermediates and catalysts in the processes of the invention.

Abstract: A water hammer-proof air valve that has a valve body and a bonnet, that are fixedly connected, a valve opening is provided on the valve body, and a high-speed intake and exhaust device is provided in an inner cavity of the valve body. A bonnet opening is provided on the bonnet, an output end of the high-speed intake and exhaust device penetrates the bonnet opening and is communicated with a high-speed exhaust throttling device for limiting an exhaust amount of gas of the high-speed intake and exhaust device, an output end of the high-speed exhaust throttling device is communicated with an outside air, and a trace exhaust device for discharging the gas separated out from the pipeline to the outside through the high-speed exhaust throttling device after the high-speed intake and exhaust device closes the valve is further provided in the high-speed intake and exhaust device.

Abstract: The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.

Abstract: The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.

Abstract: The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine, utilizing a highly effective spiroacid synthesis.