Patents by Inventor Jiangyong Chen

Jiangyong Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole inhibitors of MDM2 and the uses thereof
    Patent number: 7737174
    Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: June 15, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: Shaomeng Wang, Dongguang Qin, Jiangyong Chen, Shanghai Yu
  • Gossypol co-crystals and the use thereof
    Patent number: 7432300
    Abstract: This invention relates to compositions comprising co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The invention also relates to the use of co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: October 7, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Shaomeng Wang, Jiangyong Chen
  • NEW SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF
    Publication number: 20080125430
    Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
    Type: Application
    Filed: August 30, 2007
    Publication date: May 29, 2008
    Applicant: The Regents of the University of Michigan
    Inventors: Shaomeng Wang, Dongguang Qin, Jiangyong Chen, Shanghai Yu
  • Gossypol co-crystals and the use thereof
    Patent number: 7342046
    Abstract: This invention relates to compositions comprising co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The invention also relates to the use of co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: March 11, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Shaomeng Wang, Jiangyong Chen
  • Gossypol co-crytals and the use thereof
    Publication number: 20070293585
    Abstract: This invention relates to compositions comprising co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The invention also relates to the use of co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.
    Type: Application
    Filed: June 15, 2007
    Publication date: December 20, 2007
    Inventors: Shaomeng Wang, Jiangyong Chen
  • Gossypol co-crystals and the use thereof
    Publication number: 20050234135
    Abstract: This invention relates to compositions comprising co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The invention also relates to the use of co-crystals of (?)-gossypol with a C1-8 carboxylic acid or C1-8 sulfonic acid for inducing apoptosis in cells and for sensitizing cells to the induction of apoptotic cell death.
    Type: Application
    Filed: March 24, 2005
    Publication date: October 20, 2005
    Inventors: Shaomeng Wang, Jiangyong Chen