Patents by Inventor Jianhong GUO

Jianhong GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132641
    Abstract: The present invention relates to an ultra-high molecular weight polyethylene and a process for preparing the same, said ultra-high molecular weight polyethylene has a viscosity-average molecular weight of 150-1000×104 g/mol, a metal element content of 0-50 ppm, a bulk density of 0.30-0.55 g/cm3, a true density of 0.900-0.940 g/cm3, a melting point of 140-152° C., and a crystallinity of 40-75%, and said polyethylene satisfies at least one of condition (1) and condition (2): Condition (1): tensile elasticity modulus is greater than 250 MPa, preferably greater than 280 MPa, more preferably greater than 300 MPa, Condition (2): Young's modulus is greater than 300 MPa, preferably greater than 350 MPa. The ultra-high molecular weight polyethylene has high mechanical properties, high melting point, low metal element content and ash content, and the preparation process is simple, flexible and adjustable, and the ultra-high molecular weight ethylene copolymer has a high tensile elasticity module.
    Type: Application
    Filed: January 26, 2022
    Publication date: April 25, 2024
    Inventors: Chuanfeng LI, Wenrui WANG, Kun JING, Yuejun XING, Huimin XIA, Minghua CHEN, Zhonglin YOU, Shaohui CHEN, Jianhong ZHAI, Feng GUO, Liu YANG
  • Publication number: 20240117085
    Abstract: The present invention relates to an ethylene polymer and a process for preparing the same, wherein the ethylene polymer has an average particle size of 50-3000 ?m, a bulk density of 0.28-0.55 g/cm3, a true density of 0.930-0.980 g/cm3, a melt index at a load of 2.16 Kg at 190° C. of 0.01-2500 g/10 min, a crystallinity of 30-90%, a melting point of 105-147° C., a comonomer molar insertion rate of 0.01-5 mol %, a weight-average molecular weight of 2×104 g/mol-40×104 g/mol, and a molecular weight distribution of 1.8-10. In the preparation process, raw materials containing ethylene, hydrogen gas and a comonomer are subjected to a tank-type slurry polymerization with an alkane solvent having a boiling point of 5-55° C. or a mixed alkane solvent having a saturated vapor pressure of 20-150 KPa at 20° C. as the polymerization solvent in the presence of a polyethylene catalytic system, at the molar ratio of hydrogen gas to ethylene of 0.01-20:1, preferably 0.
    Type: Application
    Filed: January 26, 2022
    Publication date: April 11, 2024
    Inventors: Chuanfeng LI, Wenrui WANG, Kun JING, Yuejun XING, Huimin XIA, Minghua CHEN, Zhonglin YOU, Shaohui CHEN, Jianhong ZHAI, Feng GUO, Liu YANG, Li MEI
  • Publication number: 20240092948
    Abstract: The present invention relates to a process for continuously producing an ultra-high molecular weight polyethylene by the ethylene slurry polymerization, wherein raw materials containing ethylene and optionally at least one comonomer are subjected to a continuous slurry polymerization in a hydrogen free atmosphere in the ethylene slurry polymerization condition by using 2-6 ethylene slurry polymerization reaction tanks connected in series, and the deviations of the polymerization temperatures, the polymerization pressures, and the gas phase compositions between the tanks each other are controlled to certain ranges. The ultra-high molecular weight polyethylene having the viscosity-average molecular weight of 150-800×104 g/mol can be continuously produced. This process has flexible polymerization manner, large room for adjusting and controlling, and stable polymer performance.
    Type: Application
    Filed: January 26, 2022
    Publication date: March 21, 2024
    Inventors: Chuanfeng LI, Wenrui WANG, Kun JING, Minghua CHEN, Yuejun XING, Huimin XIA, Feng GUO, Zhonglin YOU, Shaohui CHEN, Jianhong ZHAI, Liu YANG, Songtao TU
  • Patent number: 11883482
    Abstract: The disclosure provides a recombinant nucleic acid of Seneca valley virus, a recombinant vaccine strain and preparation method and use thereof, and relates to the technical field of genetic engineering. The disclosure provides the recombinant nucleic acid of Seneca valley virus, recombinant Seneca valley virus comprising the recombinant nucleic acid, recombinant Seneca valley virus encoded by the recombinant nucleic acid, recombinant Seneca valley virus vaccine strain comprising the recombinant Seneca valley virus and preparation method and use thereof. According to the disclosure, a vaccine strain characterized by high antigen production capacity, remarkably reduced pathogenicity (even having no pathogenicity to pigs), strong antibody induction activity, high immune protection rate is prepared. The vaccine strain remarkably improves the biological safety and can be used for preventing and controlling Seneca valley virus in China and the neighboring countries.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: January 30, 2024
    Inventors: Haixue Zheng, Fan Yang, Zixiang Zhu, Weijun Cao, Hong Tian, Keshan Zhang, Ting Wei, Min Zheng, Wei Zhang, Wen Dang, Xusheng Ma, Dan Li, Yi Ru, Jijun He, Jianhong Guo, Xiangtao Liu
  • Patent number: 11883411
    Abstract: The present disclosure belongs to the technical field of African swine fever (ASF) treatment, in particular to use of a compound aprepitant in prevention or treatment of the ASF. In the present disclosure, it is found that the compound aprepitant can significantly inhibit replication of an African swine fever virus (ASFV); in addition, it is found that the aprepitant inhibits transcription and protein expression of D1133L, and reduces transcription and protein expression levels of p30 and p72, preventing virus invasion on host cells. Therefore, the compound aprepitant can be used to inhibit early and late infection of the ASFV. Accordingly, the compound aprepitant can be used to prevent or treat the ASF.
    Type: Grant
    Filed: August 25, 2022
    Date of Patent: January 30, 2024
    Assignee: LANZHOU VETERINARY RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Keshan Zhang, Haixue Zheng, Huimei Cui, Bo Yang, Hong Tian, Zixiang Zhu, Tao Feng, Fan Yang, Weijun Cao, Xusheng Ma, Yi Ru, Jianhong Guo, Xiangtao Liu
  • Publication number: 20230295641
    Abstract: The present disclosure belongs to the technical field of biology, and in particular relates to an attenuated strain of African swine fever virus (ASFV) with IPTG-induced deletion of a D1133L gene and use thereof. In the present disclosure, it is firstly found that the D1133L protein of ASFV can inhibit production of IFN-? and downstream cytokines ISG-15 and ISG-56, and can be used as an immunosuppressant with a relatively strong immunosuppressive effect. In addition, the attenuated strain of ASFV with IPTG-induced deletion of the D1133L gene is constructed. Specifically, a screening expression cassette is inserted into a position before the non-structural protein gene D1133L of the ASFV using an Escherichia coli lac operator-repressor system, to obtain a recombinant virus. In the presence of the IPTG, the recombinant virus has similar characteristics to a wild-type virus; and in the absence of the IPTG, the expression of the D1133L protein is inhibited.
    Type: Application
    Filed: November 21, 2022
    Publication date: September 21, 2023
    Applicant: LANZHOU VETERINARY RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Haixue ZHENG, Keshan ZHANG, Ting ZHANG, Tao FENG, Bo YANG, Xing YANG, Xijuan SHI, Hong TIAN, Yi RU, Fan YANG, Zixiang ZHU, Jianhong GUO, Jijun HE, Xiangtao LIU
  • Publication number: 20230270747
    Abstract: The present disclosure belongs to the technical field of African swine fever (ASF) treatment, in particular to use of a compound aprepitant in prevention or treatment of the ASF. In the present disclosure, it is found that the compound aprepitant can significantly inhibit replication of an African swine fever virus (ASFV); in addition, it is found that the aprepitant inhibits transcription and protein expression of D1133L, and reduces transcription and protein expression levels of p30 and p72, preventing virus invasion on host cells. Therefore, the compound aprepitant can be used to inhibit early and late infection of the ASFV. Accordingly, the compound aprepitant can be used to prevent or treat the ASF.
    Type: Application
    Filed: August 25, 2022
    Publication date: August 31, 2023
    Applicant: LANZHOU VETERINARY RESEARCH INSTITUTE, CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Keshan ZHANG, Haixue ZHENG, Huimei CUI, Bo YANG, Hong TIAN, Zixiang ZHU, Tao FENG, Fan YANG, Weijun CAO, Xusheng MA, Yi RU, Jianhong GUO, Xiangtao LIU
  • Patent number: 11328857
    Abstract: A high-voltage isolation withstand planar transformer and its high-voltage insulation method are provided. An insulating medium is provided between low-voltage windings and high-voltage windings. High-frequency current flows through the windings and generates a high-frequency alternating magnetic field to achieve isolated energy transmission. The low-voltage windings are connected to low-voltage side connection terminals, and the high-voltage windings are connected to high-voltage side connection terminals through a high-voltage winding leading-out foil. An annular hollow part of the low-voltage windings and the high-voltage windings is provided with a magnetic core. A stress grading method is provided to control the distribution of the electric field around the high-voltage winding leading-out foil. A voltage-balancing element group provides a voltage potential with a gradient change between the high-voltage winding leading-out foil and the low-voltage windings.
    Type: Grant
    Filed: September 23, 2021
    Date of Patent: May 10, 2022
    Assignee: INSTITUTE OF ELECTRICAL ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Guoen Cao, Yibo Wang, Yong Zhao, Jianhong Guo
  • Publication number: 20220077515
    Abstract: A battery pack (12) includes one or more electrical battery cells (18). A battery management system (20) includes at least one electronic processor (24) configured to monitor parameters of the battery pack. At least one fault detection sensor includes at least one of: at least one gas sensor (36) configured to measure a gas evolving from the plurality of electrical battery cells; and a shock sensor (30) configured to measure an impact on the battery pack. A housing (16) encloses the plurality of electrical battery cells, the battery management system, and the at least one fault detection sensor. The battery management system is configured to perform a remediation action responsive to detection of a fault by the at least one fault detection sensor.
    Type: Application
    Filed: December 13, 2019
    Publication date: March 10, 2022
    Inventors: EVGENIY LEYVI, VIJAYA KUMAR AIYAWAR, MELINDA ZHAO, JOE DEMORE, JACK JIANHONG GUO, RAHUL SINGH, UDAY REDDY
  • Publication number: 20220031832
    Abstract: The disclosure provides a recombinant nucleic acid of Seneca valley virus, a recombinant vaccine strain and preparation method and use thereof, and relates to the technical field of genetic engineering. The disclosure provides the recombinant nucleic acid of Seneca valley virus, recombinant Seneca valley virus comprising the recombinant nucleic acid, recombinant Seneca valley virus encoded by the recombinant nucleic acid, recombinant Seneca valley virus vaccine strain comprising the recombinant Seneca valley virus and preparation method and use thereof. According to the disclosure, a vaccine strain characterized by high antigen production capacity, remarkably reduced pathogenicity (even having no pathogenicity to pigs), strong antibody induction activity, high immune protection rate is prepared. The vaccine strain remarkably improves the biological safety and can be used for preventing and controlling Seneca valley virus in China and the neighboring countries.
    Type: Application
    Filed: May 24, 2021
    Publication date: February 3, 2022
    Applicant: Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences
    Inventors: Haixue Zheng, Fan Yang, Zixiang Zhu, Weijun Cao, Hong Tian, Keshan Zhang, Ting Wei, Min Zheng, Wei Zhang, Wen Dang, Xusheng Ma, Dan Li, Yi Ru, Jijun He, Jianhong Guo, Xiangtao Liu
  • Publication number: 20220028603
    Abstract: A high-voltage isolation withstand planar transformer and its high-voltage insulation method are provided. An insulating medium is provided between low-voltage windings and high-voltage windings. High-frequency current flows through the windings and generates a high-frequency alternating magnetic field to achieve isolated energy transmission. The low-voltage windings are connected to low-voltage side connection terminals, and the high-voltage windings are connected to high-voltage side connection terminals through a high-voltage winding leading-out foil. An annular hollow part of the low-voltage windings and the high-voltage windings is provided with a magnetic core. A stress grading method is provided to control the distribution of the electric field around the high-voltage winding leading-out foil. A voltage-balancing element group provides a voltage potential with a gradient change between the high-voltage winding leading-out foil and the low-voltage windings.
    Type: Application
    Filed: September 23, 2021
    Publication date: January 27, 2022
    Applicant: INSTITUTE OF ELECTRICAL ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Guoen CAO, Yibo WANG, Yong ZHAO, Jianhong GUO
  • Publication number: 20210151984
    Abstract: A large-scale photovoltaic direct current (DC) series boost grid-connected system with a power balancer, including N photovoltaic DC converters and N?1 power balancers, wherein N?2. The output ends of the photovoltaic DC converters are connected successively in series and then connected to the DC grid, and the input ends of the photovoltaic DC converters are respectively connected to the output ends of the photovoltaic power generation unit. Among the photovoltaic DC converters, which are arranged successively in series, a power balancer is disposed between the input ends of two photovoltaic DC converters adjacent to each other. The N?1 power balancers are arranged corresponding to the set N?1 photovoltaic DC converters respectively to balance the input power of the corresponding photovoltaic DC converter, thereby eliminating a difference between the output voltages of the photovoltaic DC converters.
    Type: Application
    Filed: October 29, 2019
    Publication date: May 20, 2021
    Applicant: INSTITUTE OF ELECTRICAL ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Xinke HUANG, Huan WANG, Junlong LU, Yibo WANG, Jianhong GUO, Hongyang YOU, Xinlei ZHANG
  • Patent number: 10998723
    Abstract: A large-scale photovoltaic direct current (DC) series boost grid-connected system with a power balancer, including N photovoltaic DC converters and N?1 power balancers, wherein N?2. The output ends of the photovoltaic DC converters are connected successively in series and then connected to the DC grid, and the input ends of the photovoltaic DC converters are respectively connected to the output ends of the photovoltaic power generation unit. Among the photovoltaic DC converters, which are arranged successively in series, a power balancer is disposed between the input ends of two photovoltaic DC converters adjacent to each other. The N?1 power balancers are arranged corresponding to the set N?1 photovoltaic DC converters respectively to balance the input power of the corresponding photovoltaic DC converter, thereby eliminating a difference between the output voltages of the photovoltaic DC converters.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: May 4, 2021
    Assignee: INSTITUTE OF ELECTRICAL ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Xinke Huang, Huan Wang, Junlong Lu, Yibo Wang, Jianhong Guo, Hongyang You, Xinlei Zhang
  • Patent number: 10894081
    Abstract: The present disclosure relates to a foot-and-mouth disease virus vaccine composition, especially a recombinant bivalent vaccine composition against type O and type A foot-and-mouth disease viruses. The present disclosure further relates to a method for preparing the foot-and-mouth disease virus vaccine composition, and a use of the foot-and-mouth disease virus vaccine composition in preparing medicines for preventing and/or controlling foot-and-mouth disease in animals.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: January 19, 2021
    Assignee: LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Haixue Zheng, Fan Yang, Zixiang Zhu, Weijun Cao, Hong Tian, Keshan Zhang, Dan Li, Ye Jin, Jianhong Guo, Jijun He, Xuepeng Cai, Xiangtao Liu
  • Publication number: 20200237897
    Abstract: The present disclosure relates to a foot-and-mouth disease virus vaccine composition, especially a recombinant bivalent vaccine composition against type O and type A foot-and-mouth disease viruses. The present disclosure further relates to a method for preparing the foot-and-mouth disease virus vaccine composition, and a use of the foot-and-mouth disease virus vaccine composition in preparing medicines for preventing and/or controlling foot-and-mouth disease in animals.
    Type: Application
    Filed: March 23, 2018
    Publication date: July 30, 2020
    Inventors: Haixue ZHENG, Fan YANG, Zixiang ZHU, Weijun CAO, Hong TIAN, Keshan ZHANG, Dan LI, Ye JIN, Jianhong GUO, Jijun HE, Xuepeng CAI, Xiangtao LIU