Patents by Inventor Jianhua Cao

Jianhua Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190211010
    Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
    Type: Application
    Filed: September 6, 2017
    Publication date: July 11, 2019
    Inventors: Xuxing CHEN, Meiyu GENG, Lei JIANG, Yi CHEN, Jianhua CAO, Qingyun JIANG, Qianqian SHEN, Jian DING, Yucai YAO, Zhao ZHAO, Yuanfang XIONG
  • Publication number: 20190111056
    Abstract: Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof.
    Type: Application
    Filed: March 21, 2017
    Publication date: April 18, 2019
    Inventors: Lei JIANG, Meiyu GENG, Qiangang ZHENG, Min HUANG, Huixin WAN, Shuai TANG, Xianlei FU, Xiaojing LAN, Jianhua CAO, Feifei LIU, Jian DING
  • Patent number: 10138212
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: November 27, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • Publication number: 20180282277
    Abstract: Disclosed are a method for preparing a series of carbazole derivatives and use thereof in organic light-emitting diodes. The structure of the material is as shown in Formula I. An organic electroluminescent device prepared by the material can have a significantly improved power efficiency and an external quantum efficiency for the device and an extended life for an orange light or red light device; moreover, the material has characteristics, for example, methods for the synthesis and purification of the material are simple and suitable for large-scale production, and is an ideal choice as a luminescent material for organic electroluminescent devices. The use of the organic electroluminescent diode material as a carrier transport material or as a luminescent material alone or as a host material in a light-emitting layer also falls within the scope of protection.
    Type: Application
    Filed: September 25, 2017
    Publication date: October 4, 2018
    Inventors: Jianhua CAO, Shibo WANG, Ruimao HUA
  • Publication number: 20180037554
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Application
    Filed: February 1, 2016
    Publication date: February 8, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • Publication number: 20170353647
    Abstract: A live image transferring method includes the steps of capturing live image information by one or more live image devices, wherein the live image information is captured in raw format and is continuously transferred to one or more platforms in a live manner; cloning the live image information at the platform, wherein when the live image information is cloned at the platform, the live image information is converted from the raw format into a web viewable format and an embed code is generated corresponding to the live image information at the same time; and enabling one or more users to use the embed code in order to broadcast the live image information over any website. The user is able to copy-and-paste the embed code at the personal website to live stream the live image information from the live image device.
    Type: Application
    Filed: June 13, 2017
    Publication date: December 7, 2017
    Inventor: Jianhua CAO
  • Publication number: 20170275291
    Abstract: The present invention provides an indazole compound as a FGFR kinase inhibitor, preparation and use thereof. Specifically, the present invention provides a compound represented by formula (I), wherein the definitions of each group are described in the specification. The compound of the present invention has good FGFR kinase-inhibiting activity, and can be used in preparing a series of medicines for treating FGFR kinase activity related diseases.
    Type: Application
    Filed: August 19, 2015
    Publication date: September 28, 2017
    Applicants: Shanghai Haihe Pharmaceutical Co., Ltd., Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Meiyu GENG, Lei LIU, Lei JIANG, Min HUANG, Chuantao ZHA, Jing AI, Lei WANG, Jianhua CAO, Jian DING
  • Patent number: 9774767
    Abstract: An Internet protocol (IP) camera includes a housing having a capturing window, a capturing unit received in the housing for capturing images as data sets through the capturing window, and a card window arrangement which includes a card slot unit for replaceably receiving a digital memory card to store the data sets therein and a concealing cover detachably coupled at the housing to conceal the card slot unit in a waterproof and dustproof manner without disassembling the housing.
    Type: Grant
    Filed: November 29, 2015
    Date of Patent: September 26, 2017
    Inventor: Jianhua Cao
  • Publication number: 20170240539
    Abstract: The present invention relates to cyclic sulfonamide derivatives of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 9, 2015
    Publication date: August 24, 2017
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Andrew W. Stamford, Zhi-Qiang Yang, Milana Maletic, Senlin Cai, Xiaobang Duan, Jianhua Cao
  • Patent number: 9712733
    Abstract: A live image transferring method includes the steps of capturing live image information by one or more live image devices, wherein the live image information is captured in raw format and is continuously transferred to one or more platforms in a live manner; cloning the live image information at the platform, wherein when the live image information is cloned at the platform, the live image information is converted from the raw format into a web viewable format and an embed code is generated corresponding to the live image information at the same time; and enabling one or more users to use the embed code in order to broadcast the live image information over any website. The user is able to copy-and-paste the embed code at the personal website to live stream the live image information from the live image device.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 18, 2017
    Inventor: Jianhua Cao
  • Publication number: 20170155970
    Abstract: A plug and play method of viewing live and recorded contents includes the steps of: requesting information of a capturing device by a remote control center; sending an accessing request from an Internet-enabled receiving device to the remote control center through Internet; verifying whether the information of the capturing device matches with the accessing request from the receiving device by the remote control center; and establishing a communication channel between the capturing device and the receiving device to enable contents captured by the capturing device to be transmitted to the receiving device in a live manner through Internet.
    Type: Application
    Filed: October 19, 2016
    Publication date: June 1, 2017
    Inventor: Jianhua Cao
  • Publication number: 20170155806
    Abstract: An Internet protocol (IP) camera includes a housing having a capturing window, a capturing unit received in the housing for capturing images as data sets through the capturing window, and a card window arrangement which includes a card slot unit for replaceably receiving a digital memory card to store the data sets therein and a concealing cover detachably coupled at the housing to conceal the card slot unit in a waterproof and dustproof manner without disassembling the housing.
    Type: Application
    Filed: November 29, 2015
    Publication date: June 1, 2017
    Inventor: Jianhua Cao
  • Patent number: 9510034
    Abstract: A plug and play method of viewing live and recorded contents includes the steps of: requesting information of a capturing device by a remote control center; sending an accessing request from an Internet-enabled receiving device to the remote control center through Internet; verifying whether the information of the capturing device matches with the accessing request from the receiving device by the remote control center; and establishing a communication channel between the capturing device and the receiving device to enable contents captured by the capturing device to be transmitted to the receiving device in a live manner through Internet.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: November 29, 2016
    Inventor: Jianhua Cao
  • Patent number: 9347153
    Abstract: A cheek plate device for a stuffer box crimper, comprising a bracket, adjusting mechanisms, cheek plates, a base, a pair of nip rollers and thrust devices. The adjusting mechanisms, which can slide relative to the bracket, are arranged on the bracket, the cheek plates are installed on the inner sides of the adjusting mechanisms, a pair of identical brackets, adjusting mechanisms and cheek plates are symmetrically installed on each side of the pair of nip rollers and affixed on the base. The adjusting mechanisms have adjusting blocks and elastic devices, the elastic devices are installed at the ends of the adjusting blocks and push against the thrust devices, the thrust devices push the adjusting blocks via the elastic devices, and the adjusting blocks push the two cheek plates moving towards the sides of the pair of nip rollers.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: May 24, 2016
    Assignee: NANTONG CELLULOSE FIBERS CO., LTD.
    Inventors: Baoru Yang, Jianhua Cao
  • Patent number: 9322118
    Abstract: A cheek plate device is provided for a stuffer box crimper, which has brackets, adjusting mechanisms, cheek plates, a base frame and a pair of nip rollers. The adjusting mechanisms are mounted on the brackets, which can slide relative to the bracket. The cheek plates are mounted on the inside of the adjusting mechanisms. Two identical brackets, adjusting mechanisms and cheek plates are mounted symmetrically at two sides of the pair of nip rollers and affixed on the base frame. The cheek plate device further comprises fluid thrust devices, which include fluid inlets and cylinders located on the brackets. One end of the adjusting mechanism is inserted into and coupled with the cylinder. The fluid of the thrust device flows into the cylinders through the inlets and pushes, via the adjusting mechanisms, the cheek plates toward the sides of the nip rollers. The thrust device can work hydraulically or pneumatically.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: April 26, 2016
    Assignee: NANTONG CELLULOSE FIBERS CO., LTD.
    Inventors: Baoru Yang, Jianhua Cao
  • Publication number: 20160088329
    Abstract: A plug and play method of viewing live and recorded contents includes the steps of: requesting information of a capturing device by a remote control center; sending an accessing request from an Internet-enabled receiving device to the remote control center through Internet; verifying whether the information of the capturing device matches with the accessing request from the receiving device by the remote control center; and establishing a communication channel between the capturing device and the receiving device to enable contents captured by the capturing device to be transmitted to the receiving device in a live manner through Internet.
    Type: Application
    Filed: March 26, 2015
    Publication date: March 24, 2016
    Inventor: Jianhua Cao
  • Patent number: 9124946
    Abstract: A plug and play method of viewing live and recorded contents includes the steps of: requesting information of a capturing device by a remote control center; sending an accessing request from an Internet-enabled receiving device to the remote control center through Internet; verifying whether the information of the capturing device matches with the accessing request from the receiving device by the remote control center; and establishing a communication channel between the capturing device and the receiving device to enable contents captured by the capturing device to be transmitted to the receiving device in a live manner through Internet.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: September 1, 2015
    Assignee: MICROSEVEN SYSTEMS, LLC.
    Inventor: Jianhua Cao
  • Patent number: 8827672
    Abstract: The present invention relates to an electrospinning device for fabricating a membrane, in particular, to an electrospinning device for fabricating membrane by using spinnerets aligned in machine direction (MD) and transverse direction (TD) in a high-voltage DC electric field, and to method for using the same. In addition to producing a single-layer nanofiber membrane from a polymer composite, the electrospinning device according to the present invention can also conveniently produce a multilayer composite nanofiber membrane from more than one polymer composites. The electrospinning device comprises a control section, an electrospinning section and an ancillary section. The electrospinning section comprises a MD spinnerets set and a TD spinnerets set that are alternately arranged and moves above a membrane collecting device in a to-and-fro scanning manner so as to improve the evenness and strength of the obtained membrane.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: September 9, 2014
    Assignee: SKPB Membrane-Tech (Beijing) Corporation
    Inventors: Dayong Wu, Haiyan Wang, Jianhua Cao
  • Publication number: 20140150226
    Abstract: A cheek plate device is provided for a stuffer box crimper, which has brackets, adjusting mechanisms, cheek plates, a base frame and a pair of nip rollers. The adjusting mechanisms are mounted on the brackets, which can slide relative to the bracket. The cheek plates are mounted on the inside of the adjusting mechanisms. Two identical brackets, adjusting mechanisms and cheek plates are mounted symmetrically at two sides of the pair of nip rollers and affixed on the base frame. The cheek plate device further comprises fluid thrust devices, which include fluid inlets and cylinders located on the brackets. One end of the adjusting mechanism is inserted into and coupled with the cylinder. The fluid of the thrust device flows into the cylinders through the inlets and pushes, via the adjusting mechanisms, the cheek plates toward the sides of the nip rollers. The thrust device can work hydraulically or pneumatically.
    Type: Application
    Filed: June 15, 2012
    Publication date: June 5, 2014
    Applicant: NANTONG CELLULOSE FIBERS CO., LTD.
    Inventors: Baoru Yang, Jianhua Cao
  • Patent number: 8716312
    Abstract: The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 6, 2014
    Assignee: Merck Sharp & Dohme Corporation
    Inventors: Pauline C. Ting, Robert Aslanian, Mary Ann Caplen, Jianhua Cao, Tin-Yau Chan, David Kim, Hyunjin Kim, Jae-Hun Kim, Rongze Kuang, Joe F. Lee, John Schwerdt, Heping Wu, Nicolas Zorn