Patents by Inventor Jianhua LE

Jianhua LE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid influenza seed viruses, compositions thereof, and use thereof in the diagnosis or therapy of influenza
    Patent number: 10435462
    Abstract: The invention provides antibody reagents for screening for seed viruses, in particular, antibodies that bind to one or more discontinuous epitopes in hemagglutinin (HA) polypeptide of human influenza virus (H1N1 strain). Additionally, the invention relates to compositions, kits, supports, and biologicals comprising the antibodies or fragments thereof. Also provided are nucleic acids encoding such antibodies or fragments, including, cells and/or hybridomas which generate such molecules. Additional embodiments relate to the immunogens useful in generating the antibodies, including nucleic acids encoding such immunogens, and compositions comprising such immunogens. Further embodiments relate to methods for screening for seed viruses, including human influenza type A virus seed viruses, using the antibodies or fragments thereof.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: October 8, 2019
    Assignee: VIRO DYNAMICS CORPORATION
    Inventors: Doris Bucher, Yu He, Jianhua Le, Manojkumar Ramanunninair
  • HYBRID INFLUENZA SEED VIRUSES, COMPOSITIONS THEREOF, AND USE THEREOF IN THE DIAGNOSIS OR THERAPY OF INFLUENZA
    Publication number: 20160289304
    Abstract: The invention provides antibody reagents for screening for seed viruses, in particular, antibodies that bind to one or more discontinuous epitopes in hemagglutinin (HA) polypeptide of human influenza virus (H1N1 strain). Additionally, the invention relates to compositions, kits, supports, and biologicals comprising the antibodies or fragments thereof. Also provided are nucleic acids encoding such antibodies or fragments, including, cells and/or hybridomas which generate such molecules. Additional embodiments relate to the immunogens useful in generating the antibodies, including nucleic acids encoding such immunogens, and compositions comprising such immunogens. Further embodiments relate to methods for screening for seed viruses, including human influenza type A virus seed viruses, using the antibodies or fragments thereof.
    Type: Application
    Filed: March 30, 2016
    Publication date: October 6, 2016
    Applicant: VIRO DYNAMICS CORPORATION
    Inventors: Doris BUCHER, Yu HE, Jianhua LE, Manojkumar RAMANUNNINAIR