Patents by Inventor Jianhua Mao

Jianhua Mao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230333097
    Abstract: The present disclosure provides a kit for detecting an anti-vinculin-immunoglobulin G (IgG) antibody, including the antigen protein vinculin, a solid phase carrier, a labeled antibody, an antigen diluent, a sample dilution buffer, an antibody diluent, a substrate color development reagent, a washing solution, a standard, a positive quality control, and negative quality control. In the present disclosure, the kit can detect the anti-Vinculin-IgG antibody in a sample to be tested by indirect reaction combined with magnetic particle-based chemiluminescence immunoassay. Autoantibodies against the target antigen vinculin are identified in the serum of a patient with autoimmune nephrotic syndrome for the first time, and a detection kit is provided for the autoantibodies. The present disclosure provides a basis for molecular mechanism research and clinical diagnosis and treatment of autoimmune nephrotic syndrome related to vinculin and vinculin-IgG autoantibodies at home and abroad.
    Type: Application
    Filed: July 1, 2022
    Publication date: October 19, 2023
    Applicant: ZHEJIANG UNIVERSITY
    Inventors: Qing YE, Jianhua MAO, Dandan TIAN
  • Publication number: 20230333115
    Abstract: The present disclosure provides a kit for detecting an anti-proteasome subunit alpha type 1-immunoglobulin G (IgG) antibody, including an antigen protein proteasome subunit alpha type 1, a solid phase carrier, a labeled antibody, an antigen diluent, a sample dilution buffer, an antibody diluent, a substrate color development reagent, a washing solution, a standard, a positive quality control, and a negative quality control. In the present disclosure, the kit is capable of detecting the anti-proteasome subunit alpha type 1-IgG antibody in serum to be tested by indirect reaction combined with magnetic particle-based chemiluminescence immunoassay. Autoantibodies against the target antigen protein proteasome subunit alpha type 1 are identified in the serum of a patient with autoimmune nephrotic syndrome for the first time.
    Type: Application
    Filed: July 1, 2022
    Publication date: October 19, 2023
    Applicant: ZHEJIANG UNIVERSITY
    Inventors: Qing YE, Jianhua MAO, Dandan TIAN
  • Publication number: 20230137023
    Abstract: Disclosed is a method for preparing compound S-1 (S-1) comprising resolving compound rac-2 (rac-2) with a compound of Formula 3 wherein R1, R4, m and n are as defined in the disclosure.
    Type: Application
    Filed: February 10, 2021
    Publication date: May 4, 2023
    Inventors: Richard M. CORBETT, Ravindra V. DATAR, Indrajeet M. JAMANE, Jianhua MAO, Shaileshkumar K. PATEL, Dongjie PENG
  • Publication number: 20230117284
    Abstract: Disclosed are methods for preparing compound S-1 (S-1) from (R)-2-bromobutanoic acid prepared by treating (R)-2-aminobutanoic acid with an alkali metal nitrite compound and hydrobromic acid.
    Type: Application
    Filed: February 10, 2021
    Publication date: April 20, 2023
    Inventors: Ravindra V. DATAR, Jianhua MAO
  • Publication number: 20230103936
    Abstract: Disclosed is a method for preparing compound Formula S-1, comprising resolving compound Formula rac-2 with a compound of Formula 3 wherein R1┬ĚR4, m and n are as defined in the disclosure.
    Type: Application
    Filed: February 10, 2021
    Publication date: April 6, 2023
    Inventors: Ravindra V. DATAR, Jianhua MAO, Shaileshkumar K. PATEL
  • Publication number: 20230096826
    Abstract: Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3-dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.
    Type: Application
    Filed: November 29, 2022
    Publication date: March 30, 2023
    Inventors: Liang CHEN, Yefeng FAN, Jianhua MAO, Zhijian XU
  • Patent number: 11569715
    Abstract: The integrated dual-motor controller includes a controller housing, a bus magnetic ring component, an all-in-one module, a control plate, an isolation plate and a drive plate. The bus magnetic ring component, the all-in-one module, the control plate, the isolation plate and the drive plate are all integrated in the controller housing. The integrated dual-motor controller is designed to achieve a high level of integration, and a modular design is used inside to facilitate mounting and reduce the size.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: January 31, 2023
    Assignee: Hefei Jee Power Systems, Co., Ltd.
    Inventors: Shuwang Wang, Feng Liu, Jianhua Mao, Yong Cheng, Chunzhe Sun, Jialun Fan, Hongyu Zhang
  • Publication number: 20230022378
    Abstract: Described herein are novel methods of synthesizing Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate.
    Type: Application
    Filed: November 11, 2020
    Publication date: January 26, 2023
    Inventors: Shuren Ji, Jie Luan, Jianhua Mao, Hao Wang, YiHui Xu
  • Publication number: 20230018429
    Abstract: Described herein are novel methods of synthesizing (3-chloro-2-pyridyl)hydrazine. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.
    Type: Application
    Filed: November 22, 2020
    Publication date: January 19, 2023
    Inventors: DEVARAJAN CHOCKALINGAM, VIPUL DUDHAT, RAJU MAHADEV KHARATKAR, JIANHUA MAO, PANKAJKUMAR VEKARIYA, DHARMESH BALVANTRAI BHATT
  • Publication number: 20230005812
    Abstract: Disclosed are an IGBT package heat dissipation structure and a motor controller applying the same. The IGBT package heat dissipation structure includes a heat dissipation substrate body, heat dissipation fins and electrodes respectively fixed on two sides of the heat dissipation substrate body. Each heat dissipation fin is provided with an inner cavity, a wafer, a first DBC layer and a second DBC layer are arranged in the inner cavity, an electrode is extended through the heat dissipation substrate body, and connected with the wafer through the first DBC layer and the second DBC layer.
    Type: Application
    Filed: March 31, 2022
    Publication date: January 5, 2023
    Applicant: HEFEI JEE POWER SYSTEMS CO., LTD.
    Inventors: Lei LIU, Jie GU, Jianhua MAO, Yong CHENG
  • Patent number: 11542241
    Abstract: Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3-dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: January 3, 2023
    Assignees: FMC Corporation, FMC Argo Singapore Pte. Ltd.
    Inventors: Liang Chen, Yefeng Fan, Jianhua Mao, Zhijian Xu
  • Publication number: 20220396560
    Abstract: Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives. Also described herein are novel reaction intermediates.
    Type: Application
    Filed: October 16, 2020
    Publication date: December 15, 2022
    Inventors: Yanchun CAO, Xin LIU, Jianhua MAO, Zhijian XU
  • Patent number: 11489398
    Abstract: The water channel structure for connecting a controller to a motor includes a controller main housing and a motor body that are connected and fastened to each other. A water-cooling plate is fastened in the controller main housing. A water inlet and a water outlet are respectively provided at two ends of the controller main housing. A heat dissipation water channel communicating the water inlet with the water outlet inside the controller main housing is formed in the water-cooling plate. A motor water channel is provided inside the motor body. A transition water joint is provided at the water outlet of the controller main housing. The transition water joint is directly connected to a water inlet of the motor water channel.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 1, 2022
    Assignee: HEFEI JEE POWER SYSTEMS CO., LTD.
    Inventors: Lei Liu, Jianhua Mao, Zhan Wang, Hongxin Wu, Yang Yang
  • Publication number: 20220289706
    Abstract: Disclosed a method for preparing compound of Formula (I) and (II) wherein R1, R2, R3, X and n are as defined in the disclosure.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 15, 2022
    Inventors: Jianhua MAO, Jingyi MA, Dongjie PENG, Chunyan HUO
  • Publication number: 20220267296
    Abstract: Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives. Also described herein are novel reaction intermediates.
    Type: Application
    Filed: October 16, 2020
    Publication date: August 25, 2022
    Inventors: Yanchun CAO, Liang CHEN, Jianhua MAO, Zhijian XU
  • Publication number: 20220259178
    Abstract: Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives. Also described herein are novel reaction intermediates.
    Type: Application
    Filed: October 16, 2020
    Publication date: August 18, 2022
    Inventors: Yanchun CAO, Xin LIU, Jianhua MAO, Zhijian XU
  • Publication number: 20220259177
    Abstract: Described herein are novel methods of synthesizing 5-Bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid from pyrazole or pyrazole derivatives. Also described herein are novel reaction intermediates.
    Type: Application
    Filed: October 16, 2020
    Publication date: August 18, 2022
    Inventors: Yanchun CAO, Xin LIU, Jianhua MAO, Zhijian XU
  • Publication number: 20220242837
    Abstract: Described herein are novel methods of synthesizing 2-amino-5-chloro-N,3-dimethylbenzamide. Compounds prepared by the methods disclosed herein are useful for preparation of certain anthranilamide compounds that are of interest as insecticides, such as, for example, the insecticides chlorantraniliprole and cyantraniliprole.
    Type: Application
    Filed: April 15, 2022
    Publication date: August 4, 2022
    Inventors: Liang CHEN, Yefeng FAN, Jianhua MAO, Zhijian XU
  • Publication number: 20210408873
    Abstract: The integrated dual-motor controller includes a controller housing, a bus magnetic ring component, an all-in-one module, a control plate, an isolation plate and a drive plate. The bus magnetic ring component, the all-in-one module, the control plate, the isolation plate and the drive plate are all integrated in the controller housing. The integrated dual-motor controller is designed to achieve a high level of integration, and a modular design is used inside to facilitate mounting and reduce the size.
    Type: Application
    Filed: December 30, 2019
    Publication date: December 30, 2021
    Inventors: Shuwang WANG, Feng LIU, Jianhua MAO, Yong CHENG, Chunzhe SUN, Jialun FAN, Hongyu ZHANG
  • Patent number: 11109518
    Abstract: A water-cooled motor controller includes a capacitor, a water-cooled plate, and a power module stacked in a controller housing. The power module is fixedly connected to the water-cooled plate. The water-cooled plate is provided with a cooling medium flow channel on one side facing the power module, and the other side of the water-cooling plate on which the cooling medium flow channel faces away from the power module side contacts the capacitor through an insulating and thermally conductive material for heat exchange. The water-cooled plate and the controller housing are fixedly connected to each other with a cooling medium passage provided therebetween. A cooling medium flows in from the controller housing, and then flows out of the controller housing after being heat exchanged by the water-cooled plate. The present invention utilizes upper and lower surfaces of the water-cooled plate to dissipate heat from the capacitor and the power module simultaneously.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: August 31, 2021
    Assignee: Hefei Jee Power Systems, Co., Ltd.
    Inventors: Lei Liu, Hongxin Wu, Rui Shang, Yang Yang, Yong Cheng, Jianhua Mao