Abstract: An electronic cigarette atomizer and an electronic cigarette are disclosed. The electronic cigarette atomizer comprises an air inlet (1), an air inlet passage (2), an atomization cavity (3), an air outlet passage (4), an air outlet (5), and a suction nozzle (6) that are communicated in sequence. The electronic cigarette atomizer further comprises a housing (8) and an adjustment mechanism (7) for adjusting the air input of the air inlet (1). The air inlet passage (2), the atomization cavity (3), and the air outlet passage (4) are all arranged in the housing (8), and a top of the housing (8) is provided with a top cover (9). The adjustment mechanism (7) comprises a movable member (10) located in the top cover (9) and movable axially along the top cover (9).

Abstract: Disclosed herein is a liquid crystal mixture applied in light modulating devices, comprising: component A comprised of one or more compounds selected from the group of compounds of formula (I), component B comprised of one or more compounds selected from the group of compounds of formula (II), and component C comprised of one or more chiral compounds. Also disclosed is a light modulating device containing the liquid crystal mixture, wherein the liquid crystal mixture has higher stability of electrical performance and the light modulating device has improved optical performance.

Abstract: The present disclosure relates to an image processing method. The method may include: obtaining image data; reconstructing an image based on the image data, the image including one or more first edges; obtaining a model, the model including one or more second edges corresponding to the one or more first edges; matching the model and the image; and adjusting the one or more second edges of the model based on the one or more first edges.

Abstract: An optoelectronic computing system includes a first semiconductor die having a photonic integrated circuit (PIC) and a second semiconductor die having an electronic integrated circuit (EIC). The PIC includes optical waveguides, in which input values are encoded on respective optical signals carried by the optical waveguides. The PIC includes an optical copying distribution network having optical splitters. The PIC includes an array of optoelectronic circuitry sections, each receiving an optical wave from one of the output ports of the optical copying distribution network, and each optoelectronic circuitry section includes: at least one photodetector detecting at least one optical wave from the optoelectronic operation. The EIC includes electrical input ports receiving respective electrical values.

Abstract: An electronic cigarette atomization core and atomizer is disclosed. The electronic cigarette atomization core includes an atomization member (3), an outer sleeve (24), a connection sleeve (22), and atomization cotton (14). A lower segment of the connection sleeve (22) is sleeved outside an upper segment of the outer sleeve (24). The outer sleeve (24) is sleeved outside the atomization cotton (14). The outer sleeve (24) is provided with a first e-liquid passage hole (2401) capable of communicating an inner cavity of an electronic cigarette e-liquid bin (12) with the atomization cotton (14). The connection sleeve (22) is axially movable or circumferentially rotatable relative to the outer sleeve (24) to close or open the first e-liquid passage hole (2401). A buffer sealing structure is arranged between the connection sleeve (22) and the outer sleeve (24).

Abstract: The present disclosure provides image processing systems and methods. An image processing method may include identifying a target region of an image, wherein the target region includes a tubular structure to be segmented; constructing a distance field of the target region based on a trained model, wherein the distance field includes elements each of which is associated with a distance between the element and a predicted centerline of the tubular structure; and segmenting the tubular structure to obtain a segmented tubular structure based on the distance field and an optimum path algorithm.

Abstract: The present disclosure relates to an image processing method. The method may include: obtaining image data; reconstructing an image based on the image data, the image including one or more first edges; obtaining a model, the model including one or more second edges corresponding to the one or more first edges; matching the model and the image; and adjusting the one or more second edges of the model based on the one or more first edges.

Abstract: The present disclosure relates to an image processing method. The method may include: obtaining image data; reconstructing an image based on the image data, the image including one or more first edges; obtaining a model, the model including one or more second edges corresponding to the one or more first edges; matching the model and the image; and adjusting the one or more second edges of the model based on the one or more first edges.

Abstract: The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, R3, X, Ar, Y and n are defined as in the specification and claims. The compounds of general formula (I) in the present invention, stereoisomers and pharmaceutically acceptable salts thereof can be used as Lp-PLA2 inhibitors for preventing, treating and/or ameliorating diseases associated with the activity of Lp-PLA2 enzyme.

Abstract: The present disclosure discloses a method for generating color medical image. The method for generating color medical image comprising: acquiring medical image data, segmenting at least one tissue in the medical image data, determining a combined color table from a combined color table database based on the at least one tissue; and generating a color medical image based on the combined color table. In some embodiments, the combined color table comprises data of color schemes for the segmented tissues.

Abstract: The present disclosure relates to an image processing method. The method may include: obtaining image data; reconstructing an image based on the image data, the image including one or more first edges; obtaining a model, the model including one or more second edges corresponding to the one or more first edges; matching the model and the image; and adjusting the one or more second edges of the model based on the one or more first edges.

Abstract: A method for image segmentation may include acquiring an image including a region of interest (ROI). The ROI has a first margin, the ROI includes a subregion, and the subregion has a second margin. The method may further include acquiring a first model according to the ROI, wherein the first model has a third margin. The method may further determine, based on the first margin and the third margin, a second model by matching the first model with the image, wherein the second model includes a sub-model, and the sub-model has a fourth margin. The method may further include determining, based on the second margin, a third model by adjusting the fourth margin of the sub-model in the second model. The method may further include segmenting the ROI according to the third model and generating a segmented ROI based on a result of the segmentation.

Abstract: The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, R3, X, Ar, Y and n are defined as in the specification and claims. The compounds of general formula (I) in the present invention, stereoisomers and pharmaceutically acceptable salts thereof can be used as Lp-PLA2 inhibitors for preventing, treating and/or ameliorating diseases associated with the activity of Lp-PLA2 enzyme.

Abstract: The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, R3, X, Ar, Y and n are defined as in the specification and claims. The compounds of general formula (I) in the present invention, stereoisomers and pharmaceutically acceptable salts thereof can be used as Lp-PLA2 inhibitors for preventing, treating and/or ameliorating diseases associated with the activity of Lp-PLA2 enzyme.

Abstract: A method for image segmentation may include acquiring an image including a region of interest (ROI). The ROI has a first margin, the ROI includes a subregion, and the subregion has a second margin. The method may further include acquiring a first model according to the ROI, wherein the first model has a third margin. The method may further determine, based on the first margin and the third margin, a second model by matching the first model with the image, wherein the second model includes a sub-model, and the sub-model has a fourth margin. The method may further include determining, based on the second margin, a third model by adjusting the fourth margin of the sub-model in the second model. The method may further include segmenting the ROI according to the third model and generating a segmented ROI based on a result of the segmentation.

Abstract: The present disclosure discloses a method for generating color medical image. The method for generating color medical image comprising: acquiring medical image data, segmenting at least one tissue in the medical image data, determining a combined color table from a combined color table database based on the at least one tissue; and generating a color medical image based on the combined color table. In some embodiments, the combined color table comprises data of color schemes for the segmented tissues.

Abstract: The present invention relates to pyrimidone compounds used as Lp-PLA2 inhibitors and pharmaceutical compositions thereof. The structure of the pyrimidone compounds is represented by general formula (I), wherein R1, R2, R3, X, Ar, Y and n are defined as in the specification and claims. The compounds of general formula (I) in the present invention, stereoisomers and pharmaceutically acceptable salts thereof can be used as Lp-PLA2 inhibitors for preventing, treating and/or ameliorating diseases associated with the activity of Lp-PLA2 enzyme.

Abstract: The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I), or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. In one embodiment, the compound is represented by Structural Formula (II), or a prodrug, isomer, ester, salt, hydrate, solvate or polymorph thereof. The present invention also provides a pharmaceutical composition comprising the compound of the invention and method of use thereof.

Abstract: A method and system for extracting coronary artery centerlines from 3D medical image volumes is disclosed. Heart chambers are segmented in a 3D volume. Coronary artery centerlines are initialized in the 3D volume coronary artery based on the segmented heart chambers. The coronary artery centerlines are locally refined based on a vesselness measure. A length of each coronary artery centerline is shrunk to verify that the coronary artery centerline is within a coronary artery. The coronary artery centerline is the extended using data-driven vessel tracing.

Abstract: The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I): or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. The present invention also provides a pharmaceutical composition comprising a compound of the invention and method of use thereof.