Abstract: Disclosed are a polypeptide vaccine coupled with a TLR7 agonist for novel coronavirus and the use thereof. Specifically, the present invention provides a vaccine polypeptide for novel coronavirus pneumonia based on the basis of the analytical study of the RBD sequence and structural information of the S protein of SARS-CoV-2, wherein the vaccine polypeptide has the following structural formula: Z-(J-U)n, where in the formula, Z, J, U, n, etc. are as defined in the description. Also provided in the present invention are a vaccine composition containing the vaccine polypeptide and the use thereof.

Abstract: Embodiments of three-dimensional (3D) memory devices having through stair contacts (TSCs) and methods for forming the same are disclosed. In an example, a 3D memory device includes a memory stack and a TSC. The memory stack includes a plurality of interleaved conductive layers and dielectric layers. Edges of the interleaved conductive layers and dielectric layers define a staircase structure on a side of the memory stack. The TSC extends vertically through the staircase structure of the memory stack. The TSC includes a conductor layer and a spacer circumscribing the conductor layer.

Abstract: A directly connected drill pipe applicable to extreme conditions includes a tool joint pin and a tool joint box, where an external pipe section is located on an external side of a threaded section of the tool joint pin, and an annular groove is formed between the external pipe section and the threaded section of the tool joint pin. An insertion section of the tool joint box can be inserted into the annular groove in a matched manner. A main shoulder of the tool joint pin is located at an end of the external pipe section, a main auxiliary shoulder of the tool joint pin is located on a bottom surface of the annular groove, and an auxiliary shoulder of the tool joint pin is located at a small end of the tool joint pin. The tool joint box has three corresponding shoulders which form a 3-stage sealing with the tool joint pin.

Abstract: The present disclosure relates to drug eluting stents, methods of making, using, and verifying long-term stability of the drug eluting stents, and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent. In one embodiment, a drug eluting stent may include a stent framework; a drug-containing layer; a drug embedded in the drug-containing layer; and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer. The drug-containing layer may have an uneven coating thickness. In addition or in alternative, the drug-containing layer may be configured to significantly dissolve/dissipate/disappear between 45 days and 60 days after stent implantation. Stents of the present disclosure may reduce, minimize, or eliminate patient risks associated with the implantation of a stent, including, for example, restenosis, thrombosis, and/or MACE.

Abstract: The disclosure relates to a micro gunsight, a small laser, a fine-tuning spring, a laser sight device inner core, a reset pin and a laser sight device. which includes a mounting slot that is matched with the gun card track. The mounting slot is composed of a fixed rail and a movable rail. The mounting slot is provided with a gunsight body, and inside the gunsight body is provided with a laser fine-tuning seat. A dual-light laser is installed inside the laser fine-tuning seat, and a fine-tuning mechanism is installed in the laser fine-tuning seat. There are multiple adapters at the bottom of the gunsight body, which are suitable for different Picatinny rails, making the installation position closer to the trigger guard, convenient for users to operate, and avoiding the problem of easy loosening of the front and rear positions of the sight device.

Abstract: A Super304H steel welding wire capable of resisting high-temperature creep and aging embrittlement, includes the following chemical components in percentage by mass: 0.04-0.1% of C, 0.4-1.5% of Mn, 7.5-12.5% of Ni, ?0.5% of Si, 17.0-19.0% of Cr, ?0.4% of Mo, 2.5-3.5% of Cu, 0.3-0.6% of Nb, 0.05-0.12% of N, ?0.01% of S, ?0.02% of P and the balance of Fe and other inevitable impurity elements. The welding wire can be used for welding of Super304H steel used in ultra super critical thermal power stations, has a weld being in a double-phase structure of austenite and a small amount of ferrite (volume fraction is 3-12%), and has good hot cracking resistance capability.

Abstract: An angle adjustment mechanism includes a hollow cylindrical fine adjustment seat (1), a hollow cavity of the fine adjustment seat (1) are provided with a tapered fine adjustment screw (3) and a mounting seat (2) having a tapered surface (201), the tapered fine adjustment screw (3) and the mounting seat (2) are opposed to each other along the axial direction, the tapered surface (201) of the mounting seat (2) is provided with four strip-shaped planes (202) evenly spaced in the circumferential direction, two adjacent strip-shaped planes (202) are overlapped with the tapered surfaces of two tapered fine adjustment screws (3) respectively, the tapered fine adjustment screw (3) can move forward or backward in a cavity formed by an inner wall of the fine adjustment seat (1) and the tapered surface (201) of the mounting seat (2) along a strip-shaped plane (202) that coincides with the tapered fine adjustment screw (3).

Abstract: A solar inner red dot sight includes a body, a power supply and a solar cell arranged on the body, a control circuit board and an LED light-emitting chip arranged on or in the body, a photoelectric sensor arranged on a side of the LED light-emitting chip, wherein the photoelectric sensor is used to collect illuminance signals of a shooting target or surroundings thereof; the control circuit board obtains power supplied to the LED light-emitting chip according to the signals of the solar cell and the illuminance signals of the photoelectric sensor, and compares the power with the solar energy, when the solar energy is less than the power energy, the control circuit board turns on the power supply to power the LED light-emitting chip; or when the solar signal is strong, the LED light emitting chip is powered by the solar cell only.

Abstract: An open airborne or vehicle-mounted sight, including a carrier and an inner red dot module carrier installed on the carrier. The inner red dot module carrier is installed on the top surface of the carrier by means of a pitch angle adjustment mechanism. An inner red dot module, including an LED light source capable of projecting graphic signs; the LED light source includes a point light source, a peripheral light source surrounding the point light source, and the peripheral light source is a discontinuous line light source.

Abstract: An LED mounting base, an adjustment mechanism with the LED mounting base and a red dot sighting device with the adjustment mechanism are provided in the present disclosure. The LED mounting base includes a sliding block base and a pedestal in which an LED chip is mounted at the middle of the front end surface thereof. A sliding slot parallel to the length direction of the pedestal is disposed on the front end surface of the sliding block base. One end of the sliding slot is a blind end, and the other end of the sliding slot is an open end. After the pedestal being disposed in the sliding slot, the front end surface of the pedestal is parallel to the front end surface of the sliding block base. The LED mounting base which is modular in design and more compact, is less affected by the gap. The resultant force generated when adjusted in the two-dimensional directions of up and down as well as the left and right is decomposed into a single direction.

Abstract: A directly connected drill pipe applicable to extreme conditions includes a tool joint pin and a tool joint box, where an external pipe section is located on an external side of a threaded section of the tool joint pin, and an annular groove is formed between the external pipe section and the threaded section of the tool joint pin. An insertion section of the tool joint box can be inserted into the annular groove in a matched manner. A main shoulder of the tool joint pin is located at an end of the external pipe section, a main auxiliary shoulder of the tool joint pin is located on a bottom surface of the annular groove, and an auxiliary shoulder of the tool joint pin is located at a small end of the tool joint pin. The tool joint box has three corresponding shoulders which form a 3-stage sealing with the tool joint pin.

Abstract: A reflective inner red dot sight optical system with improved monochromaticity and concealment, a two-light three-color optical system, and a sight thereof. The reflective inner red dot sight optical system comprises an LED chip and a lens for reflecting light emitted from the LED chip. A filter provided with a narrow-band interference filter coating is provided near the LED chip and located between the LED chip and the lens. The filter is used to filter out wide band waves not in the central wavelength of the light reflected from the lens into the eye, thereby improving the monochromaticity of the light entering the eye.

Abstract: The present disclosure relates to drug eluting stents, methods of making, using, and verifying long-term stability of the drug eluting stents, and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent. In one embodiment, a drug eluting stent may include a stent framework; a drug-containing layer; a drug embedded in the drug-containing layer; and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer. The drug-containing layer may have an uneven coating thickness. In addition or in alternative, the drug-containing layer may be configured to significantly dissolve/dissipateldisappear between 45 days and 60 days after stent implantation. Stents of the present disclosure may reduce, minimize, or eliminate patient risks associated with the implantation of a stent, including, for example, restenosis, thrombosis, and/or MACE.

Abstract: An angle adjustment mechanism includes a hollow cylindrical fine adjustment seat (1), a hollow cavity of the fine adjustment seat (1) are provided with a tapered fine adjustment screw (3) and a mounting seat (2) having a tapered surface (201), the tapered fine adjustment screw (3) and the mounting seat (2) are opposed to each other along the axial direction, the tapered surface (201) of the mounting seat (2) is provided with four strip-shaped planes (202) evenly spaced in the circumferential direction, two adjacent strip-shaped planes (202) are overlapped with the tapered surfaces of two tapered fine adjustment screws (3) respectively, the tapered fine adjustment screw (3) can move forward or backward in a cavity formed by an inner wall of the fine adjustment seat (1) and the tapered surface (201) of the mounting seat (2) along a strip-shaped plane (202) that coincides with the tapered fine adjustment screw (3).

Abstract: A solar inner red dot sight, includes a body, a power supply and a solar cell arranged on the body, a control circuit board and an LED light-emitting chip arranged on or in the body, a photoelectric sensor arranged on a side of the LED light-emitting chip, wherein the photoelectric sensor is used to collect illuminance signals of a shooting target or surroundings thereof target; the control circuit board obtains power supplied to the LED light-emitting chip according to the signals of the solar cell and the illuminance signals of the photoelectric sensor, and compares the power with the solar energy, when the solar energy is less than the power energy, the control circuit board turns on the power supply to power the LED light-emitting chip; or when the solar signal is strong, the LED light emitting chip is powered by the solar cell only.

Abstract: A directly connected drill pipe applicable to extreme conditions includes a tool joint pin and a tool joint box, where an external pipe section is located on an external side of a threaded section of the tool joint pin, and an annular groove is formed between the external pipe section and the threaded section of the tool joint pin. An insertion section of the tool joint box can be inserted into the annular groove in a matched manner. A main shoulder of the tool joint pin is located at an end of the external pipe section, a main auxiliary shoulder of the tool joint pin is located on a bottom surface of the annular groove, and an auxiliary shoulder of the tool joint pin is located at a small end of the tool joint pin. The tool joint box has three corresponding shoulders which form a 3-stage sealing with the tool joint pin.

Abstract: The present disclosure relates to drug eluting stents, methods of making, using, and verifying long-term stability of the drug eluting stents, and methods for predicting long term stent efficacy and patient safety after implantation of a drug eluting stent. In one embodiment, a drug eluting stent may include a stent framework; a drug-containing layer; a drug embedded in the drug-containing layer; and a biocompatible base layer disposed over the stent framework and supporting the drug-containing layer. The drug-containing layer may have an uneven coating thickness. In addition or in alternative, the drug-containing layer may be configured to significantly dissolve/dissipate/disappear between 45 days and 60 days after stent implantation. Stents of the present disclosure may reduce, minimize, or eliminate patient risks associated with the implantation of a stent, including, for example, restenosis, thrombosis, and/or MACE.

Abstract: Embodiments of three-dimensional (3D) memory devices having through stair contacts (TSCs) and methods for forming the same are disclosed. In an example, a 3D memory device includes a memory stack and a TSC. The memory stack includes a plurality of interleaved conductive layers and dielectric layers. Edges of the interleaved conductive layers and dielectric layers define a staircase structure on a side of the memory stack. The TSC extends vertically through the staircase structure of the memory stack. The TSC includes a conductor layer and a spacer circumscribing the conductor layer.

Abstract: An optical system for assisting image positioning. The system comprises a light source (1), and further comprises a dot pattern or an interface beam-splitting pattern which is arranged on a light-emergent light path of the light source (1) and generates an interface beam-splitting projection light ray for indicating a text or an image after being projected by emergent light of the light source (1). By means of a combination of a light source (1) and a dot pattern or an interface beam-splitting pattern, a word line, a cross line, or the other patterns which can generate a beam-splitting interface can be projected. Furthermore, by virtue of a DOE moulding lens, of which an emergent face is a spherical face or an aspherical face, a specific linear light beam or the other patterns which can generate the beam-splitting interface are generated.