Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody binds HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.

Abstract: This application provides a pathological section image processing method performed by a computer device. The method includes: obtaining stained images of a pathological section after cell membrane staining; determining cell nucleus positions of cancer cells in a stained image under an ith field of view in the n fields of view; generating a cell membrane description result of the stained image under the ith field of view, the cell membrane description result being used for indicating completeness and staining intensity of the cell membrane staining; determining quantities of cells of types in the stained image under the ith field of view according to the cell nucleus positions and the cell membrane description result; and determining an analysis result of the pathological section according to quantities of the cells of types in the stained images under the n fields of view.

Abstract: The present disclosure relates to a data processing method, a data processing apparatus, and related products. The data processing apparatus includes an address determining unit and a data storage unit. The address determining unit is configured to determine a source data address and a plurality of discrete destination data addresses of data corresponding to a processing instruction when the decoded processing instruction is a discrete store instruction, where the source data address may include continuous data addresses.

Abstract: A data processing method and apparatus, and a related product. The data processing method comprises: when a decoded processing instruction is a vector extension instruction, determining a source data address, a destination data address and an extension parameter of data corresponding to the processing instruction; according to the extension parameter, extending first vector data of the source data address, so as to obtain extended second vector data; storing the second vector data to the destination data address, wherein the source data address and the destination data address comprise consecutive data addresses. Vector extension and storage are implemented by means of an extension parameter in a vector extension instruction, so as to obtain extended vector data, thereby simplifying processing, and reducing data overhead.

Abstract: A flash device includes user storage space for storing user data and over provisioning space for garbage collection within the flash device. The flash device receives an operation instruction, and then performs an operation on user data stored in the user storage space based on the operation instruction. Further, the flash device identifies a changed size of user data after performing the operation. Based on the changed size of data, a target adjustment parameter is identified. Further, the flash device adjusts the capacity of the over provisioning space according to the target adjustment parameter.

Abstract: Provided are a system and method for implementing an incremental data comparison. The system includes: a synchronization T environment, a simulation F environment, a simulation tool, a memory database, a comparison tool and a result database. The T environment includes a synchronization environment core application, a traditional commercial database, an incremental synchronization tool and a synchronization environment distributed database. The F environment includes a simulation environment core application and a simulation environment distributed database. The simulation tool is configured to play back a T environment service and an F environment service. The memory database is configured to store a mapping relationship between message values of the T and F environment. The comparison tool is configured to compare data in the T and F environment according to the mapping relationship between the message values.

Abstract: An amphibious robot for in-service inspection of drainage pipelines and a control method thereof are provided. The robot includes a robot body, a detection module for detecting environmental state and pose information of robot itself, a propulsion module including a car-like propulsion module and a ship-like propulsion module for controlling robot movement, a structure conversion module for realizing the conversion between the two modes, a ground terminal controller for remote information monitoring and issuing instructions, a mobile terminal controller for receiving instructions and controlling robot movement and structure conversion, and a power module.

Abstract: Disclosed herein is a liquid crystal mixture applied in light modulating devices, comprising: component A comprised of one or more compounds selected from the group of compounds of formula (I), component B comprised of one or more compounds selected from the group of compounds of formula (II), and component C comprised of one or more chiral compounds. Also disclosed is a light modulating device containing the liquid crystal mixture, wherein the liquid crystal mixture has higher stability of electrical performance and the light modulating device has improved optical performance.

Abstract: This application provides a task migration system and method. The system includes a first terminal and a second terminal. The second terminal runs a first application. The first terminal opens a recent task interface after receiving a user operation, where the recent task interface includes an identifier of the second terminal; after receiving a user operation performed on the identifier of the second terminal, displays, in the recent task interface, at least one task card corresponding to an application run by the second terminal in the background; and after receiving a user operation performed on a first task card corresponding to the first application, runs the first application, and displays a first user interface of the first application.

Abstract: A detection circuit for instantaneous voltage drop and an on-board diagnostic system. The detection circuit comprises two RC circuits, each of the RC circuits comprises a first resistor, a second resistor, and an energy storage capacitor; a first end of the first resistor is used for receiving a to-be-detected voltage, and a second end thereof is connected to a first end of the second resistor; the energy storage capacitor is connected in parallel with the second resistor; the first end of the second resistor forms an output end of the RC circuit, and the output end is connected to an input end of the comparator; an output end of the comparator is connected to the determination unit; in the two RC circuits, the resistance ratios of the second resistors to the first resistors are different, the capacitances of the energy storage capacitors are different.

Abstract: For the problem of difficult roof anchor withdrawal at the end of a working face, a static crushing directional anchor withdrawal method at the end of a large-mining-height working face is provided. The method includes the following steps: designing key parameters of boreholes for static crushing, including a borehole position, a spacing between boreholes, a borehole depth, and a borehole diameter at the end of a working face; then determining parameters of a static crushing agent grouting technology device for the construction of a static crushing process; and carrying out an anchor withdrawal operation at the end.

Abstract: A programmable semiconductor device contains a wireless communication block (“WCB”) capable of facilitating wirelessly field programmable gate array (“FPGA”) programming download as well as functional logic implementation. In one aspect, WCB detects an FPGA access request for initiating an FPGA reconfiguration from a remote system via a wireless communications network. Upon receiving a configuration bitstream for programming the FPGA via the wireless communications network, the configuration bitstream is forwarded from WCB to a configuration download block (“CDB”) for initiating a configuration process. CDB subsequently programs at least a portion of configurable logic blocks (“LBs”) in FPGA in response to the configuration bitstream.

Abstract: A CD70 antibody and a chimeric antigen receptor (CAR) that can specifically bind to a CD70 protein. The CAR comprises a CD70 binding domain, a transmembrane domain, a costimulatory domain, and an intracellular signaling domain. Further disclosed is an application of the antibody and the CAR for treating diseases or conditions related to CD70 expression.

Abstract: The present invention relates to a strategy for combining a berberine analog with a JAK inhibitor in the treatment of inflammatory diseases of the gastrointestinal tract. Specifically, provided by the present invention is a pharmaceutical composition containing the berberine analog and the JAK inhibitor, and a use thereof in the treatment of inflammatory diseases of the gastrointestinal tract. The composition may exhibit an improved effect over the use of berberine or the JAK inhibitor alone.

Abstract: The present invention relates to a codrug that cleaved in the gut, preparation therefor, and a use thereof. Specifically, provided is a codrug compound in formula I. Also provided are a method of using the present compound for the treatment of gastrointestinal tract autoimmune diseases, inflammatory diseases, and cancers, as well as a method and an intermediate for preparing the present compound.

Abstract: The present invention discloses T-cell receptor of HLA-A11-restricted hepatitis B virus HBc 141-151 epitope peptide and applications thereof. The T cell receptor comprises an ? chain and ? chain; the ? chain comprises three complementarity determining regions with amino acid sequences shown in positions 48 to 53, positions 71 to 77 and positions 112 to 121 of SEQ ID NO. 2, respectively; the ? chain comprises three complementarity determining regions with amino acid sequences shown in positions 46 to 50, positions 68 to 73 and positions 111 to 122 of SEQ ID NO. 4, respectively. Experiments demonstrated that the T cell receptor exhibits both HBV polypeptide epitope-dependent activation and proliferation ability and also exhibits an ability to kill target cells both in vivo and in vitro.

Abstract: A digital twin modeling method to assemble a robotic teleoperation environment, including: capturing images of the teleoperation environment; identifying a part being assembled; querying the assembly assembling order to obtain a list of assembled parts according to the part being assembled; generating a three-dimensional model of the current assembly from the list and calculating position pose information of the current assembly in an image acquisition device coordinate system; loading a three-dimensional model of the robot, determining a coordinate transformation relationship between a robot coordinate system and an image acquisition device coordinate system; determining position pose information of the robot in an image acquisition device coordinate system from the coordinate transformation relationship; determining a relative positional relationship between the current assembly and the robot from position pose information of the current assembly and the robot in an image acquisition device coordinate syste

Abstract: A detection circuit for instantaneous voltage drop and an on-board diagnostic system. The detection circuit comprises two RC circuits, each of the RC circuits comprises a first resistor, a second resistor, and an energy storage capacitor; a first end of the first resistor is used for receiving a to-be-detected voltage, and a second end thereof is connected to a first end of the second resistor; the energy storage capacitor is connected in parallel with the second resistor; the first end of the second resistor forms an output end of the RC circuit, and the output end is connected to an input end of the comparator; an output end of the comparator is connected to the determination unit; in the two RC circuits, the resistance ratios of the second resistors to the first resistors are different, the capacitances of the energy storage capacitors are different.

Abstract: An on-board diagnostics device (10) and system, a testing method and a non-transitory computer-readable storage medium are disclosed. The on-board diagnostics device (10) may include: a master control module (11), a controller (12), a selection module (13), and a plurality of protocol transceivers (14), where the selection module (13) is connected to some or all of protocol transceivers (14); the master control module (11) is configured for controlling the controller (12), the selection module (13) and the protocol transceivers (14), and performing data transceiving on the basis of the selected protocol transceivers (14) and corresponding pins; the controller (12) is configured for receiving an external control signal and controlling the selection module (13) according to the external control signal; the selection module (13) is configured for switching between different protocol transceivers (14) and the pins; and the protocol transceivers (14) are configured for data transceiving of supported protocols.

Abstract: Water outlet valve structure and a humidifier having the same. Opening or closing of the water outlet valve structure is controlled by a control structure. The water outlet valve structure includes a flow channel including an inlet and an outlet. The control structure is capable of sealing or opening the outlet of the flow channel. The outlet of the flow channel is capable of being sealed or opened by the control structure of the water outlet valve structure, to control the open and close of the flow channel, thereby simplifying the water outlet valve structure. In a further aspect, since only the outlet is sealed, specific requirements for the structure of the control structure are relatively low, thereby allowing the control structure to be simplified.