Abstract: A method and system to optimize the parameters of a robot used in an assembly process. The assembly process is categorized based on its nature which may be cylindrical, radial and multi-stage insertion. The search pattern and search parameters are specified. The parameters are optimized and the optimized parameter set are verified and when a predetermined criteria such as assembly cycle time set and/or success rate is met the optimization process stops. When the optimization stops the verified parameters are used to cause the robot to perform the categorized assembly process. If the parameters do not meet the predetermined criteria, another round of optimization using the same or other parameters can be performed.

Abstract: This invention addresses the clinical problem of how to optimize biological cell based therapies, such as stem cell therapy. Currently, cell therapies administered by intravenous, intra-arterial, and/or direct tissue injection are limited by the lack of clinically available imaging methods to detect the in vivo fate of the administered cells. There are many efforts underway to develop imaging strategies for stem cells in vivo, including radionuclide and MRI-based approaches. However, these approaches are limited by potential safety issues (e.g. radioactive exposure of stem cells, toxicity of iron particles used for MRI) and difficulty in serial tracking due to complex instrumentation and/or the requirement for repetitive radiation exposure.

Abstract: A robot is used to repeatedly assemble part during a continuous production run of parts to be assembled. There are parameters of the robot associated with the assembly. These parameters are used to assemble the parts. Simultaneously with that repeated assembly the robot parameters are optimized. The parts to be assembled have a starting position for the assembly and the simultaneous optimization of the robot assembly parameters also includes the learning of the starting position. The robot assembly parameters can be optimized in a predefined manner. The optimized parameters can then be verified and the optimized and verified robot assembly parameters may then be used in place of the parameters of the robot associated with the parts assembly along with the learned starting position.

Abstract: There is described a method and system for developing for an automation process a screen viewable on a target computer that has user interface objects. A development computer has a set of common design time components from a general purpose software development kit that also has a databinding facility and a set of customization components. Those components have an interface that allows access to the available for use automation process data objects and a process object picker that act as a user interface to the databinding facility to allow the browsing of a subset of the available for use data objects and selecting of one or more of the objects in the subset for binding by the databinding facility either to one or more members of the user interface objects or one or more of the user interface objects or a combination of the same.

Abstract: The present invention is directed to a method and apparatus for developing a metadata-infused software program for controlling a device, such as a robot. A first library of software segments with metadata and a second library of script documents are provided. A part program wizard uses a script document selected from the second library to display queries on a screen of an interface device. Using input information received in response to the queries, the part program wizard selects and combines software segments from the first library to produce the metadata-infused software program. The metadata identifies the selected software segments and includes statuses of the selected software segments. A graphical representation of the metadata infused software program is displayed on the screen and conveys the statuses of the software segments. A deployment wizard is utilized to teach data points for the metadata-infused software program.

Abstract: A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.

Abstract: A robot having a force sensor and a tool fixture for operating on a workpiece that may have a complex surface contour is programmed by an operator first teaching the robot by a suitable technique such as lead through teaching a few gross points of the contour. These points, known as guiding points, are used to generate a program to be followed by the robot under the control of the robot controller and using force control during which the robot finalizes the guiding points and teaches one or more points on the contour intermediate adjacent guiding points. The controller or other computing device uses the points so taught to generate the path the robot tool fixture will follow when the tool is to operate on the workpiece.

Abstract: Carbon nanoflakes, methods of making the nanoflakes, and applications of the carbon nanoflakes are provided. In some embodiments, the carbon nanoflakes are carbon nanosheets, which are less than 2 nm thick. The carbon nanoflakes may be made using RF-PECVD. Carbon nanoflakes may be useful as field emitters, for hydrogen storage applications, for sensors, and as catalyst supports.

Abstract: An industrial robot that uses a simulated force vector to allow a work piece held by the robot end effector to be mated with a work piece whose location and orientation is not precisely known to the robot. When the end effector makes contact with the location and orientation in which the other work piece is held the robot provides a velocity command to minimize the force of the contact and also provides a search pattern in all directions and orientations to cause the end effector to bring the work piece it is holding in contact with the other work piece. The search pattern and the velocity command are continued until the two work pieces mate.

Abstract: Both vision and force control are used to program a robot so that a tool having a tip can follow a desired path visibly marked on a workpiece when the tool is to perform work on the workpiece. There is a force sensor, a camera positioned to view the visibly marked path and a computing device. When the tool tip is in controlled contact with an area of the workpiece that includes the desired path, the camera and the force sensor each provide information to the computing device. The information is used to develop a program to move the robot to cause the tool tip to follow the desired path when the tool is to perform work on the workpiece. The tool can move in relation to the workpiece and the camera is mounted on the robot or the workpiece moves in relation to the stationary camera and tool.

Abstract: An industrial robot that uses a simulated force vector to allow a work piece held by the robot end effector to be mated with a work piece whose location and orientation is not precisely known to the robot. When the end effector makes contact with the location and orientation in which the other work piece is held the robot provides a velocity command to minimize the force of the contact and also provides a search pattern in all directions and orientations to cause the end effector to bring the work piece it is holding in contact with the other work piece. The search pattern and the velocity command are continued until the two work pieces mate.

Abstract: An industrial robot that has uses a simulated force vector to allow a work piece held by the robot end effector to be mated with a work piece whose location and orientation is not precisely known to the robot. When the end effector makes contact with the location and orientation in which the other work piece is held the robot provides a velocity command to minimize the force of the contact and also provides a search pattern in all directions and orientations to cause the end effector to bring the work piece it is holding in contact with the other work piece. The search pattern and the velocity command are continued until the two work pieces mate.

Abstract: An accelerometer is mounted on a robot to monitor movement of a tool assembly attached to the robot end effector for safety monitoring purposes. The accelerometer provides an output signal to the robot controller which the controller uses to monitor the robot movement and stop that movement when a predetermined values of acceleration, speed and distance are detected during lead-through teaching of the robot. A handle can be attached to the robot end effector and the accelerometer can be mounted on the handle.

Abstract: The present invention is directed to a method and apparatus for developing a metadata-infused software program for controlling a device, such as a robot. A first library of software segments with metadata and a second library of script documents are provided. A part program wizard uses a script document selected from the second library to display queries on a screen of an interface device. Using input information received in response to the queries, the part program wizard selects and combines software segments from the first library to produce the metadata-infused software program. The metadata identifies the selected software segments and includes statuses of the selected software segments. A graphical representation of the metadata infused software program is displayed on the screen and conveys the statuses of the software segments. A deployment wizard is utilized to teach data points for the metadata-infused software program.

Abstract: A robot machining with a flexible manipulator has an end effector which may either hold the tool to perform the machining or the work piece to be machined. A signal representative of a force applied by said tool to said work piece is used to control either the relative motion between the tool and the work piece to give a controlled material removal rate (CMRR) or the relative position between the tool or the work piece to provide deformation compensation or both CMRR and deformation compensation. A force sensor provides the signal for deformation compensation. For CMRR the signal may be obtained from either a force sensor or the current flowing in the motor of the robot's spindle. The force sensor can be mounted either on the robot or together with either the tool or work piece adjacent to the robot.

Abstract: An industrial robot that has uses a simulated force vector to allow a work piece held by the robot end effector to be mated with a work piece whose location and orientation is not precisely known to the robot. When the end effector makes contact with the location and orientation in which the other work piece is held the robot provides a velocity command to minimize the force of the contact and also provides a search pattern in all directions and orientations to cause the end effector to bring the work piece it is holding in contact with the other work piece. The search pattern and the velocity command are continued until the two work pieces mate.

Abstract: A method and apparatus for calibrating a sensor for determination of the concentration of a sterilant, e.g., hydrogen peroxide vapor, in a sterilization system. This invention provides a method for calibrating a sensor that is used for measuring the quantity of a sterilant in a system for delivering the sterilant, the method comprising the steps of: (a) generating reference calibration data, the reference calibration data showing a mathematical relationship between a measurable parameter, e.g. voltage, and a quantity of the sterilant, e.g.

Abstract: A method and apparatus for calibrating a sensor for determination of the concentration of a sterilant, e. g., hydrogen peroxide vapor, in a sterilization system.

Abstract: A method and apparatus for determining the dispersibility grade of particulate material by means of an image processing technique that employs machine vision. In one aspect, this invention provides a method for grading the dispersibility of particulate material, the method comprising the steps of: (a) obtaining an image, in digitized form, of a sample comprising reconstituted particulate material; (b) performing a series of image processing steps to determine the presence and magnitude of blobs; (c) performing a blob analysis to obtain data relating to the distribution of the particulate material in the sample; (d) comparing the result of the blob analysis with data in a database; and (e) determining the grade of said particulate material by means of the comparison. The sample of particulate material, which is typically in the form of a powder, is reconstituted preferably by means of agitating a container filled with the sample.