Abstract: The present invention relates to use of homoharringtonine in manufacturing a drug for treating an acquired immunodeficiency syndrome. A homoharringtonine compound is prepared as a drug for treating the acquired immunodeficiency syndrome and is applied to the treatment of the acquired immunodeficiency syndrome. The homoharringtonine compound can significantly reduce the programmed ribosomal frameshifting (PRF) efficiency of the mRNA of HIV-1 during the translation of a Gag-Pol fusion protein to substantially decrease the translation efficiency of the Pol protein. Therefore, the cell fails to produce protease, integrase, and reverse transcriptase obtained via Pol splicing such that a virus cannot be packaged effectively, which eventually leads to a sharp decline in yield of the virus. Therefore, the compound of the present invention has a good anti-HIV effect.

Abstract: A method for preparing a thin-walled composite pipe is provided, in which an AlN particle/zinc-aluminum 27 (AlNp/ZA27) composite billet is subjected to multi-pass reciprocating extrusion at 250-350° C., and then loaded into a pipe extrusion die. The composite billet is heated with the temperature being in an ascending gradient distribution (within a range of 250-350° C.) along an extrusion direction from the billet to an outlet of the die, then kept a preset temperature for a period of time, and finally extruded at a rate of 0.1-0.5 mm/s to obtain the thin-walled composite pipe. A thin-walled composite pipe prepared by this method is also provided, including an AlN particle and a ZA27 alloy.

Abstract: A method for preparing a Zn—Mg—Ca—Sr alloy, in which an as-cast Zn—Mg—Ca—Sr alloy is subjected to homogenization, and a boron nitride lubricant is sprayed on a surface of the as-cast Zn—Mg—Ca—Sr alloy and an inner cavity surface of a die. The as-cast Zn—Mg—Ca—Sr alloy is put into the die, and subjected to heating and 8-pass reciprocating extrusion to obtain the desired Zn—Mg—Ca—Sr alloy with high strength and high toughness, where the extrusion speed is stagewise controlled to realize stagewise variable-extrusion speed reciprocating extrusion. This application also provides a biodegradable medical implant material including a Zn—Mg—Ca—Sr alloy prepared by such method.

Abstract: A method of preparing biodegradable Zn—Mg—Bi zinc alloy includes: melting magnesium under an inert atmosphere to obtain a magnesium melt; adding bismuth particles to the magnesium melt followed by reaction under stirring and heat preservation treatment to obtain a Mg—Bi alloy melt; allowing the Mg—Bi alloy melt to stand in a furnace; subjecting the Mg—Bi alloy melt to refining, slagging-off, casting and demoulding to obtain Mg-50 wt. % Bi alloy ingot; melting zinc to obtain a zinc melt; adding the Mg-50 wt. % Bi alloy ingot and pure magnesium or pure bismuth followed by heating to a preset temperature, stirring and heat preservation to obtain a Zn—Mg—Bi alloy melt; allowing the Zn—Mg—Bi alloy melt to stand in a furnace followed by refining, slagging-off, casting and demoulding to obtain the biodegradable Zn—Mg—Bi zinc alloy.

Abstract: A method of preparing biodegradable Zn—Mg—Bi zinc alloy includes: melting magnesium under an inert atmosphere to obtain a magnesium melt; adding bismuth particles to the magnesium melt followed by reaction under stirring and heat preservation treatment to obtain a Mg—Bi alloy melt; allowing the Mg—Bi alloy melt to stand in a furnace; subjecting the Mg—Bi alloy melt to refining, slagging-off, casting and demoulding to obtain Mg-50 wt. % Bi alloy ingot; melting zinc to obtain a zinc melt; adding the Mg-50 wt. % Bi alloy ingot and pure magnesium or pure bismuth followed by heating to a preset temperature, stirring and heat preservation to obtain a Zn—Mg—Bi alloy melt; allowing the Zn—Mg—Bi alloy melt to stand in a furnace followed by refining, slagging-off, casting and demoulding to obtain the biodegradable Zn—Mg—Bi zinc alloy.

Abstract: A device for preparing ultra-high purity zinc based on intelligently-controlled zone melting, including a slide platform connected with a screw through a servo control system to control movement of a heating-cooling device. A quartz tube is provided inside an induction heater to protect a melting zone. An infrared thermometer is connected to the heater, and configured to monitor temperature within the melting zone, and control power of the heater. A ring magnetic stirrer with non-contact circumferential rotation cooperates with coil to stir zinc melt. A water-cooling copper jacket is connected to two ends of the heater to cool a zinc bar, and its water inlet and outlet are connected with a water chiller. The infrared thermometer monitors temperature of the zinc bar and controls water flow of the cooling system. A lifting device is connected with a base cabinet to change inclined angle of the zinc bar.

Abstract: A plate heat exchanger includes a number of first heat exchange plates and a number of second heat exchange plates. The plate heat exchanger has a first inter-plate channel and a second inter-plate channel. The first inter-plate channel is located between a front surface of the second heat exchange plate and an adjacent first heat exchange plate. The second inter-plate channel is located between a back surface of the second heat exchange plate and another adjacent first heat exchange plate. The first heat exchange plate has a first flat joint portion and a second flat joint portion. The front surface of the second flat joint portion is spaced apart from an adjacent first flat joint portion. The plate heat exchanger includes at least one connection portion connecting the front surface of the second flat joint portion and the adjacent first flat joint portion.

Abstract: A plate heat exchanger includes a number of first heat exchange plates and a number of second heat exchange plates. The plate heat exchanger has a first inter-plate channel and a second inter-plate channel. The first inter-plate channel is located between a front surface of the second heat exchange plate and an adjacent first heat exchange plate. The second inter-plate channel is located between a back surface of the second heat exchange plate and another adjacent first heat exchange plate. The first heat exchange plate has a first flat joint portion and a second flat joint portion. The front surface of the second flat joint portion is spaced apart from an adjacent first flat joint portion. The plate heat exchanger includes at least one connection portion connecting the front surface of the second flat joint portion and the adjacent first flat joint portion.

Abstract: A device for preparing ultra-high purity zinc based on intelligently-controlled zone melting, including a slide platform connected with a screw through a servo control system to control movement of a heating-cooling device. A quartz tube is provided inside an induction heater to protect a melting zone. An infrared thermometer is connected to the heater, and configured to monitor temperature within the melting zone, and control power of the heater. A ring magnetic stirrer with non-contact circumferential rotation cooperates with coil to stir zinc melt. A water-cooling copper jacket is connected to two ends of the heater to cool a zinc bar, and its water inlet and outlet are connected with a water chiller. The infrared thermometer monitors temperature of the zinc bar and controls water flow of the cooling system. A lifting device is connected with a base cabinet to change inclined angle of the zinc bar.

Abstract: A high-thermal conductivity composite material is AlNp/ZA27 composite material, including 2%, 4%, 6%, or 8% by volume of aluminum nitride (AlN) ceramic particles and zinc-aluminium-27 (ZA27) alloy. The ZA27 alloy includes 70.52-71.08% by weight of Zn, 25.58˜27.65% by weight of Al, 1.27˜3.45% by weight of Cu, and 0.50% or less by weight of Mg. In the preparation of the high-thermal conductivity composite material, an as-cast AlNp/ZA27 composite material is subjected to homogenizing annealing and reciprocating extrusion.

Abstract: A biodegradable Zn—Mg—Bi zinc alloy and a preparation method thereof. The method including: melting magnesium under an inert atmosphere to obtain a magnesium melt; adding bismuth particles to the magnesium melt followed by reaction under stirring and heat preservation treatment to obtain a Mg—Bi alloy melt; allowing the Mg—Bi alloy melt to stand in a furnace; subjecting the Mg—Bi alloy melt to refining, slagging-off, casting and demoulding to obtain Mg-50 wt. % Bi alloy ingot; melting zinc to obtain a zinc melt; adding the Mg-50 wt. % Bi alloy ingot and pure magnesium or pure bismuth followed by heating to a preset temperature, stirring and heat preservation to obtain a Zn—Mg—Bi alloy melt; allowing the Zn—Mg—Bi alloy melt to stand in a furnace followed by refining, slagging-off, casting and demoulding to obtain the biodegradable Zn—Mg—Bi zinc alloy.

Abstract: Disclosed are a tripeptide epoxyketone compound, a preparation method thereof, and a use thereof in the preparation of anti-tumor drugs.

Abstract: Disclosed are a tripeptide epoxyketone compound, a preparation method thereof, and a use thereof in the preparation of anti-tumor drugs.