Abstract: The disclosure provides methods and kits for preparing a protein analyte for characterization. The method comprises pretreating a protein analyte in the presence of a magnetic bead in a changing magnetic field; and enzymatically digesting the protein analyte with an endopeptidase enzyme to provide a plurality of peptides for analysis by, for example, LC-MS/MS. The process can be performed in a single tube without the need for desalting or buffer exchange, in less than 2 hours.

Abstract: A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.

Abstract: A magnetic particle is disclosed. The magnetic particle comprises a magnetic material having a maximum field strength in a range of from about 20 emu/g to about 250 emu/g and a remanence in a range of from about 0 emu/g to about 30 emu/g. The magnetic particle further comprises an outer surface containing a ligand. The ligand interacts with an analyte of interest in the sample solution.

Abstract: A heat dissipation system for a smart piano may include a heat dissipation driver, a heat dissipation device, a sensor, a protection circuit and a hardware processor. The sensor may be configured to detect a thermal parameter of an execution device of the smart piano. The protection circuit may be configured to analyze the thermal parameter to generate a protection signal. The hardware processor may be configured to determine a preset algorithm, generate a control signal according to the protection signal and the preset algorithm, and control a heat dissipation condition of the smart piano. The controlling the heat dissipation condition of the smart piano may include control an operation condition of the execution device and/or the heat dissipation device. The controlling may include controlling an output power of the execution device and/or the heat dissipation device.

Abstract: The disclosed embodiments provide a system that forms a three-dimensional (3D) nanostructure through 3D printing. During operation, the system performs a 3D printing operation that uses multiple passes of a scanning probe microscope (SPM) tip to deliver an ink to form the 3D nanostructure, wherein the ink includes both a positively charged polyelectrolyte (PE) and a negatively charged PE. While delivering the ink, the SPM tip is loaded with the ink and moved to a target location to deposit the ink. Finally, after the multiple passes are complete, the system cures the 3D nanostructure to remove excess positive or negative charges from the 3D nanostructure.

Abstract: A heat dissipation system for a smart piano may include a heat dissipation driver, a heat dissipation device, a sensor, a protection circuit and a hardware processor. The sensor may be configured to detect a thermal parameter of an execution device of the smart piano. The protection circuit may be configured to analyze the thermal parameter to generate a protection signal. The hardware processor may be configured to determine a preset algorithm, generate a control signal according to the protection signal and the preset algorithm, and control a heat dissipation condition of the smart piano. The controlling the heat dissipation condition of the smart piano may include control an operation condition of the execution device and/or the heat dissipation device. The controlling may include controlling an output power of the execution device and/or the heat dissipation device.

Abstract: The disclosed embodiments provide a system that forms a three-dimensional (3D) nanostructure through 3D printing. During operation, the system performs a 3D printing operation that uses multiple passes of a scanning probe microscope (SPM) tip to deliver an ink to form the 3D nanostructure, wherein the ink includes both a positively charged polyelectrolyte (PE) and a negatively charged PE. While delivering the ink, the SPM tip is loaded with the ink and moved to a target location to deposit the ink. Finally, after the multiple passes are complete, the system cures the 3D nanostructure to remove excess positive or negative charges from the 3D nanostructure.