Abstract: Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders.

Abstract: Described herein are novel enzyme inhibitors. In some embodiments the enzyme inhibitors are integrase inhibitors, particularly HIV integrase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV integrase as a method of treating or preventing HIV, AIDS or related disorders.

Abstract: This invention disclosed a freezer; and it's control method. The freezer includes the casing and the top board, on which a pad for placing wine cups and bottles and for easy wine pouring is equipped. There is a fast cooling chamber at the ventilation opening of the freezer, and a clapboard to adjust temperature is placed in the freezer, dividing the freezer into two chambers vertically. Air return openings are equipped above and beneath the clapboard. The said fast cooling chamber includes an air outlet pipe. The pipe is fixed on the wall of the freezer, just wrapping the ventilation opening. The said clapboard to adjust temperature includes a board, sealed with tapes at both front and back, making the front part joint the glass door and the back part joint the internal wall of the freezer. At the same time, the air return opening can be open or closed dependent on need to form different temperature control of the fast cooling chamber and the two chambers.