Abstract: A core device of optical isolator comprises a polarizer and a polarization-rotating device, which are integrated together as a modularized device. The modularized core device can be combined with other optical components to provide optical isolators of desired characteristics. With the modularized core device, the assembling of optical isolator is simplified and combination with other component is enhanced, thereby extending the applications of the core device.

Abstract: A luminometer includes a movable carrier carrying a number of luminescence collectors arranged in an array for simultaneously detecting the same number of samples received in multiple wells defined in a microplate. An optic fiber optically couples each luminescence detector to an associated charge-coupled device whereby a luminescence signal emitted from each sample is transmitted to the charge-coupled device and converted thereby into a corresponding electric signal. The charge-coupled devices are isolated from each other by partitions, which eliminate undesired interference among the luminescence signals transmitted to the charge-coupled device. A driving unit is provided to move the carrier between rows of the wells defined in the microplate.

Abstract: A fluorescent microarray analyzer includes a light source for emitting a light beam, a light processing unit for focusing the light beam on the biochip and exciting fluorescent targets on the biochip to produce fluorescence, a focusing lens for focusing the fluorescence on a spectrophotometer, a spectrophotometer for detecting signal of the fluorescence, and an output device for selectively outputting/displaying the signal detected by the spectrophotometer. The resulting signal of the output device does not need to be converted into image data for analysis. For acquiring a more accurate result of detection of signal of fluorescence from the fluorescent targets, the photomultiplier tube of the conventional biochip scanner device is replaced with the spectrophotometer of fluorescent microarray analyzer of the present invention and the filter is removed.

Abstract: A biochip scanner device includes a light source for emitting a light beam; a light processing unit for focusing the light beam onto the biochip to excite fluorescence from a sample spot on the biochip; a filter for filtering off the light beam from the light source and the scattered light from the surface on the biochip; a photomultiplier tube (PMT) for detecting and converting the fluorescence into a current signal; and an output device for outputting/displaying the current signal detected by the PMT. The output device controls the platform to match the pattern of the biochip. No conversion of the output signal of the output device into image data is needed. A real-time analysis proceeds while samples are being scanned on the biochip. The biochip scanner device of the present invention reads the current signal from PMT directly without processing it into image data and setting lens before the PMT is no longer needed.

Abstract: A fluorescent microarray analyzer includes a light source for emitting a light beam, a light processing unit for focusing the light beam on the biochip and exciting fluorescent targets on the biochip to produce fluorescence, a focusing lens for focusing the fluorescence on a spectrophotometer, a spectrophotometer for detecting signal of the fluorescence, and an output device for selectively outputting/displaying the signal detected by the spectrophotometer. The resulting signal of the output device does not need to be converted into image data for analysis. For acquiring a more accurate result of detection of signal of fluorescence from the fluorescent targets, the photomultiplier tube of the conventional biochip scanner device is replaced with the spectrophotometer of fluorescent microarray analyzer of the present invention and the filter is removed.

Abstract: A CCD-based biochip reader includes a light source for emitting light beams, a collimating lens for converting the light beams into wide parallel rays of light, passing said wide parallel rays of light through a biochip and exciting fluorescence from fluorescent targets on the biochip, a focusing lens for focusing the fluorescence, a filter for filtering out said parallel rays of light, and a charge-coupled device camera for generating images from said fluorescence. For recording intensity of the fluorescence from the fluorescent targets, images of the charge-coupled device camera is converted into digital data through an image converting device. Wide parallel laser beams are produced by the laser and through the collimating lens, and excite all samples on the biochip with high efficiency at the same time. In addition, time for analysis is saved when fluorescent images of a large area on biochips are collected and analyzed through the charge-coupled device camera.

Abstract: A biochip scanner device includes a light source for emitting a light beam; a light processing unit for focusing the light beam onto the biochip to excite fluorescence from a fluorescent target on the biochip; a filter for filtering off the light beam from the light source; a photomultiplier tube (PMT) for detecting and converting the fluorescence into an electrical signal; and an output device for outputting/displaying the electrical signal detected by the PMT. No conversion of the output signal of the output device into image data is needed. A real-time analysis proceeds while samples are being scanned on the biochip. The biochip scanner device of the present invention reads the electrical signal from PMT directly without processing it into image data and setting lens before the PMT is no longer needed. As a result, the structure of the device is simplified and the cost for production is reduced.