Abstract: Provided herein is an antifolate predictive response signature for use in determining the response of a subject suffering from cancer to antifolate therapy. Also provided are methods and compositions for determining proliferation in a sample obtained from a subject suffering from cancer through the use of a proliferation gene signature as well as methods for predicting response of a subject suffering from cancer based on an assessment of proliferation in a sample obtained from the subject.

Abstract: A SAR ADC may include a plurality of capacitor networks, wherein each capacitor network of the a plurality of capacitor networks has a plurality of sampling capacitors for sampling over a plurality of sampling sub-phases an analog input signal to the SAR ADC and at least one non-sampling capacitor. The SAR ADC may also include a DAC comprising a plurality of sub-DACs including at least a first sub-DAC representing most significant bits of an output of the SAR ADC, wherein the output of the first sub-DAC is coupled to the sampling capacitors of the plurality of capacitor networks and a second sub-DAC representing bits of the output of the SAR ADC lesser in magnitude significance than those of the first sub-DAC, wherein the output of the second sub-DAC is coupled to a respective one of at least one non-sampling capacitor of each of the plurality of capacitor networks.

Abstract: A cooking device, which includes: a frame; a base, connected to the frame; a pot assembly, including a pot, the pot being configured to be connected to the base; a first seasoning mechanism, disposed on the frame, the first seasoning mechanism being capable of conveying solid materials into the pot; and a second seasoning mechanism, disposed on the frame, the second seasoning mechanism being capable of conveying liquid materials into the pot. During a cooking process, the cooking device may respectively put the solid materials and the liquid materials into the pot by using the first seasoning mechanism and the second seasoning mechanism, so as to replace manual material feeding. Therefore, the problems in the related art of long cooking time during the using of an automatic cooking machine by a user and poor user experience are solved, thereby improving user experience.

Abstract: The present disclosure generally relates to a composition matter and a method for cancer treatment. In particular, a composition matter as an antitumor immunotherapy comprising a polyethyleneimine derivative as an immunoadjuvant, a chemotherapeutic drug, and optional components such as a microRNA, messenger RNA, plasmid DNA, siRNA, oligonucleotide, or a cyclic dinucleotide. A method for treating a subject with a cancer by administrating a therapeutic effective amount of a composition comprising a polyethyleneimine derivative and an antitumor agent to the subject in need of relief from said cancer is also within the scope of this disclosure.

Abstract: The present disclosure provides an apparatus and method for producing a policosanol having a specific chromatographic fingerprint. The apparatus of the present disclosure has a feed tank and receiving tanks which are connected to a vacuum system. The method of the present disclosure is carried out by a high vacuum rectification process and includes: firstly, feeding a saponified crude alkanol into a melting tank in which the material is melted and then flows into the feed tank, and then injecting the material into a rectifying still using a delivery pump, followed by first rectification under vacuum condition and sequential collection of fractions at different phases from the tower top and stillage residue from the tower bottom; and after the completion of the rectification of the first batch crude product, carrying out second feeding on the basis of consistent vacuum in the feed tank and the rectifying tower.

Abstract: One or more machine readable storage media, an apparatus, and a method. The apparatus provides a mechanism to implement a trusted telemetry governor (TTG) inside a trusted execution environment. The TTG is to determine a security policy to be applied to telemetry data corresponding to component of a computing infrastructure, receive the telemetry data in encrypted format and, based on the security policy: process the telemetry data including at least one of generating transformed telemetry data or analyzing the telemetry data to generate a report therefrom, and generating telemetry information from the telemetry data. The telemetry information includes at least one of processed telemetry data, a report, or a recommendation based on an analysis of the telemetry data. The TTG is to send the telemetry information outside of the trusted execution environment to a consumer of the telemetry data.

Abstract: A multi-piston-dedicated heat dissipating caliper cover with easy installation includes a caliper cover body, a fixing assembly and at least two first fixing bolts. One side edge of the caliper cover body extends toward a side to form a first arc-shaped side plate, and the other side edge of the caliper cover body extends toward a side to form a second arc-shaped side plate. The fixing assembly includes a bolt fixing sheet and a positioning sheet, one end of the positioning sheet is connected with the bolt fixing sheet through a second fixing bolt, and the other end of the positioning sheet passes through a strip-shaped hole and then is inserted into a slot at a top of a brake caliper. By disposing the heat dissipating silicone sheet, a contact area is increased, which allows the heat generated by the brake caliper to be quickly transferred to the caliper cover.

Abstract: Methods and systems for reducing solar cell degradation are provided. The methods and systems related to frequently applying large reverse bias current-voltage (J-V) sweeps to the cell to reduce the rates of internal degradation of the solar cells. The frequent sweeps serve to detrap charge carriers formed in the cell due to photo-oxidative damage. This detrapping reduces the rate of power conversion efficiency (PCE) degradation throughout the life of the solar cell.

Abstract: An output control circuit, a start power supply, and a battery clip are provided in the present disclosure. The output control circuit includes a power supply end, a load end, and a first protection module. The power supply end is configured to be connected with a power supply module. The load end is configured to be connected with an external load device. The power supply end is electrically connected with the load end at least through the first protection module, to implement the power supply module supplying power to the external load device at least through the first protection module. The first protection module is configured to monitor a power supply state of the power supply module supplying power to the external load device, and disconnect a connection between the power supply end and the load end or limit a current based on the power supply state.

Abstract: The present application relates to the technical field of welding materials, and particularly to a lead-free and halogen-free solder paste, including a solder alloy powder and a welding flux with a mass ratio of 85-90:10-15, the solder alloy powder is Sn-2.5Be-0.8Ag-0.5Cu alloy powder, and the welding flux includes the following components: itaconic acid, succinic acid, a surfactant, a thixotropic agent, modified rosin, a composite solvent, a corrosion inhibitor, and an acrylic type activator. Its preparation method includes the following steps: mixing the modified rosin, the composite solvent and the corrosion inhibitor, heating under stirring, cooling, adding itaconic acid, succinic acid and the acrylic type activator under stirring, cooling, adding the thixotropic agent for emulsification dispersion, adding the surfactant under stirring, grinding to obtain a welding flux after cooling, and stirring the solder alloy powder and the welding flux under vacuum to obtain the solder paste.

Abstract: The present invention provides novel compounds having the general formula (I) wherein R1 to R6, and m are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The present disclosure discloses a high-pressure white-red-green-blue (WRGB) string light, including a controller and a string light main body. The controller is connected with the string light main body; the string light main body is provided with a plurality of WRGB bulbs; the controller includes a first power supply module and a main control module; the first power supply module is adapted to be connected to a mains supply to supply power to the main control module; the WRGB bulbs include a second power supply module, an auxiliary control module and a lighting module; the second power supply module is adapted to be connected to the controller or the main supply to supply power to the auxiliary control module and the lighting module; and the main control module is adapted to send a control signal to the auxiliary control module.

Abstract: According to an embodiment, an apparatus for a plasma processing system is provided. The apparatus includes a conductive conical frustum having an open top base, an open bottom base, and a surface area coupling the open top base to the open bottom base. A conductive cylinder is positioned within the conductive conical frustum with a closed bottom base and an open top base. The open top base of the conductive cylinder is connected to sidewalls of the open top base of the conductive conical frustum. The conductive cylinder has a height shorter than the height of the conductive conical frustum. The apparatus is configured to provide a broadband RF transition from a matching network to a resonating structure of the plasma processing system for frequencies ranging between 13 megahertz (MHz) and 220 MHz.

Abstract: A method and a system for determining a supporting structure by combining a stress environment and an underground surrounding rock structure are provided in the disclosure, which relates to the technical field of stability analysis of coal-mine rock mass. The method includes: defining a stress peak position and an in-situ stress position by determining the stress environment; identifying the underground surrounding rock structure, identifying lithology and constructing a three-dimensional model of a rock stratum to analyze damage degree of the rock stratum; pretreating, namely normalizing, the damage degree of the rock stratum at two sides and comparing the damage degree of the rock stratum at a roof and the floor; and identifying the supporting structure and determining supporting effectiveness and a supporting length. The method of the disclosure is different from related art, and ensures that the supporting structure meets mechanical foundation and practical engineering requirements as a whole.

Abstract: The present disclosure provides a method and an apparatus for identifying a dark web website in a scenario where a plurality of pages are accessed simultaneously. The method includes: obtaining browsed network traffic packets of websites to be identified, and extracting direction sequence features from the network traffic packets; dividing the direction sequence features into a plurality of subsequence features based on a plurality of sliding windows, and inputting the plurality of subsequence features into a neural network model to extract preset pattern features; analyzing a correlation of the preset pattern features using a target website identification model to obtain a probability result of a target website being accessed; obtaining a target website identification result in the website to be identified based on the probability results and a preset classification model.

Abstract: Embodiments relate to a continuous process for the production of hydroxyethylpiperazine that includes feeding neat piperazine, recycled piperazine, and ethylene oxide to a reactor to form crude hydroxyethylpiperazine, in which the reactor is a continuous stirred tank reactor or a plug flow reactor. The process further includes continuously feeding the crude hydroxyethylpiperazine from the reactor to a distillation system that includes at least one distillation column, the distillation system produces at least a recycled piperazine stream and a hydroxyethylpiperazine stream, the recycled piperazine stream includes the recycled piperazine that is fed to the reactor to form the crude hydroxyethylpiperazine, and the hydroxyethylpiperazine stream includes at least 60 wt % of hydroxyethylpiperazine based on a total weight of the hydroxyethylpiperazine stream.

Abstract: The present disclosure provides a supporting base, a superconducting magnet assembly, and a method for manufacturing the supporting base. The supporting base comprises an annular supporting base body and a reinforcing hoop, the axes of the supporting base body and reinforcing hoop are both arranged coaxially with the axis of the inner coil, and the reinforcing hoop is sleeved and fixed on an outer surface of the supporting base body, wherein first connecting parts are provided on the reinforcing hoop, and bracket units for supporting a shield coil of a superconducting magnet can be connected to the reinforcing hoop using the first connecting parts. By means of providing the reinforcing hoop, the rigidity of the whole inner coil is increased, the thickness of the supporting base body is decreased, and material costs are reduced; the reinforcing hoop provides a connection interface for the bracket units, and the bracket units can be directly connected to the reinforcing hoop, further reducing material costs.

Abstract: The present invention relates to a genetically modified plant which has enhanced resistance to one or more fungal pathogen(s).

Abstract: A new and distinct cultivar of Echinacea plant named ‘Balscrasux’, characterized by its double-type, medium red-orange and purplish-red colored inflorescences, dark green-colored foliage, and moderately vigorous, semi-upright growth habit, is disclosed.