Abstract: The Ultraviolet pretreatment device in the present invention relates to an interface technique in the field of coupling technology for the analysis of chemical element species. The objective is to provide an Ultraviolet pretreatment device with simple structure, enhanced UV illuminance, and high digestion efficiency. The Ultraviolet pretreatment device in the present invention comprises a low pressure Mercury lamp and a quartz tube, wherein, the low pressure Mercury lamp comprises a lamp tube, electrodes and a power source. The quartz tube is located within the lamp tube, the two ends of the quartz tube are fixedly and respectively joined with the tube wall of the lamp tube, the inner wall of the lamp tube and the outer wall of the quartz tube form a sealed gas chamber, and the electrodes are located in the gas chamber.

Abstract: Sodium butyrate was chronically administrated through diet supplementation at 5% w/w in a high fat diet. Supplementation of butyrate prevented development of insulin resistance and obesity in C57BL/6J mice on a high fat diet, and in mice fed on a regular diet of tributyrin. Fasting blood glucose, insulin, and insulin tolerance were all reserved in the butyrate-treated mice. The body fat content was maintained at 10% without a reduction in food intake. Adaptive thermogenesis and fatty acid oxidation were enhanced. An increase in mitochondria function and biogenesis was observed in the skeletal muscle and brown fat, and Type 1 muscle fiber was enriched in the skeletal muscle. In genetically obese mice, supplementation of butyrate led to an increase in insulin sensitivity and reduction in adiposity. Dietary supplementation of butyrate can prevent and treat diet-induced insulin resistance.

Abstract: Sodium butyrate was chronically administrated through diet supplementation at 5% w/w in a high fat diet. Supplementation of butyrate prevented development of insulin resistance and obesity in C57BL/6J mice on a high fat diet, and in mice fed on a regular diet of tributyrin. Fasting blood glucose, insulin, and insulin tolerance were all reserved in the butyrate-treated mice. The body fat content was maintained at 10% without a reduction in food intake. Adaptive thermogenesis and fatty acid oxidation were enhanced. An increase in mitochondria function and biogenesis was observed in the skeletal muscle and brown fat, and Type 1 muscle fiber was enriched in the skeletal muscle. In genetically obese mice, supplementation of butyrate led to an increase in insulin sensitivity and reduction in adiposity. Dietary supplementation of butyrate can prevent and treat diet-induced insulin resistance.