Abstract: A preprocessing system includes a first port, where one end of the first port is coupled to a first switch, and the other end of the first port is suspended, where the first switch has a connecting end configured to couple to a first interface and is configured to connect a filter and the first interface, a second port configured to receive a first signal or a second signal, where the filter is configured to filter the first signal to obtain a first positioning signal and a second positioning signal, provide the first positioning signal for the first switch, and provide the second positioning signal for a second interface of a global navigation satellite system (GNSS) chip to adapt to a plurality of antenna configuration types and to achieve universality.

Abstract: Provided is a GII.4 norovirus virus-like particle or active fragment thereof, and use thereof, the virus-like particle comprising or being composed of an amino acid sequence shown as SEQ ID NO: 4. Further, provided is a composition or a kit comprising the GII.4 norovirus virus-like particle, and use thereof. The objective of covering multiple genotypes is achieved by using a single antigen of the invention, the process difficulty of the preparation for a pharmaceutical composition or a vaccine can be reduced, and the production cost is decreased. Also, provided is a norovirus immune composition or a kit comprising GII.2, GII.4, GII.6, and GII.17 norovirus virus-like particles or active fragments thereof, and use thereof.

Abstract: A method for calibrating a driving risk identification model includes: S1. establishing a vehicle platform by installing an information acquisition device on a test vehicle; S2. acquiring synchronized test data related to the test vehicle and driving scenarios; S3. extracting moments when the drivers start to press the accelerator pedal, start to release the accelerator pedal, start to press the brake pedal in the driving scenarios, and start to release the brake pedal, so as to define risk level values respectively corresponding to the moments; S4. obtaining a risk identification curve of the drivers in different driving scenarios, wherein the risk identification curve represents the drivers' judgment of the risk level over time; S5. using the risk identification curve to calibrate the driving risk identification model.

Abstract: A droplet delivery device includes an ejector plate having an overall area that includes an outer area that is solid without holes and inner, active area with holes.

Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

Abstract: A pharmaceutical composition comprising: i) a herpes gE protein, an active fragment of the protein, a variant of the protein, or a mixture of at least two of them; ii) an immunostimulatory composition comprising a saponin and a CpG oligodeoxynucleotide, or consisting of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide. Use of the pharmaceutical composition in the preparation of a medicament for preventing and/or treating a varicella-zoster virus infection and/or a varicella-zoster virus mediated disease. The pharmaceutical composition achieves an unexpected technical effect and can mediate a stronger immune response.

Abstract: The present invention belongs to the field of biopharmaceutics and in particular relates to a pharmaceutical composition. The pharmaceutical composition comprises a hepatitis B surface antigen, a hepatitis B core antigen, and an immunostimulatory composition, wherein the immunostimulatory composition comprises a saponin and a CpG oligodeoxynucleotide, or consists of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide.

Abstract: Provided is an immunostimulatory composition, comprising a saponin and a CpG oligodeoxynucleotide, or consisting of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide, wherein the sequence of the CpG oligodeoxynucleotide has two or more copies of 5?-TTCGTT-3? motif or 5?-TCGTCGTCG-3? motif. Also provided is use of the immunostimulatory composition in the preparation of a medication for treating diseases.

Abstract: A droplet delivery device includes a housing with a mouthpiece port or outlet from a nasal device for releasing fluid droplets, a fluid reservoir, and an ejector bracket having a membrane positioned between a mesh with a plurality of openings and a vibrating member that is coupled to an electronic transducer, such as an ultrasonic transducer. The transducer vibrates the vibrating member which causes the membrane to push fluid supplied by the reservoir through the mesh to generate droplets in an ejected stream released through the outlet.

Abstract: The present invention discloses a medical prediction method and system based on a semantic graph network, which recognizes an entity in an electronic medical record based on domain knowledge, and uses a two-way gated loop unit to learn a sequence features of a text. Secondly, in order to extract a semantic relation in the electronic medical record in a fine-granularity manner, the present invention defines two types of subgraphs, graph representation based on defined knowledge and graph representation based on undefined knowledge, and uses a Graph Convolution Network (GCN) and a Graph Attention Network (GAT) to extract a semantic relation representation, where the graph representation based on undefined knowledge allows the learning of a relation between an entity or an word and the graph representation based on undefined knowledge, and it also allows to learn a relation between word or entity and itself, in order to translate entity or word representation into a uniform graph embedding representation.

Abstract: The present provides a visual positioning method and system based on a Gaussian process and a storage medium. The method includes: collecting image of surrounding environment and moving trajectory points while traveling (S100); extracting global features and semantic features from images (S200); processing the extracted global features and semantic features and the moving trajectory points according to a preset processing rule to obtain a Gaussian process observation model (S300); and reconstructing a Bayes filtering framework according to the Gaussian process observation model, endowing a current trajectory with an initial position point, and generating a next position point of the current trajectory, the next position point being used for providing a positioning guidance for navigation (S400). An association between a current state and a historical state can be established, so that the accuracy of a predicted next position point is improved, and accurate navigation can be provided for a robot motion.

Abstract: The present invention discloses a pharmaceutical preparation for treating hepatitis B, a preparation method and use thereof. The pharmaceutical preparation comprises a solution of hepatitis B surface antigen, further a solution of hepatitis B core antigen, and furthermore an oligodeoxynucleotide solution. The pharmaceutical preparation is free of saccharide, has a simple composition and a good antigen stability, without the adverse reactions caused by aluminum adjuvants, and shows good preservation effects in long-term stability experiments.

Abstract: The present application provides a low carbon martensitic high temperature strength steel and a preparation method thereof, wherein the chemical composition of the low carbon martensitic high temperature strength steel are: C: 0.10-0.25 wt %, Cr: 10.0-13.0 wt %, Ni: 2.0-3.2 wt %, Mo: 1.50-2.50 wt %, Si?0.60 wt %, Mn?0.60 wt %, W: 0.4-0.8 wt %, V: 0.1-0.5 wt %, Co: 0.3-0.6 wt %, Al: 0.3-1.0 wt %, Nb: 0.01-0.2 wt %, and a balance of Fe. The high temperature strength steel of the present application achieves high strength at high temperature by simultaneously precipitating both nano-coherent carbides and intermetallic compounds. It has an excellent toughness, and can be used for certain structural parts under special working conditions, such as aero-engines to increase its service life and service temperature.

Abstract: The present application provides a hot-work die steel and a preparation method thereof, wherein the chemical constituents of the hot-work die steel in mass percentage are as follows: C: 0.20-0.32 wt %, Si: ?0.5 wt %, Mn: ?0.5 wt %, Cr: 1.5-2.8 wt %, Mo: 1.5-2.5 wt %, W: 0.5-1.2 wt %, Ni: 0.5-1.6 wt %, V: 0.15-0.7 wt %, Nb: 0.01-0.1 wt %, and a balance of iron, wherein an alloying degree is 5-7%; a tensile strength of the hot-work die steel at 700° C. is 560-700 MPa; a value of hardness of the hot-work die steel at room temperature is 32-38 HRC after holding at 700° C. for 3-5 h; and the hot-work die steel has an elongation of 14% to 16% at room temperature, a percentage reduction of area of 48% to 65%, and an impact toughness of 52-63 J at room temperature. The hot-work die steel of the present application has an excellent thermal stability as well as a good plasticity and a toughness at room temperature.

Abstract: An application security authentication method, including: step 202, acquiring an application file to be downloaded and extracting signature information from the application file; step 204, acquiring public key information contained in a multilevel key hierarchy, and acquiring public key information of the currently highest priority according to a priority order of the public key information; step 206, authenticating the signature information with the acquired public key information of the currently highest priority; and step 208, allowing the application file to be downloaded if an authentication of the signature information is passed.

Abstract: The present application provides a hot-work die steel and a preparation method thereof wherein the chemical constituents of the hot-work die steel in mass percentage are as follows: C: 0.20-0.32 wt %, Si: ?0.5 wt %, Mn: ?0.5 wt %, Cr: 1.5-2.8 wt %, Mo: 1.5-2.5 wt %, W: 0.5-1.2 wt %, Ni: 0.5-1.6 wt %, V: 0.15-0.7 wt %, Nb: 0.01-0.1 wt %, and a balance of iron, wherein an alloying degree is 5-7%; a tensile strength of the hot-work die steel at 700° C. is 560-700 MPa; a value of hardness of the hot-work die steel at room temperature is 32-38 HRC after holding at 700° C. for 3-5 h; and the hot-work die steel has an elongation of 14% to 16% at room temperature, a percentage reduction of area of 48% to 65%, and an impact toughness of 52-63 J at room temperature. The hot-work die steel of the present application has an excellent thermal stability as well as a good plasticity and a toughness at room temperature.

Abstract: A method for producing ?? T cells modified by a chimeric antigen receptor, comprising: transfecting K562 cells with shFPPS targeted to FPP synthase by means of a lentiviral vector, such that the expression of FPPS in the K562 cells is lowered and a K562-shFPPS cell line with reduced FPPS expression is constructed; adding the K562-shFPPS cell line into a ?? T cell culture system for co-culturing with the ?? T cells, wherein it is found that the K562-shFPPS cell line can facilitate in vitro differentiation and proliferation of the ?? T cells; and adding a CAR-expressing lentiviral vector to the ?? T cell culture system comprising the cell line for co-culturing, wherein it is found that the K562-shFPPS cell line can further effectively improve the transfection rate of CAR genes. The provided solution effectively overcomes the technical challenge of the large-scale production of CAR-?? T cells, and has a good application prospect.

Abstract: The invention provides a file storage method, a file search method and a file storage system based on public-key encryption with keyword search. The method comprises: receiving a user file storage request sent from a data possessor, acquiring access control attribute information for access to a user file, security level parameters and a keyword set of the user file, generating a file attribute vector of the user file by means of the access control attribute information and the keyword set, acquiring a public-secret key pair used for encrypting the file attribute vector from a pre-generated key space, encrypting the file attribute vector by means of a public key in the public-secret key pair to obtain a ciphertext corresponding to the file attribute vector, and transmitting the ciphertext corresponding to the file attribute vector and a ciphertext of the user file to a preset storage server.

Abstract: A method for accessing payment terminal, including: acquiring page access information through a browser; loading a corresponding page according to the page access information and generating an access control object; receiving an operation selected on the page; calling the access control object according to the operation; and accessing a connected payment terminal through the access control object, and controlling the payment terminal to perform the operation.

Abstract: A method for upgrading POS terminal software, including: starting a POS terminal; detecting whether the POS terminal is connected to a mobile storage device; detecting whether there is a valid software upgrade package file in the mobile storage device if the POS terminal is connected to the mobile storage device; displaying a software upgrade management interface including a name of the valid software upgrade package file on the POS terminal if there is a valid software upgrade package file in the mobile storage device; obtaining a software upgrade package file selected through the software upgrade management interface; performing an upgrade according to the selected software upgrade package file; and restarting the POS terminal if the upgrade is successful.