Abstract: Disclosed are a series of compounds with a nitrogen-containing spiro structure and an application thereof in the preparation of an RET kinase inhibitor. Specifically, disclosed is a compound as shown in formula (II) or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed are a non-fluorinated quinolone compound and use thereof, specifically relating to a compound represented by formula (II) and a pharmaceutically acceptable salt thereof.

Abstract: A method and apparatus for session management in a wireless network are disclosed. For example, a user endpoint (UE) device, sends a request for a session internet protocol (IP) address assignment using an interface IP address, configures the UE device with the session IP address, provides to a controller an association of the interface and session IP addresses, and receives packets addressed to the session IP address via an access network entity associated with the interface IP address. In one example, a controller receives an association of an interface IP address with a session IP address from an attached UE device, provides to a network node an update on a route to reach the session IP address through the interface IP address, identifies an active interface IP address to receive packets, and configures an open flow switch or router for routing the packets towards the active interface IP address.

Abstract: Facilitating device contexts, operational modes, and policy driven enhancements for paging in advanced networks (e.g., 4G, 5G, 6G, and beyond) is provided herein. Operations of a network device can comprise analyzing a group of contextual data for a user equipment device, and mobility management behaviors historically implemented for the user equipment device and based on an indication that a page request is scheduled to be sent to the user equipment device. The operations can also comprise configuring a paging message for the user equipment device based on the contextual data and the mobility management behaviors. Further, the operations can comprise sending the paging message to the user equipment device.

Abstract: Disclosed herein are systems and method for providing quality of service to data streams transmitted via a single protocol stream. A scheduler of a sender can receive profiles corresponding to streams of data generated by an application of the sender. The scheduler can receive, from a receiver receiving the streams of data, congestion information of some the streams of data. The scheduler can determine, according to the congestion information and the profiles, a priority of a first stream with respect to a second stream of the streams of data, for a single protocol stream. An assembler of the sender can generate a plurality of packets of the single protocol stream using first packets of the first stream and second packets of the second stream in accordance with the priority. The sender can transmit to the receiver, the single protocol stream comprising the plurality of packets.

Abstract: The described technology is generally directed towards a frequency-aware cellular communication network. A mobile device, or a radio access network (RAN) device at a base station in communication with the mobile device, can proactively notify a core network device regarding changes of a frequency band used for communications between the mobile device and the base station. The core network can use received notifications to adjust service provided to the mobile device.

Abstract: Connecting user equipment (UE) to an application can be managed based on UE movement and location. During data session between UE and application, a communication management component (CMC) associated with anchor network component (ANC) or serving network component (SNC) determines UE location, and connects UE to the ANC and SNC, which enables access of the application via a data network associated with ANC. As UE moves, CMC tracks UE movement and communication conditions. If, when UE is at second location, a communication condition breaches threshold level, CMC determines whether interruption of the data session is permitted. If not, CMC determines whether there is a local SNC in proximity to second location. If there is, CMC can switch UE from SNC to local SNC, which can access local application content via local data network associated with application. If interruption permitted, UE deactivates and reactivates to connect to local ANC.

Abstract: The present invention relates to the technical field of drug synthesis. Disclosed are a crystal form of a macrocyclic compound, and a preparation method therefor and the use thereof. The macrocyclic compound is (6R,16R)-9-fluoro-16-methyl-13-oxa-2,17,21,25-tetraazapentane [16.6.2.02,6.07,12.022,26]dihexadecane-1(25),7,9,11,18(26),19,21,23-octane-19-carbonitrile. The X-ray diffraction pattern of the crystal form has characteristic peaks at 2? values of 9.49±0.2, 10.60±0.2, 11.54±0.2, 14.10±0.2, 17.09±0.2, 19.15±0.2, 20.30±0.2, 22.85±0.2, 23.89±0.2 and 27.74±0.2. The crystal form is hygroscopicity-free, has a good stability and pharmacokinetic properties.

Abstract: Systems, methods, and apparatuses for transmitting, by a wireless communication device, to an access management function (AMF) of a core network, a request for a session to be established with a wireless communication node, the session requested to include a dedicated internet protocol (IP) flow for a low queuing latency, low loss, and scalable throughput (L4S) protocol, and receiving, by the wireless communication device, via the AMF from a session management function (SMF) of the core network, a response to the request, the response indicating that the L4S protocol is supported by the wireless communication node.

Abstract: Systems, methods, and apparatuses for transmitting, by a wireless communication device, to an access management function (AMF) of a core network, a request for a session to be established with a wireless communication node, the request indicating a low queuing latency, low loss, and scalable throughput (L4S) protocol is to be used for the session, and a registration area corresponding to the wireless communication node, and receiving, by the wireless communication device, via the AMF from a session management function (SMF) of the core network, a response to the request, the response indicating that the L4S protocol is supported by the wireless communication node according to the registration area.

Abstract: Systems, methods, and apparatuses for establishing, by a wireless communication device, a first connection with a first wireless communication node supporting a low queuing latency, low loss, and scalable throughput (L4S) protocol, the first connection including a dedicated internet protocol (IP) flow for the L4S protocol, switching, by the wireless communication device, from the first connection to a second connection with a second wireless communication node, and determining, by the wireless communication device, a support status of the L4S protocol by the second wireless communication node, according to the dedicated IP flow responsive to switching.

Abstract: A class of piperazine derivatives and application thereof, specifically compound represented by formula (III) or pharmaceutically acceptable salt thereof.

Abstract: Concepts and technologies are disclosed herein for creating and using native virtual probes in computing environments. A request for a service that includes a virtual function can be received, where the virtual function is to be monitored by a native virtual probe. An image of the service can be obtained, where the image can include a first image component for the virtual function and a second image component for the native virtual probe. The image can be deployed. Deployment of the image can result in instantiation of the virtual function on a computing device and instantiation of the native virtual probe on the computing device.

Abstract: The described technology is generally directed towards a frequency-aware cellular communication network. A mobile device, or a radio access network (RAN) device at a base station in communication with the mobile device, can proactively notify a core network device regarding changes of a frequency band used for communications between the mobile device and the base station. The core network can use received notifications to adjust service provided to the mobile device.

Abstract: A method and apparatus for session management in a wireless network are disclosed. For example, a user endpoint (UE) device, sends a request for a session internet protocol (IP) address assignment using an interface IP address, configures the UE device with the session IP address, provides to a controller an association of the interface and session IP addresses, and receives packets addressed to the session IP address via an access network entity associated with the interface IP address. In one example, a controller receives an association of an interface IP address with a session IP address from an attached UE device, provides to a network node an update on a route to reach the session IP address through the interface IP address, identifies an active interface IP address to receive packets, and configures an open flow switch or router for routing the packets towards the active interface IP address.

Abstract: Connecting user equipment (UE) to an application can be managed based on UE movement and location. During data session between UE and application, a communication management component (CMC) associated with anchor network component (ANC) or serving network component (SNC) determines UE location, and connects UE to the ANC and SNC, which enables access of the application via a data network associated with ANC. As UE moves, CMC tracks UE movement and communication conditions. If, when UE is at second location, a communication condition breaches threshold level, CMC determines whether interruption of the data session is permitted. If not, CMC determines whether there is a local SNC in proximity to second location. If there is, CMC can switch UE from SNC to local SNC, which can access local application content via local data network associated with application. If interruption permitted, UE deactivates and reactivates to connect to local ANC.

Abstract: Facilitating device contexts, operational modes, and policy driven enhancements for paging in advanced networks (e.g., 4G, 5G, 6G, and beyond) is provided herein. Operations of a network device can comprise analyzing a group of contextual data for a user equipment device, and mobility management behaviors historically implemented for the user equipment device and based on an indication that a page request is scheduled to be sent to the user equipment device. The operations can also comprise configuring a paging message for the user equipment device based on the contextual data and the mobility management behaviors. Further, the operations can comprise sending the paging message to the user equipment device.

Abstract: Disclosed herein are related to devices and methods for communication. In one aspect, a device includes a first processor and a second processor. The first processor may be configured to generate a first set of packets associated with an application data unit in a first layer corresponding to content data. Each packet of the first set of packets may include a flag indicative of an association with the application data unit. The second processor may be configured to generate a second set of one or more packets in a second layer for transmission, in response to determining that the first set of packets is associated with the application data unit according to flags of the first set of packets. The second processor may be configured to schedule to transmit the second set of one or more packets in the second layer within a defined time period.

Abstract: Aspects of this technical solution can include identifying, by a wireless communication device, one or more of a plurality of data units corresponding to a set, the set configured according to a heuristic indicating a quality of service (QoS) level corresponding to the set. The wireless communication device can determine one or more metrics indicating respective states of the received plurality of data units. The wireless communication device can select according to the one or more metrics satisfying the heuristic, the set including the plurality of received data units corresponding to the set, from among a plurality of sets each having a corresponding QoS level. The wireless communication device can transmit, according to a set of one or more of the metrics satisfying the heuristic and according to the QoS level corresponding to the set, a set of one or more of the plurality of received data units corresponding to the one or more of the metrics.

Abstract: Disclosed herein are systems and methods for facilitating wireless communication of a wearable device. In one aspect, a wireless device receives a paging message from a cellular network, via a wireless link between the wireless device and a companion device. The paging message can be received while a cellular modem of the wireless device is operating in reduced power mode and not registered with the cellular network, and the companion device is registered with the cellular network. The wireless device can transition the cellular modem from the reduced power mode to an active mode in response to receiving the paging message via the wireless link with the companion device. The wireless device can register with the cellular network after the modem has transitioned to active mode, to establish a cellular link directly with the cellular network.