Abstract: An SGT MOSFET comprising a substrate, an epitaxial layer, a masking dielectric layer, an interlayer dielectric layer, a source lead-out contact hole, and a source conductive layer and a method for manufacturing the SGT MOSFET are provided. The epitaxial layer is on an upper surface of the substrate and comprises a cellular trench structure, a terminal lead-out structure, a source lead-out structure, a body region, and a source region. The source lead-out structure comprises a source lead-out conductive layer. The masking dielectric layer and the interlayer dielectric layer are sequentially stacked above the epitaxial layer. The source lead-out contact hole penetrates the interlayer dielectric layer and the masking dielectric layer and extends into the source lead-out conductive layer, The source conductive layer fills the source lead-out contact hole. The masking dielectric layer is formed between the interlayer dielectric layer and the epitaxial layer and masks the third dielectric layer.

Abstract: The present application relates to the technical filed of ablation needle, and provides a dual-mode tissue ablation needle including a needle body (1), an insulation assembly (2), and a water delivery assembly (3); the insulation assembly (2) is slidably sleeved outside the needle body (1); a water channel (121) is provided inside the insulation assembly (2), an end of the water channel (121) is in communication with the water delivery assembly (3), and an other end of the water channel (121) is in communication with outside. The present application is simple in structure, which is easy to operate and use, and the structure can be used for dual-mode switching for different lesions and tumors of different sizes, the difficulty and risk of surgery is reduced, and the practicability is strong.

Abstract: The present invention relates to concentricolide and its derivatives, a method for the preparation of the compound and its derivatives, a pharmaceutical composition containing concentricolide and its derivatives, and use of the compound and its derivatives for the treatment and prevention of infection caused by human immunodeficiency virus (HIV).

Abstract: The present invention relates to concentricolide and its derivatives, a method for the preparation of the compound and its derivatives, a pharmaceutical composition containing concentricolide and its derivatives, and use of the compound and its derivatives for the treatment and prevention of infection caused by human immunodeficiency virus (HIV).