Patents by Inventor Jianxian GONG

Jianxian GONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis method of cyclosporine derivatives
    Patent number: 11840582
    Abstract: The present disclosure relates to a method of synthesizing cyclosporine derivatives. The method includes: providing a precursor fluid of the cyclosporine derivative, an alkaline fluid and a ClCH2OCOCl solution; premixing the precursor fluid and the alkaline fluid to obtain a premixed solution; feeding the premixed solution into a first reaction chamber, reacting to prepare a first reaction liquid; feeding the first reaction liquid into a second reaction chamber, reacting the first reaction liquid with a CO2 fluid to prepare a second reaction liquid; and reacting the second reaction liquid with the ClCH2OCOCl solution.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: December 12, 2023
    Assignee: Peking University Shenzhen Graduate School
    Inventors: Zhen Yang, Qingzhou Zhang, Fengxia Li, Chongguo Jiang, Jianxian Gong, Jun Huang, Weibin Zhang
  • SYNTHESIS METHOD OF CYCLOSPORINE DERIVATIVES
    Publication number: 20220315626
    Abstract: The present disclosure relates to a method of synthesizing cyclosporine derivatives. The method includes: providing a precursor fluid of the cyclosporine derivative, an alkaline fluid and a ClCH2OCOCl solution; premixing the precursor fluid and the alkaline fluid to obtain a premixed solution; feeding the premixed solution into a first reaction chamber, reacting to prepare a first reaction liquid; feeding the first reaction liquid into a second reaction chamber, reacting the first reaction liquid with a CO2 fluid to prepare a second reaction liquid; and reacting the second reaction liquid with the ClCH2OCOCl solution.
    Type: Application
    Filed: July 12, 2021
    Publication date: October 6, 2022
    Inventors: Zhen YANG, Qingzhou ZHANG, Fengxia LI, Chongguo JIANG, Jianxian GONG, Jun HUANG, Weibin ZHANG