Patents by Inventor Jianxin Bao

Jianxin Bao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating hearing disorders
    Patent number: 10434097
    Abstract: Disclosed herein are pharmaceuticals, compositions, kits, and methods for treating or preventing a hearing disorder in a subject in need thereof, wherein the pharmaceuticals, compositions, kits, and methods comprise administering a therapeutically effective amount of tetrandrine (TET) or a salt thereof.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: October 8, 2019
    Assignee: GATEWAY BIOTECHNOLOGY, INC.
    Inventors: Jianxin Bao, Xiaojie Chen
  • COMBINATIONS AND METHODS FOR TREATING NON AGE-RELATED HEARING IMPAIRMENT IN A SUBJECT
    Publication number: 20160022699
    Abstract: The present invention generally relates to treating non age-related hearing impairments. More specifically, the present invention provides combinations and methods for treatment and prevention of non age-related hearing impairment in a subject.
    Type: Application
    Filed: October 5, 2015
    Publication date: January 28, 2016
    Inventors: Jianxin Bao, Richard Chole
  • METHODS AND COMPOSITIONS FOR TREATING NON AGE RELATED HEARING IMPAIRMENT IN A SUBJECT
    Publication number: 20070078177
    Abstract: The invention provides methods for treating non-age related hearing impairments, especially sensorineural and neural hearing loss, in a subject in need of such treatment.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 5, 2007
    Applicant: WASHINGTON UNIVERSITY IN ST. LOUIS
    Inventor: Jianxin Bao
  • Neuregulin protein regulation of synaptic proteins
    Publication number: 20070042433
    Abstract: Methods are provided for discovery of new lead pharmaceuticals useful for addressing diseases and other problems of hearing. Compounds that modulate PSD-95 induction are discovered via use of the Nrg-1/Eos signaling pathway. Cell based assay systems are particularly described that identify modulation of binding of Nrg-ICD with an Eos binding site. Other features include the promotion and/or inhibition of Nrg-ICD translocation across nuclear membranes.
    Type: Application
    Filed: March 26, 2004
    Publication date: February 22, 2007
    Inventor: Jianxin Bao
  • A-form of cytoplasmic domain of nARIA (CRD-neuregulin) and uses thereof
    Patent number: 6933122
    Abstract: This invention provides nARIA-based assays for defining whether a subject has or is predisposed to developing a neoplastic disease. This invention further provides a nARIA-based method for maintaining synaptic connections between a neuron and a target cell.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: August 23, 2005
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Lorna W. Role, David Talmage, Jianxin Bao