Abstract: An AKR1C3 detection method, and a diagnostic kit for detecting AKR1C3 and use thereof. The AKR1C3 detection method includes the following steps: treating a formalin-fixed paraffin-embedded human tissue specimen sequentially using an organic solvent, an alcohol, and water; performing antigen retrieval on the treated formalin-fixed paraffin-embedded human tissue specimen in the presence of an antigen retrieval solution; co-incubating the antigen-retrieved formalin-fixed paraffin-embedded human tissue specimen with a blocking buffer to block a non-specific antigen; mixing the blocked formalin-fixed paraffin-embedded human tissue specimen with a certain concentration of AKR1C3 monoclonal antibody solution for primary antibody incubation, and mixing the primary antibody-incubated formalin-fixed paraffin-embedded human tissue specimen with a certain concentration of a secondary antibody solution for secondary antibody incubation.

Abstract: Described is a deuterated compound, and preparation method and use thereof The deuterated compound I has a structure as shown in Formula (I), wherein A is H or D, and at least one of eight As is D; M is H or an alkali metal, an alkaline earth metal, or an ammonium radical. The present invention provides use of the deuterated compound I as an internal standard for measuring the content of a metabolite II in a biological sample, wherein the metabolite II has a structure as shown in a Formula (II); wherein A is H; M is H or an alkali metal, an alkaline earth metal, or an ammonium radical. The present invention uses the deuterated compound I as an internal standard to quantitatively analysis the content of metabolite II at lower content in biological samples, which can not only meet the requirements for the lower limit of quantitation, but also meet the requirements for DMPK studies in clinical trials.

Abstract: Embodiments of the present application provide a navigation method, device and system. The method is applicable to a server and comprises: receiving current position characteristic information sent by a mobile terminal, and determining a position of an area matching the current position characteristic information based on the current position characteristic information and a locally stored database, and taking the determined position as an initial position; receiving target position characteristic information sent by the mobile terminal, determining a position of an area matching the target position characteristic information based on the target position characteristic information and the database, and taking the determined position as a target position; and determining a first route from the initial position to the target position and displaying the first route on an electronic map of the mobile terminal.

Abstract: The embodiments of the present application provide a navigation method, device and system. The method is applied to a server. The method includes: receiving current position feature information sent by a mobile terminal, determining a position of an area matching the current position feature information based on the current position feature information and a database stored in the server, and taking the position as an initial position; determining a position of one empty area of the areas as a target position based on position information corresponding to respective areas and correspondence relationship between identification information of the respective areas and the respective feature information currently stored in the database; and determining a first route from the initial position to the target position and displaying the first route on an electronic map of the mobile terminal.

Abstract: Embodiments of the present application provide a navigation method, device and system. The method is applicable to a server and comprises: receiving current position characteristic information sent by a mobile terminal, and determining a position of an area matching the current position characteristic information based on the current position characteristic information and a locally stored database, and taking the determined position as an initial position; receiving target position characteristic information sent by the mobile terminal, determining a position of an area matching the target position characteristic information based on the target position characteristic information and the database, and taking the determined position as a target position; and determining a first route from the initial position to the target position and displaying the first route on an electronic map of the mobile terminal.

Abstract: The embodiments of the present application provide a navigation method, device and system. The method is applied to a server. The method includes: receiving current position feature information sent by a mobile terminal, determining a position of an area matching the current position feature information based on the current position feature information and a database stored in the server, and taking the position as an initial position; determining a position of one empty area of the areas as a target position based on position information corresponding to respective areas and correspondence relationship between identification information of the respective areas and the respective feature information currently stored in the database; and determining a first route from the initial position to the target position and displaying the first route on an electronic map of the mobile terminal.