Patents by Inventor Jianxing Shao

Jianxing Shao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic urea derivatives useful in the treatment of cancer and other disorders
    Patent number: 8076488
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: December 13, 2011
    Assignee: Bayer Healthcare LLC
    Inventors: Jacques Dumas, Stephen Boyer, Sharad Verma, Lila Adnane, Yuanwei Chen, Wendy Lee, Barton Phillips, Roger A. Smith, William J. Scott, Jennifer Burke, Jianqing Chen, Zhi Chen, Jianmei Fan, Karl Miranda, Brian Raudenbush, Aniko Redman, Jianxing Shao, Ning Su, Gan Wang, Lin Yi, Qingming Zhu
  • RHO-KINASE INHIBITORS
    Publication number: 20100216789
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: January 15, 2010
    Publication date: August 26, 2010
    Inventors: Dhanapalan NAGARATHNAM, Uday Khire, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Chunguang Wang, Barry Hart, Olaf Weber, Mark Lynch, Lei Zhang, Lei Wang
  • RHO-KINASE INHIBITORS
    Publication number: 20100137324
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: February 2, 2010
    Publication date: June 3, 2010
    Inventors: Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • PROCESS FOR PREPARING QUINAZOLINE RHO-KINASE INHIBITORS AND INTERMEDIATES THEREOF
    Publication number: 20100125139
    Abstract: A process for the preparation of various quinazoline compounds which are useful as Rho-Kinase inhibitors, and thus having utility in the treatment of hypertension and other indications.
    Type: Application
    Filed: November 17, 2009
    Publication date: May 20, 2010
    Inventors: Donald BANKSTON, Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • Substituted thieno[3,2-D]pyrimidines as Rho kinase inhibitors
    Patent number: 7648986
    Abstract: Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: January 19, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Dhanapalan Nagarathnam, Uday Khire, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Chunguang Wang, Barry Hart, Olaf Weber, Mark Lynch, Lei Zhang, Lei Wang
  • Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
    Patent number: 7645878
    Abstract: A process for the preparation of various quinazoline compounds which are useful as Rho-Kinase inhibitors, and thus having utility in the treatment of hypertension and other indications.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: January 12, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Donald Bankston, Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • RHO-KINASE INHIBITORS
    Publication number: 20070238741
    Abstract: Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 11, 2007
    Inventors: Dhanapalan Nagarathnam, Uday Khire, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Chunguang Wang, Barry Hart, Olaf Weber, Mark Lynch, Lei Zhang, Lei Wang
  • Rho-kinase inhibitors
    Publication number: 20060142313
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: February 16, 2006
    Publication date: June 29, 2006
    Inventors: Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders
    Publication number: 20050038031
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Application
    Filed: March 1, 2004
    Publication date: February 17, 2005
    Inventors: Jacques Dumas, Stephen Boyer, Sharad Verma, Lila Adnane, Yuanwei Chen, Wendy Lee, Barton Phillips, Roger Smith, William Scott, Jennifer Burke, Jianqing Chen, Zhi Chen, Jianmei Fan, Karl Miranda, Brian Raudenbush, Aniko Redman, Jianxing Shao, Ning Su, Gan Wang, Lin Yi, Qingming Zhu
  • Pyrazole derivatives useful in the treatment of hyper-proliferative disorders
    Publication number: 20040180891
    Abstract: This invention relates to pyrazole derivatives of 1
    Type: Application
    Filed: March 15, 2004
    Publication date: September 16, 2004
    Inventors: Uday Khire, Chengzhi Zhang, Harold C E Kluender, Ingo Mugge, Zhengqui Hong, Jianxing Shao, Neil Bifulco, Pamela A Trail, Jacques Dumas, Rico C Lavoie, Xaio-Gao Liu, Veena Agarwal, Sharad K Verma, Lei Wang
  • Rho-kinase inhibitors
    Publication number: 20040014755
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: January 10, 2003
    Publication date: January 22, 2004
    Inventors: Dhanapalan Nagarathnam, Uday Khire, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Chunguang Wang, Barry Hart, Olaf Weber, Mark Lynch, Lei Zhang, Lei Wang
  • Process for preparing quinazoline Rho-kinase inhibitiors and intermediates thereof
    Publication number: 20030220357
    Abstract: A process for the preparation of various quinazoline compounds which are useful as Rho-Kinase inhibitors, and thus having utility in the treatment of hypertension and other indications.
    Type: Application
    Filed: September 24, 2002
    Publication date: November 27, 2003
    Inventors: Donald Bankston, Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch
  • Rho-kinase inhibitors
    Publication number: 20030125344
    Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
    Type: Application
    Filed: March 22, 2002
    Publication date: July 3, 2003
    Applicant: BAYER CORPORATION
    Inventors: Dhanaphalan Nagarathnam, Davoud Asgari, Jianxing Shao, Xiao-Gao Liu, Uday Khire, Chunguang Wang, Barry Hart, Stephen Boyer, Olaf Weber, Mark Lynch