Patents by Inventor Jianxun Lei

Jianxun Lei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CUBANYL BIGUANIDE COMPOUNDS
    Publication number: 20240067603
    Abstract: Biguanide compounds of formula where R1 comprises a cubanyl-substituted alkyl and R2 comprises a substituted or unsubstituted alkyl, and their use in the treatment of cancers and viral infections are described.
    Type: Application
    Filed: December 16, 2021
    Publication date: February 29, 2024
    Inventors: David A. POTTER, Zhijun GUO, Gunda GEORG, Kwon Ho HONG, Jianxun LEI, Elizabeth AMBROSE, Kris WHITE
  • Compositions and methods for treating pulmonary edema or lung inflammation
    Patent number: 11883528
    Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: January 30, 2024
    Assignee: Regents of the University of Minnesota
    Inventors: David H. Ingbar, Timothy P. Rich, Robert J. Schumacher, Jianxun Lei, Maneesh Bhargava
  • COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION
    Publication number: 20230050861
    Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.
    Type: Application
    Filed: August 23, 2022
    Publication date: February 16, 2023
    Inventors: David H. Ingbar, Timothy P. Rich, Robert J. Schumacher, Jianxun Lei, Maneesh Bhargava
  • Compositions and methods for treating pulmonary edema or lung inflammation
    Patent number: 11458094
    Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: October 4, 2022
    Assignee: Regents of the University of Minnesota
    Inventors: David H. Ingbar, Timothy P. Rich, Robert J. Schumacher, Jianxun Lei, Maneesh Bhargava
  • COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION
    Publication number: 20210113462
    Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.
    Type: Application
    Filed: January 31, 2019
    Publication date: April 22, 2021
    Inventors: David H. Ingbar, Timothy P. Rich, Robert J. Schumacher, Jianxun Lei, Maneesh Bhargava