Abstract: A metal heat exchanger tube having integral fins formed on the tube outside. The fins have a fin foot, fin flanks and a fin tip, and the fin foot protrudes radially from the tube wall. The tube includes a channel with a channel base and spaced-apart additional structures dividing the channel between the fins into segments and limiting fluid flow in the channel during operation. First additional structures are radially outwardly directed projections each with an end surface located between the channel base and the fin tip. Cavities in the form of second additional structures are disposed at the location of the projections between an end surface and the fin tip such that the cavities lie laterally on the fin flank and are open in the axial direction.

Abstract: Systems for differentially detecting light from a sample in a flow stream (e.g., in a flow cytometer) across one or more dimensions are described. Light detection systems according to embodiments include a flow cell configured to propagate a sample in a flow stream, a light source configured to irradiate the sample in the flow cell and a detector system having an optical adjustment component and a detector that is configured to differentially detect light from the flow cell without a scatter bar. Systems according to certain embodiments are configured to differentially detect light by modulating one or more components of the optical adjustment component or the detector. Methods for differentially detecting light from a sample in a flow stream with a detector unit without a scatter bar are also described. Kits having two or more components for use in the subject systems are also provided.

Abstract: Systems for differentially detecting light (e.g., in a flow stream) are described. Light detection systems according to certain embodiments include a plurality of photodetectors, an amplifier component and an electronic switch component having a plurality of switches in electrical communication with the plurality of photodetectors and the amplifier component. Systems and methods for differentially detecting light and optimizing the measurement of light emitted by a sample (e.g., in a flow stream) are also described. Kits having a photodetector array, an amplifier component and an electronic switch component are also provided.

Abstract: Devices, systems, and their methods of use, for detecting and/or sorting droplets or particles are provided. One or more sorters can be selected to sort droplets or particles of a desired and predictable property or droplet size. The invention involves detection of droplets or particles from a droplet or particle source through a detection region.

Abstract: Systems for detecting light (e.g., in a flow stream) are described. Light detection systems according to embodiments include two or more photodetector arrays and an optical adjustment component positioned in an optical path between the photodetector arrays. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) and kits having two or more photodetector arrays and an optical adjustment component are also provided.

Abstract: Aspects of the present disclosure include methods and systems for detecting light from a sample in a flow stream by multi-photon counting. Methods according to certain embodiments include irradiating a sample in a flow stream with a light source and detecting light from the sample in the flow stream and counting photons of the detected light by integrating photo-electron charge over a time interval. Methods also include irradiating a sample in a flow stream with a light source, detecting light from the sample in the flow stream and outputting a digital output signal and an analog output signal produced by the detected light. Systems for detecting light from a sample in a flow stream with a detector and counting photons by integrating photo-electron charge over a time interval are also described. Kits having a detector, a photon counter and a flow cell configured to propagate a sample in flow stream are also provided.

Abstract: Particle detection cartridges are provided. Aspects of the particle detection cartridges according to certain embodiments include a sample input, a flow channel and a light channel, where the flow channel and light channel are coupled at a detection region such that only light from the detection region can propagate directly through the light channel to a detector. Systems including the cartridges, as well as methods for detecting particles in a sample with the subject particle detection cartridges/systems, are also described. Kits having one or more cartridges are also provided.

Abstract: Systems for detecting light (e.g., in a flow stream) are described. Light detection systems according to embodiments include two or more photodetector arrays and an optical adjustment component positioned in an optical path between the photodetector arrays. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) and kits having two or more photodetector arrays and an optical adjustment component are also provided.

Abstract: Aspects of the present disclosure include methods and systems for detecting light from a sample in a flow stream by multi-photon counting. Methods according to certain embodiments include irradiating a sample in a flow stream with a light source and detecting light from the sample in the flow stream and counting photons of the detected light by integrating photo-electron charge over a time interval. Methods also include irradiating a sample in a flow stream with a light source, detecting light from the sample in the flow stream and outputting a digital output signal and an analog output signal produced by the detected light. Systems for detecting light from a sample in a flow stream with a detector and counting photons by integrating photo-electron charge over a time interval are also described. Kits having a detector, a photon counter and a flow cell configured to propagate a sample in flow stream are also provided.

Abstract: Systems for detecting light (e.g., in a flow stream) are described. Light detection systems according to embodiments include two or more photodetector arrays and an optical adjustment component positioned in an optical path between the photodetector arrays. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) and kits having two or more photodetector arrays and an optical adjustment component are also provided.

Abstract: Aspects of the present disclosure include methods and systems for detecting light from a sample in a flow stream by multi-photon counting. Methods according to certain embodiments include irradiating a sample in a flow stream with a light source and detecting light from the sample in the flow stream and counting photons of the detected light by integrating photo-electron charge over a time interval. Methods also include irradiating a sample in a flow stream with a light source, detecting light from the sample in the flow stream and outputting a digital output signal and an analog output signal produced by the detected light. Systems for detecting light from a sample in a flow stream with a detector and counting photons by integrating photo-electron charge over a time interval are also described. Kits having a detector, a photon counter and a flow cell configured to propagate a sample in flow stream are also provided.

Abstract: Laser assemblies are provided. Aspects of the laser assemblies according to certain embodiments include a laser, a thermoelectric cooler in contact with a bottom surface of the laser and a heat dissipation component in contact with a bottom surface of the thermoelectric cooler. Optical decks having a substrate and a laser assembly, e.g. as described above, are also provided. Methods and systems for irradiating a sample in a flow stream with the laser assembly are also provided. Aspects further include kits having a diode laser, a thermoelectric cooler and a heat dissipation component.

Abstract: Systems for differentially detecting light from a sample in a flow stream (e.g., in a flow cytometer) across one or more dimensions are described. Light detection systems according to embodiments include a flow cell configured to propagate a sample in a flow stream, a light source configured to irradiate the sample in the flow cell and a detector system having an optical adjustment component and a detector that is configured to differentially detect light from the flow cell without a scatter bar. Systems according to certain embodiments are configured to differentially detect light by modulating one or more components of the optical adjustment component or the detector. Methods for differentially detecting light from a sample in a flow stream with a detector unit without a scatter bar are also described. Kits having two or more components for use in the subject systems are also provided.

Abstract: Optical detection systems configured to collect and detect light emitted by a sample are provided. Aspects of the systems include a core region selective side scatter (SSC) collection module configured to allow for the selective detection SSC wavelength light from a core region of collected light. Also provided are methods of using the systems.

Abstract: Aspects of the present disclosure include methods and systems for detecting light from a sample in a flow stream by multi-photon counting. Methods according to certain embodiments include irradiating a sample in a flow stream with a light source and detecting light from the sample in the flow stream and counting photons of the detected light by integrating photo-electron charge over a time interval. Methods also include irradiating a sample in a flow stream with a light source, detecting light from the sample in the flow stream and outputting a digital output signal and an analog output signal produced by the detected light. Systems for detecting light from a sample in a flow stream with a detector and counting photons by integrating photo-electron charge over a time interval are also described. Kits having a detector, a photon counter and a flow cell configured to propagate a sample in flow stream are also provided.

Abstract: Aspects of the present disclosure include methods and systems for aligning a laser with a flow stream, such as in a flow cytometer. Methods according to certain embodiments include irradiating a flow stream with a laser through a wedged window, detecting light signals from the laser irradiated flow stream and aligning the laser with the flow stream by spatially adjusting the wedged window in response to the detected signal. Systems having a wedged window for aligning a laser with a flow stream are also described. Kits having a wedged window and a mount for spatially adjusting the wedged window to align a laser with a flow stream are also provided.

Abstract: Optical detection systems configured to collect and detect light emitted by a sample are provided. Aspects of the systems include a core region selective side scatter (SSC) collection module configured to allow for the selective detection SSC wavelength light from a core region of collected light. Also provided are methods of using the systems.

Abstract: Particle detection cartridges are provided. Aspects of the particle detection cartridges according to certain embodiments include a sample input, a flow channel and a light channel, where the flow channel and light channel are coupled at a detection region such that only light from the detection region can propagate directly through the light channel to a detector. Systems including the cartridges, as well as methods for detecting particles in a sample with the subject particle detection cartridges/systems, are also described. Kits having one or more cartridges are also provided.

Abstract: Systems for detecting light (e.g., in a flow stream) are described. Light detection systems according to embodiments include two or more photodetector arrays and an optical adjustment component positioned in an optical path between the photodetector arrays. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) and kits having two or more photodetector arrays and an optical adjustment component are also provided.

Abstract: An evaporation heat transfer tube has a tube main body and a step-like structure; outer fins are arranged at intervals on the outer surface of the tube main body and an inter-fin groove is formed between two adjacent outer fins; the step-like structure respectively abuts against the bottom plane and one of the side walls of the inter-fin groove. The step-like structure has a first surface, a second surface and at least one flange formed by the intersection of the two surfaces, wherein the first and the second surface intersect respectively with the side wall and the bottom plane.