Abstract: The present invention relates to a gonadotropin-releasing hormone antagonist, which has an antagonistic activity against gonadotropin-releasing hormone and can be used for the prevention or treatment of a sex hormone-dependent disease, such as benign prostatic hypertrophy, hysteromyoma, endometriosis, metrofibroma, precocious puberty, amenorrhea, premenstrual syndrome, or dysmenorrhea, or a prodrug thereof, or a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof, and a pharmaceutical composition comprising the same.

Abstract: The present disclosure provides a spectrum access method and system using prior knowledge-based double-action reinforcement learning, and belongs to the technical field of electromagnetic spectrum. The method includes evaluating and screening prior knowledge, initializing a Q-table, and confirming a current state; and performing Q-learning by: firstly, decomposing an action space into two dimensions with an action in one dimension defined as a channel chosen by an agent, and an action in the other dimension defined as a number of time slots of an access channel, and choosing actions in turn according to the dimensions; then performing spectrum access according to the actions chosen; and finally, updating the Q-table in combination with biased information, wherein the biased information is a reward value. The system is configured to implement the proposed method. By adoption of the method, better performance is achieved, and the efficiency of spectrum access can be improved.

Abstract: A dynamic spectrum sharing method based on user online learning and low-overhead cooperation is provided. In the method, a secondary user (SU) obtains spectrum sharing scene information and requirement parameters; then initializes state parameters and spectrum sensing parameters of a channel. At the beginning of each slot, the SU determines whether a direct transmission condition is met according to the transmission condition of the previous slot, and directly continues transmission on the channel of the previous slot or obtains an idle channel according to the channel state and spectrum sensing for transmission, and updates state parameter and spectrum sensing parameter. Finally, an SU base station performs conflict coordination according to the channel occupancy condition for a fixed number of slots.

Abstract: The present invention provides a dynamic spectrum sharing method based on user online learning and low-overhead cooperation, and relates to the technical field of electromagnetic spectrums. The method comprises: first, a secondary user obtaining spectrum sharing scene information and requirement parameters; then initializing a state parameter and a spectrum sensing parameter of a channel; then, at the beginning of each time slot, the secondary user determining whether a direct transmission condition is met or not according to the transmission condition of the previous time slot, selecting to directly continue transmission on the channel of the previous time slot or obtain idle channel according to the channel state and spectrum sensing for transmission, and updating the state parameter and spectrum sensing parameter of the channel; and finally, a base station of the secondary user performing conflict coordination according to the channel occupancy condition every a fixed number of time slots.

Abstract: Sustained release triptorelin microspheres include triptorelin or a salt of triptorelin, a copolymer of lactide and glycolide, and glucose or mannitol. The sustained release triptorelin microspheres have a relatively high initial release after administration, which allows the drug to produce its pharmaceutical effects immediately and to maintain long-term steady pharmaceutical effects.