Patents by Inventor Jiao YIN

Jiao YIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200340055
    Abstract: The present disclosure discloses use of TM9SF1 gene as a target in vascular diseases, which relates to the field of biotechnology. In the present disclosure, by means of RNA interference strategy, it is found that after endogenous TM9SF1 gene is interfered with, the expression of two important genes IL1? and IL8 related to the inflammation of HUVEC and the expression of the gene ACE1 closely related to vasoconstriction are remarkably downregulated, suggesting that TM9SF1 gene has positive regulation effect on the expression of IL1?, IL8 and ACE1 genes. By inhibiting or silencing the expression of the TM9SF1 gene, it is possible to inhibit or silence the expression of IL1?, IL8, and ACE1 genes, and further achieve the object of treating or preventing vascular diseases associated with the expression level of IL1?, IL8 and ACE1 genes.
    Type: Application
    Filed: July 16, 2018
    Publication date: October 29, 2020
    Inventors: Juan XIAO, Yanli HUANG, Chun MAO, Lin YANG, Jiao YIN, Xiaoming HE, Xiaofang SHEN, Wenbin DENG, Yuntao WU