Abstract: In certain aspects, provided herein are methods of inhibiting neutrophil degranulation in a patient infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by administering a composition comprising (a) a TAT-fusion protein comprising an 11 amino acid cell penetrating peptide TAT operably linked to an N-terminal SNARE domain of SNAP-23 (TAT-SNAP-23), and/or a TAT-fusion protein comprising an 11 amino acid cell penetrating peptide TAT operably linked to a SNARE domain of syn-taxin-4 (TAT-STX-4), wherein the inhibition is compared to a control.

Abstract: In certain aspects, methods are provided for treating a subject having been diagnosed with coronavirus disease 2019 (COVID-19) with a therapeutic agent that inhibits low-density inflammatory neutrophil (LDN) population expressing intermediate levels of CD 16 (CD16Int). In certain aspects, methods are provided for treating a subject having been diagnosed with coronavirus disease 2019 (COVID-19) with a therapeutic agent that inhibits CD66b+CD16IntCD11bIntCD44lowCD40+ low-density inflammatory band (LDIB) neutrophil population. In certain aspects, methods are provided for detecting the seventy level of coronavirus disease 2019 (COVID-19) in a subject, comprising measuring the level of CD16Int low-density inflammatory neutrophil (LDN) in plasma as compared to a control.

Abstract: A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment.

Abstract: A system and method for opportunity-based hygiene monitoring and/or reminding is disclosed. Healthcare providers may have various opportunities to interact with a patient. As such, an opportunity-based focus in managing a healthcare environment may assist in assessing the various opportunities when interacting with the patient. For example, an opportunity-based analysis may be used for protocol compliance, such as compliance with hand hygiene protocols and/or PPE protocols. Further, infection analysis, patient care billing, staff locating, or workload analysis may be opportunity based in order to more efficiently manage the healthcare environment.

Abstract: A system and method for detecting hand hygiene compliance is disclosed. Hand hygiene is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is integrated with or proximate to a hand cleaning agent dispenser. The interaction may be used to determine whether the healthcare provider has complied with hand hygiene protocols. Further, the wristband may be used to train healthcare providers or others (such as children) in proper hand hygiene. Further, the wristband may be used in other contexts, such as integrating hand hygiene monitoring and access control. Also, monitoring people when performing tasks, such as hygiene tasks, cooking, and moving about, may be beneficial to those with cognitive difficulties, such as dementia.

Abstract: A system and method for detecting personal protective equipment (PPE) compliance is disclosed. Personal protective equipment, such as gloves, gowns, masks, protective eyewear, may be used to limit transmission of illness either from the patient to the care giver or vice-versa. Compliance with PPE is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is associated with an entrance and/or an exit to an area for the patient (such as the stationary controller integrated with or proximate to a hand cleaning agent dispenser) proximate to the entrance and/or exit. The interaction may be used to determine whether the healthcare provider has complied with PPE protocols. Further, the system may be used to train healthcare providers or others in PPE hygiene.

Abstract: A system and method for detecting hand hygiene compliance is disclosed. Hand hygiene is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is integrated with or proximate to a hand cleaning agent dispenser. The interaction may be used to determine whether the healthcare provider has complied with hand hygiene protocols. Further, the wristband may be used to train healthcare providers or others (such as children) in proper hand hygiene. Further, the wristband may be used in other contexts, such as integrating hand hygiene monitoring and access control. Also, monitoring people when performing tasks, such as hygiene tasks, cooking, and moving about, may be beneficial to those with cognitive difficulties, such as dementia.

Abstract: A system and method for detecting hand hygiene compliance is disclosed. Hand hygiene is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is integrated with or proximate to a hand cleaning agent dispenser. The interaction may be used to determine whether the healthcare provider has complied with hand hygiene protocols. Further, the wristband may be used to train healthcare providers or others (such as children) in proper hand hygiene. Further, the wristband may be used in other contexts, such as integrating hand hygiene monitoring and access control. Also, monitoring people when performing tasks, such as hygiene tasks, cooking, and moving about, may be beneficial to those with cognitive difficulties, such as dementia.

Abstract: A system and method for detecting personal protective equipment (PPE) compliance is disclosed. Personal protective equipment, such as gloves, gowns, masks, protective eyewear, may be used to limit transmission of illness either from the patient to the care giver or vice-versa. Compliance with PPE is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is associated with an entrance and/or an exit to an area for the patient (such as the stationary controller integrated with or proximate to a hand cleaning agent dispenser) proximate to the entrance and/or exit. The interaction may be used to determine whether the healthcare provider has complied with PPE protocols. Further, the system may be used to train healthcare providers or others in PPE hygiene.

Abstract: A system and method for detecting hand hygiene compliance is disclosed. Hand hygiene is important in various contexts, including hospital settings, home settings, work settings, and school settings. For example, a healthcare provider may wear a wristband, which may interact with a stationary controller that is integrated with or proximate to a hand cleaning agent dispenser. The interaction may be used to determine whether the healthcare provider has complied with hand hygiene protocols. Further, the wristband may be used to train healthcare providers or others (such as children) in proper hand hygiene. Further, the wristband may be used in other contexts, such as integrating hand hygiene monitoring and access control. Also, monitoring people when performing tasks, such as hygiene tasks, cooking, and moving about, may be beneficial to those with cognitive difficulties, such as dementia.