Abstract: Provided herein are bioactive molecule conjugates, preparation methods and use thereof, particularly bioactive molecule conjugates (such as antibody-drug conjugates and small molecule drug conjugates) obtained by improved coupling of a drug and a targeting moiety, as well as their preparation method and use for the treatment of a disease associated with an abnormal cell activity.

Abstract: An anode catalyst layer with high reversal tolerant capability includes an anode inner catalyst layer close to a proton exchange membrane and an anode outer catalyst layer close to a gas diffusion layer. At least the anode inner catalyst layer contains a reversal tolerant catalyst and a hydrophilic additive. The content of the hydrophilic additive in the anode inner catalyst layer is not less than that of the anode outer catalyst layer, or the water retention capability of the anode inner catalyst layer is not less than that of the anode outer catalyst layer.

Abstract: The invention relates to the field of fuel cells, and in particular to a method for preparing highly stable catalyst coating slurry for fuel cells. The method for preparing highly stable catalyst coating slurry for fuel cells, includes at least two mixing and dispersing steps. The first mixing and dispersing step is carried out to mix and disperse the catalyst, perfluorosulfonic acid resin and solvent to obtain a first-stage mixed dispersion, and the other mixing and dispersing steps are carried out to mix and disperse the previous-stage mixed dispersion and the newly added perfluorosulfonic acid resin, wherein at least one mixing and dispersing step has a surfactant is added for mixing and dispersing. The catalyst in the catalyst slurry prepared by the method has good dispersion stability and less sedimentation, and good performance is achieved when the catalyst slurry is applied to membrane electrodes.