Abstract: The present invention relates to the field of biomedicine, to an improved T cell receptor-costimulatory molecule chimera, in particular to a T cell receptor (TCR) or TCR complex comprising a costimulatory molecule, a T cell comprising the TCR or TCR complex, and the use thereof.

Abstract: The disclosure relates to KRASG12D inhibitor compounds having the structure of Formula (A) or Formula (B), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRASG12D mutation-associated diseases, disorders and conditions.

Abstract: A speaker includes: a frame, a vibration system, including a diaphragm and a voice coil driving the diaphragm to vibrate and emit sounds, and a magnetic circuit system fixed to the frame, including a lower plate, and a central magnetic portion and an auxiliary magnet fixed to the lower plate, the central magnetic portion spaced apart from the auxiliary magnet, the auxiliary magnet surrounding the central magnetic portion and forming a magnetic gap, the voice coil located in the magnetic gap, wherein the central magnetic portion includes a main magnetic portion and a reinforcing portion surrounding the main magnetic portion, a projection of the voice coil in a vibration direction of the diaphragm is at least partially located in the reinforcing portion. Compared with the related art, the speaker disclosed by the present disclosure could improve the BL value of the voice coil.

Abstract: A speaker includes: a frame, a vibration system, including a diaphragm and a voice coil assembly, and a magnetic circuit system, comprising a lower plate, a first main magnet and a first auxiliary magnet, a main pole plate, and an upper plate, wherein the upper plate includes a body portion and a groove recessed from the body portion to the lower plate, the groove includes a base, and a connecting arm connected with the body portion and the base, the base is closer to the body portion than the lower plate, the speaker further includes a second auxiliary magnet located in the groove, the base is clamped between the first auxiliary magnet and the second auxiliary magnet. Compared with the related art, the speaker disclosed by the present disclosure could improve the BL value of the voice coil.

Abstract: The present disclosure discloses a sound device comprising: a frame; a vibration system supported on the frame; a magnetic system driving the vibration system for sound generation supported on the frame; the magnetic system comprises a main magnet, a sub-magnet and a magnetic gap formed by spacing of the main magnet and the sub-magnet; the vibration system includes a diaphragm fixed to the frame and a coil driving the diaphragm for sound generation, the coil is at least partially inserted in the magnetic gap; the coil includes a first coil and a second coil both in a shape of ring, one end of the first coil is fixed to the side of the diaphragm near the magnetic system, one end of the second coil is fixed to the end of the first coil near the magnetic system, and the first coil and the second coil are insulated from each other. The present disclosure provides a sound device with adjustable voice coil position and good acoustic performance.

Abstract: The present disclosure provides a speaker unit, which includes a frame, and a vibration system and a magnetic circuit system fixed on the frame. The vibration system includes a diaphragm and a voice coil that drives the diaphragm to vibrate and sound. The speaker unit further includes a magnetic front cover fixed on the frame for improving the BL value of the voice coil. The speaker unit of the present disclosure improves the BL value of the voice coil.

Abstract: The present disclosure provides a sound device which includes a vibration system, a magnetic circuit system, and a basket that accommodates the vibration system and the magnetic circuit system. The vibration system includes a diaphragm and a voice coil that drives the diaphragm to vibrate. The fixing portion includes a first fixing portion fixed to the upper surface and extending to an edge of the upper surface and a second fixing portion extending from the first fixing portion and along the outer side surface. The second fixing portion in a continuous ring shape is around an end of the outer side surface close to the upper surface in a sealing manner, and a thickness of the second fixing portion is increasing in a direction away from the upper surface.

Abstract: A sounding device includes a holder, a magnetic circuit unit, and an elastic sheet fixing the magnetic circuit unit to the holder. The magnetic circuit unit includes a yoke, a main magnet fixed to the yoke, at least two auxiliary magnets disposed around two opposite sides of the main magnet, and an upper clamping plate respectively covering and fixed to the auxiliary magnets. One end of the elastic sheet is fixed to the holder, and the other end of the elastic sheet is fixed to the upper clamping plate.

Abstract: The present disclosure provides a micro sound device. The micro sound device includes a basket having an accommodating space, a vibration system secured to the basket, and a magnetic circuit system accommodated in the basket and configured to drive the vibration system to vibrate and produce sound. The vibration system includes an upper diaphragm secured to the basket, a voice coil located below the upper diaphragm and configured to drive the upper diaphragm to vibrate and produce sound, and a support apparatus elastically supporting the voice coil. The support apparatus is disposed opposite to the upper diaphragm and separately from the upper diaphragm. The magnetic circuit system includes an upper clamping plate secured to the basket. One end of the support apparatus is fixed to one side of the upper clamping plate and the other end of the support apparatus is fixed to the voice coil.

Abstract: A multi-function speaker includes a frame having a receiving space, a magnetic circuit system, a vibration system, and an elastic member configured to suspend the magnetic circuit system in the receiving space. The frame includes two first side portions oppositely arranged, and two oppositely disposed second side portions connecting the two first side portions. The magnetic circuit system includes a lower plate, and a magnet assembly disposed on the lower plate.

Abstract: The present invention provides a sound generator, includes a frame with an accommodating space, a magnetic circuit system and a vibration system. The magnetic yoke includes a bottom wall, a side wall and a supporting plate bending and extending from the side wall. The frame includes an upper surface close to the diaphragm and a lower surface provided with a fixing post. The spring includes an inner edge close to the accommodating space and an outer edge opposite to the inner edge and far away from the accommodation space. The fixing post is provided between the inner edge of the spring and the side wall. Compared to the relate art, the spring of the present invention can make more effective use of space, ensure the spring size, thus reducing the low-frequency response of the sound generator to further improve the acoustic performance.

Abstract: The present disclosure provides a multi-function speaker, which includes a frame having a housing space, a magnetic circuit system and a vibration system accommodated in the housing space, an elastic body configured to suspend the magnetic circuit system in the housing space of the frame. The elastic body fixed to the frame includes two elastic pieces having the same structure. The magnetic circuit system comprises a lower plate, a primary magnet, a secondary magnet and an upper plate disposed on the secondary magnet. The upper plate includes a protrusion, the elastic piece includes a first fixed portion fixedly connected to the first side wall, a second fixed portion fixedly connected to the protrusion, and an elastic portion.

Abstract: The present disclosure provides a multi-function speaker, which includes a frame having a housing space, a magnetic circuit system and a vibration system accommodated in the housing space, an elastic body configured to suspend the magnetic circuit system in the housing space of the frame. The elastic body fixed to the frame includes two elastic pieces having the same structure. The magnetic circuit system comprises a lower plate, a primary magnet, a secondary magnet and an upper plate disposed on the secondary magnet. The upper plate includes a protrusion, the elastic piece includes a first fixed portion fixedly connected to the first side wall, a second fixed portion fixedly connected to the protrusion, and an elastic portion.

Abstract: A multi-function speaker includes a frame having a receiving space, a magnetic circuit system, a vibration system, and an elastic member configured to suspend the magnetic circuit system in the receiving space. The frame includes two first side portions oppositely arranged, and two oppositely disposed second side portions connecting the two first side portions. The magnetic circuit system includes a lower plate, and a magnet assembly disposed on the lower plate.

Abstract: A sounding device includes a holder, a magnetic circuit unit, and an elastic sheet fixing the magnetic circuit unit to the holder. The magnetic circuit unit includes a yoke, a main magnet fixed to the yoke, at least two auxiliary magnets disposed around two opposite sides of the main magnet, and an upper clamping plate respectively covering and fixed to the auxiliary magnets. One end of the elastic sheet is fixed to the holder, and the other end of the elastic sheet is fixed to the upper clamping plate.

Abstract: The present disclosure provides a sound device which includes a vibration system, a magnetic circuit system, and a basket that accommodates the vibration system and the magnetic circuit system. The vibration system includes a diaphragm and a voice coil that drives the diaphragm to vibrate. The fixing portion includes a first fixing portion fixed to the upper surface and extending to an edge of the upper surface and a second fixing portion extending from the first fixing portion and along the outer side surface. The second fixing portion in a continuous ring shape is around an end of the outer side surface close to the upper surface in a sealing manner, and a thickness of the second fixing portion is increasing in a direction away from the upper surface.

Abstract: The present disclosure provides a micro sound device. The micro sound device includes a basket having an accommodating space, a vibration system secured to the basket, and a magnetic circuit system accommodated in the basket and configured to drive the vibration system to vibrate and produce sound. The vibration system includes an upper diaphragm secured to the basket, a voice coil located below the upper diaphragm and configured to drive the upper diaphragm to vibrate and produce sound, and a support apparatus elastically supporting the voice coil. The support apparatus is disposed opposite to the upper diaphragm and separately from the upper diaphragm. The magnetic circuit system includes an upper clamping plate secured to the basket. One end of the support apparatus is fixed to one side of the upper clamping plate and the other end of the support apparatus is fixed to the voice coil.

Abstract: The present invention provides a sound generator, includes a frame with an accommodating space, a magnetic circuit system and a vibration system. The magnetic yoke includes a bottom wall, a side wall and a supporting plate bending and extending from the side wall. The frame includes an upper surface close to the diaphragm and a lower surface provided with a fixing post. The spring includes an inner edge close to the accommodating space and an outer edge opposite to the inner edge and far away from the accommodation space. The fixing post is provided between the inner edge of the spring and the side wall. Compared to the relate art, the spring of the present invention can make more effective use of space, ensure the spring size, thus reducing the low-frequency response of the sound generator to further improve the acoustic performance.

Abstract: A speaker is provided in the present disclosure. The speaker includes a holder, a magnetic system received in the holder, a vibration system having a membrane and a voice coil for driving the membrane to vibrate, and an elastic member for suspending the magnetic system in the holder and enabling the magnetic system to vibrate along a vibration direction of the membrane. The elastic member includes a supporting part for supporting the magnetic system, a plurality of elastic arms extending from the supporting part, and a plurality of fixing parts fixed to the holder. Each of the elastic arms extends in a plane perpendicular to the vibration direction of the membrane in a wavy manner.