Patents by Inventor Jiashu LI
Jiashu LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240100342Abstract: Devices, systems, and techniques are described that use electric field imaging (often referred to as the sensed stimulation artifact representative of a delivered stimulus) as an informative feedback signal to provide closed loop control of electrical stimulation therapy. In some examples, the electric field imaging may be used in combination with other feedback signals, such as ECAP do monitor and adjust the delivered electrical stimulation therapy.Type: ApplicationFiled: February 23, 2022Publication date: March 28, 2024Inventors: Jerel K. Mueller, Leonid M. Litvak, Vinod Sharma, Katelynn M. Johnson, Jiashu Li
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Publication number: 20240042210Abstract: Systems, devices, methods, and techniques are described for using evoked compound action potential (ECAP) signals to monitor lead position and/or detect lead migration. An example system includes sensing circuitry configured to sense an ECAP signal, and processing circuitry. The processing circuitry controls the sensing circuitry to detect, after delivery of an electrical stimulation pulse, a current ECAP signal, and determines one or more characteristics of the current ECAP signal. The processing circuitry also compares the one or more characteristics of the current ECAP signal to corresponding one or more characteristics of a baseline ECAP signal, and determines, based on the comparison, a migration state of the electrodes delivering the electrical stimulation pulse. Additionally, the processing circuitry outputs, based on the migration state, an alert indicative of migration of the electrodes.Type: ApplicationFiled: October 16, 2023Publication date: February 8, 2024Inventors: Jiashu Li, David A. Dinsmoor, Duane L. Bourget, Kristin N. Hageman, Hank Bink, Christopher L. Pulliam
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Publication number: 20230364425Abstract: Processing circuitry of a system configured to determine a patient state based on sensed signals including posture and activity information and control delivery of electrical stimulation therapy to the patient via electrodes implanted proximal to target tissue of the patient. The sensed signals also include impedance measurement, and other bioelectrical signals, where sensing is interleaved with the electrical stimulation therapy. Responsive to determining the patient state, select an action, wherein the selected action comprises one or more of: store collected information, upload the collected information to an external computing device, and output an electronic signal comprising an alert.Type: ApplicationFiled: April 21, 2023Publication date: November 16, 2023Inventors: Hank T. Bink, Erik J. Peterson, Jiashu Li, Vinod Sharma, Juan G. Hincapie, Eric J. Panken, Leonid M. Litvak, David A. Dinsmoor, Todd D. Zenisek, Andrew L. Schmeling, Andrew J. Cleland
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Publication number: 20230364427Abstract: Processing circuitry for a medical system configured to sense bioelectrical signals and determine posture and activity information as well as information about the environment of the patient. The processing circuitry is also configured to control stimulation generation circuitry to deliver the electrical stimulation therapy, and interleaved with the electrical stimulation therapy, control the stimulation generation circuitry to output an impedance measurement signal. The processing circuitry is further configured to determine respiration of the patient based on the impedance. Responsive to determining the respiration of the patient, the processing circuitry may then determine a patient state based on the determined respiration, and the posture and activity information of the patient.Type: ApplicationFiled: April 21, 2023Publication date: November 16, 2023Inventors: Hank T. Bink, Erik J. Peterson, Jiashu Li, Vinod Sharma, Juan G. Hincapie, Eric J. Panken, Leonid M. Litvak, David A. Dinsmoor, Todd D. Zenisek, Andrew L. Schmeling, Andrew J. Cleland
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Patent number: 11791822Abstract: Provided are a programmable device for processing a data set, and a method for processing a data set. The programmable device includes a plurality of accumulation circuits, wherein each of the accumulation circuits includes a pipeline adder and a cache unit for storing a computation result of the pipeline adder; and a multiplexer for receiving in sequence data in a data set, dynamically determining a correlation between a plurality of features included in the data and the plurality of accumulation circuits, and respectively sending, according to the correlation, feature values of the plurality of features in the received data to corresponding accumulation circuits.Type: GrantFiled: June 12, 2020Date of Patent: October 17, 2023Assignee: THE FOURTH PARADIGM (BEIJING) TECH CO LTDInventors: Jiashu Li, Mian Lu, Cheng Ji, Jun Yang
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Patent number: 11786734Abstract: Systems, devices, methods, and techniques are described for using evoked compound action potential (ECAP) signals to monitor lead position and/or detect lead migration. An example system includes sensing circuitry configured to sense an ECAP signal, and processing circuitry. The processing circuitry controls the sensing circuitry to detect, after delivery of an electrical stimulation pulse, a current ECAP signal, and determines one or more characteristics of the current ECAP signal. The processing circuitry also compares the one or more characteristics of the current ECAP signal to corresponding one or more characteristics of a baseline ECAP signal, and determines, based on the comparison, a migration state of the electrodes delivering the electrical stimulation pulse. Additionally, the processing circuitry outputs, based on the migration state, an alert indicative of migration of the electrodes.Type: GrantFiled: August 7, 2020Date of Patent: October 17, 2023Assignee: Medtronic, Inc.Inventors: Jiashu Li, David A. Dinsmoor, Duane L. Bourget, Kristin N. Hageman, Hank Bink, Christopher L. Pulliam
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Publication number: 20230302281Abstract: In one example, the disclosure describes a method comprising receiving, by processing circuitry, information indicative of one or more evoked compound action potential (ECAP) signals. The one or more ECAP signals are sensed by at least one electrode carried by a medical lead. The processing circuitry determining that at least one characteristic value of the one or more ECAP signals is outside of an expected range. Responsive to determining that the at least one characteristic value of the one or more ECAP signals is outside of the expected range, the processing circuitry performs a lead integrity test for the medical lead.Type: ApplicationFiled: April 27, 2023Publication date: September 28, 2023Inventors: Jiashu Li, Duane L. Bourget, Kristin N. Hageman, Hank Bink
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Publication number: 20230233861Abstract: Techniques are disclosed for using a cardiac signal sensed via a plurality of electrodes disposed on one or more leads implanted within an epidural space of a patient to control spinal cord stimulation (SCS) therapy. In one example, an implantable medical device (IMD) senses an electrical signal via a plurality of electrodes disposed on one or more leads implanted within an epidural space of a patient. Processing circuitry determines, from the electrical signal, one or more cardiac features indicative of activity of a heart of the patient. The processing circuitry controls, based on the one or more cardiac features, delivery of SCS therapy to the patient.Type: ApplicationFiled: March 29, 2023Publication date: July 27, 2023Inventors: Jiashu Li, Jeffery Kramer, Vinod Sharma
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Patent number: 11648402Abstract: In one example, the disclosure describes a method comprising receiving, by processing circuitry, information indicative of one or more evoked compound action potential (ECAP) signals. The one or more ECAP signals are sensed by at least one electrode carried by a medical lead. The processing circuitry determining that at least one characteristic value of the one or more ECAP signals is outside of an expected range. Responsive to determining that the at least one characteristic value of the one or more ECAP signals is outside of the expected range, the processing circuitry performs a lead integrity test for the medical lead.Type: GrantFiled: September 30, 2020Date of Patent: May 16, 2023Assignee: Medtronic, Inc.Inventors: Jiashu Li, Duane L. Bourget, Kristin N. Hageman, Hank Bink
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Patent number: 11642531Abstract: Techniques are disclosed for using a cardiac signal sensed via a plurality of electrodes disposed on one or more leads implanted within an epidural space of a patient to control spinal cord stimulation (SCS) therapy. In one example, an implantable medical device (IMD) senses an electrical signal via a plurality of electrodes disposed on one or more leads implanted within an epidural space of a patient. Processing circuitry determines, from the electrical signal, one or more cardiac features indicative of activity of a heart of the patient. The processing circuitry controls, based on the one or more cardiac features, delivery of SCS therapy to the patient.Type: GrantFiled: October 9, 2020Date of Patent: May 9, 2023Assignee: MEDTRONIC, INC.Inventors: Jiashu Li, Jeffery Kramer, Vinod Sharma
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Patent number: 11627913Abstract: An example method includes obtaining an image of a lead implanted in a patient, the lead including one or more electrodes positioned along a longitudinal axis of the lead and a plurality of orientation markers; determining, in the image, respective locations of the electrodes and respective locations of the orientation markers; obtaining a template model corresponding to the lead; determining a transform between the determined locations of the one or more electrodes and the plurality of orientation markers and locations of corresponding electrodes and orientation markers in the template model; and determining the rotational orientation of the lead based on the transform.Type: GrantFiled: April 25, 2019Date of Patent: April 18, 2023Assignee: MEDTRONIC, INC.Inventors: Shai Ronen, Andre D. A. Souza, Jiashu Li, Patrick A. Helm
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Stimulation lead with electrodes configured for sensing and stimulation over a partial circumference
Patent number: 11559258Abstract: A lead body is operable to be implanted proximate a target nerve tissue of a patient. A sensing electrode is configured to sense biopotentials over a first partial circumference of the lead body. A stimulation electrode is configured to deliver stimulation energy over a second partial circumference of the lead body. A signal generator is electrically coupled to the stimulation electrode and a sensing circuit is coupled to the sensing electrode. A processor is operable to apply a stimulation signal to the stimulation electrode via the signal generator and, via the sensing circuit, sense an evoked response to the stimulation signal that propagates along a neural pathway.Type: GrantFiled: April 30, 2020Date of Patent: January 24, 2023Assignee: MEDTRONIC, INC.Inventors: David A. Dinsmoor, Jiashu Li -
Publication number: 20230001208Abstract: Systems, devices, and techniques are described for determining a posture state of a patient based on detected evoked compound action potentials (ECAPs). In one example, a medical device includes stimulation circuitry configured to deliver electrical stimulation and sensing circuitry configured to sense a plurality of evoked compound action potential (ECAP) signals. The medical device also includes processing circuitry configured to control the stimulation circuitry to deliver a plurality of electrical stimulation pulses having different amplitude values, control the sensing circuitry to detect, after delivery of each electrical stimulation pulse of the plurality of electrical stimulation pulses, a respective ECAP signal of the plurality of ECAP signals, and determine, based on the plurality of ECAP signals, a posture state of the patient.Type: ApplicationFiled: September 12, 2022Publication date: January 5, 2023Inventors: David A. Dinsmoor, Christopher L. Pulliam, Kristin N. Hageman, Hank Bink, Jiashu Li
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Stimulation lead with electrodes configured for sensing and stimulation over a partial circumference
Patent number: 11491326Abstract: A lead body is operable to be implanted proximate a target nerve tissue of a patient. A sensing electrode is configured to sense biopotentials over a first partial circumference of the lead body. A stimulation electrode is configured to deliver stimulation energy over a second partial circumference of the lead body. A signal generator is electrically coupled to the stimulation electrode and a sensing circuit is coupled to the sensing electrode. A processor is operable to apply a stimulation signal to the stimulation electrode via the signal generator and, via the sensing circuit, sense an evoked response to the stimulation signal that propagates along a neural pathway.Type: GrantFiled: April 30, 2020Date of Patent: November 8, 2022Assignee: Medtronic, Inc.Inventors: David A. Dinsmoor, Jiashu Li, Andrew L. Schmeling -
Patent number: 11439825Abstract: Systems, devices, and techniques are described for determining a posture state of a patient based on detected evoked compound action potentials (ECAPs). In one example, a medical device includes stimulation circuitry configured to deliver electrical stimulation and sensing circuitry configured to sense a plurality of evoked compound action potential (ECAP) signals. The medical device also includes processing circuitry configured to control the stimulation circuitry to deliver a plurality of electrical stimulation pulses having different amplitude values, control the sensing circuitry to detect, after delivery of each electrical stimulation pulse of the plurality of electrical stimulation pulses, a respective ECAP signal of the plurality of ECAP signals, and determine, based on the plurality of ECAP signals, a posture state of the patient.Type: GrantFiled: December 19, 2019Date of Patent: September 13, 2022Assignee: Medtronic, Inc.Inventors: David A. Dinsmoor, Christopher L. Pulliam, Kristin N. Hageman, Hank Bink, Jiashu Li
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Publication number: 20220266028Abstract: An example method of cycling electric stimulation includes delivering, via an implantable device, electric stimulation to a patient in accordance with a first therapy program; monitoring, via the implantable device and while the electric stimulation is being delivered in accordance with the first therapy program, a biomarker; and responsive to determining the biomarker satisfies a threshold, delivering, via the implantable device, electric stimulation to the patient in accordance with a second therapy program that is different than the first therapy program.Type: ApplicationFiled: February 18, 2022Publication date: August 25, 2022Inventors: Hank Bink, Erik J. Peterson, Louis Vera-Portocarrero, Vinod Sharma, Jiashu Li
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Patent number: 11420058Abstract: A system comprises a bendable, pre-formed lead body operable to be implanted proximate a neural pathway of a patient. A first electrode comprising a plurality of first segments at a first longitudinal location of the lead body is configured to be positioned at a lateral epidural region proximate at least one nerve root of the patient, and a second electrode comprising a plurality of second segments at a second longitudinal location of the lead body is configured to be positioned along a midline of the patient's spinal column. The system further includes a signal generator electrically coupled to at least one of the first and second electrodes and a processor coupled to the signal generator and operable to apply a stimulation signal to at least one of the first and second electrodes.Type: GrantFiled: October 30, 2020Date of Patent: August 23, 2022Assignee: Medtronic, Inc.Inventors: Andrew Jay Cleland, Melanie D. Goodman Keiser, Louis Vera-Portocarrero, Phillip C. Falkner, Brooke Kelley, Jiashu Li
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Publication number: 20220257929Abstract: A sleeve for a medical lead includes a tubular body having a first open end and a second open end, a tubular wall extending between the first and second ends and defining a hollow center, and a longitudinal axis extending through the hollow center. A first pocket is disposed in the tubular wall and having a curved transverse cross section and a first access opening at the first open end of the tubular body. A medical lead system includes a medical lead and the sleeve configured to slide over the medical lead and be adjacent to the electrode region.Type: ApplicationFiled: May 2, 2022Publication date: August 18, 2022Inventors: Jiashu Li, Patrick Helm, Sean P. Skubitz, Ashutosh Chaturvedi
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Publication number: 20220149843Abstract: Provided are a programmable device for processing a data set, and a method for processing a data set. The programmable device includes a plurality of accumulation circuits, wherein each of the accumulation circuits includes a pipeline adder and a cache unit for storing a computation result of the pipeline adder; and a multiplexer for receiving in sequence data in a data set, dynamically determining a correlation between a plurality of features included in the data and the plurality of accumulation circuits, and respectively sending, according to the correlation, feature values of the plurality of features in the received data to corresponding accumulation circuits.Type: ApplicationFiled: June 12, 2020Publication date: May 12, 2022Inventors: Jiashu LI, Mian LU, Cheng JI, Jun YANG
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Publication number: 20220134109Abstract: A system comprises a bendable, pre-formed lead body operable to be implanted proximate a neural pathway of a patient. A first electrode comprising a plurality of first segments at a first longitudinal location of the lead body is configured to be positioned at a lateral epidural region proximate at least one nerve root of the patient, and a second electrode comprising a plurality of second segments at a second longitudinal location of the lead body is configured to be positioned along a midline of the patient's spinal column. The system further includes a signal generator electrically coupled to at least one of the first and second electrodes and a processor coupled to the signal generator and operable to apply a stimulation signal to at least one of the first and second electrodes.Type: ApplicationFiled: October 30, 2020Publication date: May 5, 2022Inventors: Andrew Jay Cleland, Melanie D. Goodman Keiser, Louis Vera-Portocarrero, Phillip C. Falkner, Brooke Kelley, Jiashu Li