Abstract: Provided are a compound used as a BCR-ABL inhibitor, namely a compound of formula (I), or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition comprising the compound. Moreover, the present invention relates to a use of the compound in the preparation of a drug for treating BCR-ABL related diseases.

Abstract: The present invention discloses a 3D positioning apparatus for an underwater high-pressure water decontamination nozzle, which comprises a variable length water gun, a high-pressure water nozzle fixed to a front end of a gun barrel of the variable length water gun by a nozzle quick lock, and a high-pressure water intake pipe connected to a rear end of the gun barrel, the gun barrel being fixed to a gun body by a water gun quick lock, and further comprises an underwater sonar 3D positioning unit arranged on the gun body, The underwater sonar 3D positioning unit comprises a sonar signal generator, a power amplifier, a sonar having one transmitting unit and three receiving units distributed equidistantly along a circumference thereof, a signal amplifier, a distance identification and correction module, a temperature and salinity measurement module, and an alarm apparatus in circuit connection.