Abstract: A valve includes a valve body, a valve plate, and an actuation mechanism, wherein the valve body includes two plates parallel to each other and symmetrical and on which medium access holes are correspondingly opened; sealing rings a are symmetrically provided on inner surfaces of the two plates, and the medium access holes on the two plates are completely located within circumferentially closed holes of the sealing rings a; the valve plate has a smooth surface and is tightly sandwiched between the sealing rings a when the valve is closed; a fastening structure is installed on the two plates of the valve body and clamps the two plates and/or the sealing rings a around radial peripheries of the sealing rings a; and at least a part of the fastening structure can adjust its clamping degree in a direction perpendicular to a surface of the valve body.

Abstract: The present invention provides a full-automatic cell production line, comprising a culture region and an operation region. The culture region comprises a B-stage platform body, and the B-stage platform body comprises a culture area, a refrigeration area, and a robot provided with a motion track. The motion track of the robot is linearly arranged. The culture area, the refrigeration area, and a manual delivery window all surround the track, and are all located in the operation region of the robot. The operation region is integrated with a liquid storage table, a cell factory liquid changing device, and a centrifugal bottle liquid changing device. The delivery window is used between the culture region and the operation region to deliver a material. The technical solution of the present invention is mainly used for full-automatic batch production of cells.

Abstract: Provided are a cardiomyocyte preparation, a preparation method therefor and the use of the preparation in treating heart failure. The cardiomyocyte preparation comprises cardiomyocytes and fibroblasts, differentiated from pluripotent stem cells, wherein the concentration of the cardiomyocytes in the cardiomyocyte preparation is 0.75×107-1.0×109 cells/mL, and the content of the cardiomyocytes is higher than 80% while the content of the fibroblasts is not higher than 20%. The cardiomyocyte preparation can improve cardiac ejection fraction and left ventricular fractional shortening, and increase the thickness of the left ventricular inner wall.

Abstract: A valve includes a valve body, a valve plate, and an actuation mechanism, wherein the valve body includes two plates parallel to each other and symmetrical and on which medium access holes are correspondingly opened; sealing rings a are symmetrically provided on inner surfaces of the two plates, and the medium access holes on the two plates are completely located within circumferentially closed holes of the sealing rings a; the valve plate has a smooth surface and is tightly sandwiched between the sealing rings a when the valve is closed; a fastening structure is installed on the two plates of the valve body and clamps the two plates and/or the sealing rings a around radial peripheries of the sealing rings a; and at least a part of the fastening structure can adjust its clamping degree in a direction perpendicular to a surface of the valve body.

Abstract: The present invention provides a full-automatic cell production line, comprising a culture region and an operation region. The culture region comprises a B-stage platform body, and the B-stage platform body comprises a culture area, a refrigeration area, and a robot provided with a motion track. The motion track of the robot is linearly arranged. The culture area, the refrigeration area, and a manual delivery window all surround the track, and are all located in the operation region of the robot. The operation region is integrated with a liquid storage table, a cell factory liquid changing device, and a centrifugal bottle liquid changing device. The delivery window is used between the culture region and the operation region to deliver a material. The technical solution of the present invention is mainly used for full-automatic batch production of cells.

Abstract: Provided is a membrane for cell culture and differentiation. The membrane comprises a base portion and an array of protrusions consisting of a plurality of protrusions. The protrusions are substantially evenly distributed on the base portion. The plurality of protrusions has dimensions on the order of micrometers. In particular, the membrane consists of particles of different particle sizes of two or more types. One type of particles has an average particle size of 1 ?m to 50 ?m. Two or more types of particles of different particle sizes include nanoscale particles, 10-900 nm. One type of particle is selected from the group consisting of inorganic compound microspheres. The other type of particles of the two or more types of particles of different particle sizes is selected from the group consisting of organic polymer nanospheres. Also provided is a method for maintaining, culturing and/or differentiating cells using such membrane.

Abstract: Provided is a scalable battery module. In once example embodiment, the module includes a plurality of submodules. Each plurality of submodules is configured to hold one or more cell batteries. The module further includes one or more of a first connector, a second connector, or a third connector. The first connector may secure an alignment of two or more adjacent submodules of the plurality of submodules along a first dimensional axis by using at least one of two slots and two projections of the first connector. The second connector secures the alignment of two adjacent submodules of the plurality of submodules along a second dimensional axis by using at least two further slots of the second connector. The third connector secures the alignment of two adjacent submodules of the plurality of submodules along a third dimensional axis by using at least two further projections of the third connector.

Abstract: Various arrangements for a battery module cooling system are presented. A thermal tower may be contoured to contact one or more battery cells. The thermal tower may include a holding member and a cooling member. A hollow interior region having a top aperture may be defined by the holding member. A portion of each of the one or more battery cells may be contacted by the cooling member to provide localized cooling to each of the one or more battery cells. A seal may be formed between the holding member and the cooling member by positioning the cooling member on the top aperture of the holding member. Optionally, the portion that the cooling members may contact to provide localized cooling may include a hot region having a higher temperature than other portions of each of the one or more battery cells.

Abstract: Apparatuses, systems, and methods of providing electric power to components in electric vehicles are detailed herein. A housing can have a bottom panel and side walls defining a cavity. The bottom panel can define an inlet port and an outlet port. A battery module can be disposed within the cavity. A support structure can be on one side wall. The support structure can have a conduit to pass coolant through the housing. A cold plate can be disposed within the cavity and thermally coupled with the battery module. The cold plate can have an inlet, an outlet, and a channel to circulate the coolant from the inlet to the outlet. A distribution plate can be disposed along a bottom surface of the bottom panel. The distribution plate can have a main channel to convey the coolant from the conduit to the cold plate.

Abstract: Disclosed are a medium for differentiating neural stem cells into oligodendrocyte precursors and a method for preparing oligodendrocyte precursors by using the medium. The medium does not contain exogenous factors, and can avoid the contamination of exogenous factors and differentiate oligodendrocyte precursors.

Abstract: Apparatuses, systems, and methods to provide electrical power to components in electric vehicles are described herein. A battery pack can be arranged in a first position within an interior opening defined by a lateral member. A connecting member can be coupled with the battery pack, and can have a head and a body. A panel can be disposed along the lateral member, and can have a top and bottom layer. The top layer can define an opening to pass the head and body. The bottom layer can define an opening to support the head. A plate can be disposed on the top layer and can define an opening. The opening of the plate can have a first region to hold the battery pack in the first position and a second region to allow the battery pack to move to a second position outside the interior opening responsive to an impact.

Abstract: Provided are a cardiomyocyte preparation, a preparation method therefor and the use of the preparation in treating heart failure. The cardiomyocyte preparation comprises cardiomyocytes and fibroblasts, differentiated from pluripotent stem cells, wherein the concentration of the cardiomyocytes in the cardiomyocyte preparation is 0.75×107-1.0×109 cells/mL, and the content of the cardiomyocytes is higher than 80% while the content of the fibroblasts is not higher than 20%. The cardiomyocyte preparation can improve cardiac ejection fraction and left ventricular fractional shortening, and increase the thickness of the left ventricular inner wall.

Abstract: Provided is a membrane for cell culture and differentiation. The membrane has a base portion and an array of protrusions consisting of a plurality of protrusions. The protrusions are substantially evenly distributed on the base portion. The plurality of protrusions has dimensions on the order of micrometers. In particular, the membrane consists of particles of different particle sizes of two or more kinds. One kind of particles have an average particle size of 1 ?m to 50 ?m. Two or more kinds of particles of different particle sizes include nanoscale particles, 10-900 nm. One kind of particles are selected from the group consisting of inorganic compound microspheres. The other kind of particles of the two or more kinds of particles of different particle sizes are selected from the group consisting of organic polymer nanospheres. Also provided is a method for maintaining, culturing and/or differentiating cells using such membrane.

Abstract: Disclosed is a ball float type liquidometer with moving indicator, comprising a ball float chamber and a ferromagnetic spherical ball float provided therein, a moving indicator outside the ball float chamber, a calibrated scale and a moving indicator guide rail, wherein the moving indicator comprises a magnetic steel member, a frame and a rolling system which is horizontally fixed and sheathed in the frame; the rolling system comprises rolling wheels provided with radial grooves along a circumferential surface, rolling bearings and shafts; the magnetic steel member is located between the ball float chamber and the frame and is fixed outside one side face close to the ball float chamber on the frame, and a magnetic pole of the magnetic steel member is directly oriented towards the ball float.

Abstract: Provided is a scalable battery module. In once example embodiment, the module includes a plurality of submodules. Each plurality of submodules is configured to hold one or more cell batteries. The module further includes one or more of a first connector, a second connector, or a third connector. The first connector may secure an alignment of two or more adjacent submodules of the plurality of submodules along a first dimensional axis by using at least one of two slots and two projections of the first connector. The second connector secures the alignment of two adjacent submodules of the plurality of submodules along a second dimensional axis by using at least two further slots of the second connector. The third connector secures the alignment of two adjacent submodules of the plurality of submodules along a third dimensional axis by using at least two further projections of the third connector.

Abstract: Various arrangements for a battery module cooling system are presented. A thermal tower may be contoured to contact one or more battery cells. The thermal tower may include a holding member and a cooling member. A hollow interior region having a top aperture may be defined by the holding member. A portion of each of the one or more battery cells may be contacted by the cooling member to provide localized cooling to each of the one or more battery cells. A seal may be formed between the holding member and the cooling member by positioning the cooling member on the top aperture of the holding member. Optionally, the portion that the cooling members may contact to provide localized cooling may include a hot region having a higher temperature than other portions of each of the one or more battery cells.

Abstract: Apparatuses, systems, and methods of providing electric power to electric vehicles. A housing can have a bottom panel. A battery module can be arranged within the housing. An inlet port and outlet port can be defined through the bottom panel to circulate fluid. A cold plate can be disposed along a bottom surface of the bottom panel. The cold plate can be thermally coupled with the battery module via the bottom panel. The cold plate can have a main intake and a main outtake channel spanning along a top surface to circulate the fluid. The cold plate can a module channel spanning within a module region. The module channel can convey the fluid from the main intake channel to the main outtake channel to transfer heat from the battery module. A sealing element can be arranged along a perimeter region of the top surface to mechanically seal the cold plate.

Abstract: Apparatuses, systems, and methods of providing electric power to components in electric vehicles are detailed herein. A housing can have a bottom panel and side walls defining a cavity. The bottom panel can define an inlet port and an outlet port. A battery module can be disposed within the cavity. A support structure can be on one side wall. The support structure can have a conduit to pass coolant through the housing. A cold plate can be disposed within the cavity and thermally coupled with the battery module. The cold plate can have an inlet, an outlet, and a channel to circulate the coolant from the inlet to the outlet. A distribution plate can be disposed along a bottom surface of the bottom panel. The distribution plate can have a main channel to convey the coolant from the conduit to the cold plate.

Abstract: Apparatuses, systems, and methods to provide electrical power to components in electric vehicles are described herein. A battery pack can be arranged in a first position within an interior opening defined by a lateral member. A connecting member can be coupled with the battery pack, and can have a head and a body. A panel can be disposed along the lateral member, and can have a top and bottom layer. The top layer can define an opening to pass the head and body. The bottom layer can define an opening to support the head. A plate can be disposed on the top layer and can define an opening. The opening of the plate can have a first region to hold the battery pack in the first position and a second region to allow the battery pack to move to a second position outside the interior opening responsive to an impact.

Abstract: Disclosed is a ball float type liquidometer with moving indicator, comprising a ball float chamber and a ferromagnetic spherical ball float provided therein, a moving indicator outside the ball float chamber, a calibrated scale and a moving indicator guide rail, wherein the moving indicator comprises a magnetic steel member, a frame and a rolling system which is horizontally fixed and sheathed in the frame; the rolling system comprises rolling wheels provided with radial grooves along a circumferential surface, rolling bearings and shafts; the magnetic steel member is located between the ball float chamber and the frame and is fixed outside one side face close to the ball float chamber on the frame, and a magnetic pole of the magnetic steel member is directly oriented towards the ball float.