Abstract: A modular microcode (uCode) patch method to support runtime persistent update and associated apparatus. The method enables BIOS uCode patches to be received during platform runtime operations and written to first and second uCode extension regions as uCode images for a firmware device layout that further includes a uCode base region in which a current uCode image is stored. Following a platform reset, the first and second uCode extension regions are inspected to determine if one or more valid and newer uCode images (than the current uCode image) are present. If so, the newest uCode image is booted rather than the current uCode image. Following a successful boot, the newest uCode image is copied to the uCode base region to sync-up the current uCode image to the newest version. In one aspect, received uCode images are written to the first and second uCode extension regions in an alternating manner to support roll-back.

Abstract: A tunnel dynamic blasting device based on geological body intelligent perception, a system and a method are provided. A blasting design instrument body of the tunnel dynamic blasting device is disposed with a 3D laser scanning device, a digital camera device, a borehole locating device, an electronic screen, a built-in computer and a wireless communication device. The 3D laser scanning device, the digital camera device, the borehole locating device, the electronic screen and the wireless communication device are connected to the built-in computer. A housing of the blasting design instrument body is disposed with a battery compartment having a lithium battery secured therein. A range finder is secured above the housing. Problems of non-systematicness and lag of tunnel blasting design and coarseness of borehole locating nowadays are solved, thus the tunnel excavation efficiency and borehole arrangement accuracy in the tunnel cross-section are improved, thereby improving the tunnel blasting quality.

Abstract: It includes updating firmware on a device during operation of the device by: migrating a service executing on the device for execution on a second device; causing the device to enter a disabled state; storing the firmware for access by the device; and causing the device to reset, wherein the device reset comprises the device executing the stored firmware. It can include selecting a device to operate as a boot strap processor, wherein the selected device is one of a group of devices that are to execute the updated firmware and wherein the boot strap processor performs the causing the device to enter a disabled state, storing the firmware for access by the device, and causing the device to reset. The group of devices can comprise a group of threads within a central processing unit (CPU) socket. The group of devices can comprise central processing units (CPUs) within a CPU package.

Abstract: The present invention provides a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound of formula (I), as well as the use and method for preventing or treating FLT3-related conditions, especially conditions related to mutant FLT3 kinase (particularly, FLT3/ITD mutant kinase).

Abstract: A page display method is provided. The method includes determining a first page based on a first operation on a client; and obtaining, in response to the first operation on the client, current scenario information of the client and a first target page set that is generated according to a page jump historical record of the first page. The method also includes determining a second target page set corresponding to the current scenario information according to a correspondence between scenario information and target pages in the first target page set; creating a corresponding page-entry control for at least one page in the second target page set; and displaying the first page and the page-entry control for at least one page.

Abstract: A modular microcode (uCode) patch method to support runtime persistent update and associated apparatus. The method enables BIOS uCode patches to be received during platform runtime operations and written to first and second uCode extension regions as uCode images for a firmware device layout that further includes a uCode base region in which a current uCode image is stored. Following a platform reset, the first and second uCode extension regions are inspected to determine if one or more valid and newer uCode images (than the current uCode image) are present. If so, the newest uCode image is booted rather than the current uCode image. Following a successful boot, the newest uCode image is copied to the uCode base region to sync-up the current uCode image to the newest version. In one aspect, received uCode images are written to the first and second uCode extension regions in an alternating manner to support roll-back.

Abstract: The present invention provides a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound of formula (I), as well as the use and method for preventing or treating FLT3-related conditions, especially conditions related to mutant FLT3 kinase (particularly, FLT3/ITD mutant kinase).

Abstract: A page display method is provided. The method includes determining a first page based on a first operation on a client; and obtaining, in response to the first operation on the client, current scenario information of the client and a first target page set that is generated according to a page jump historical record of the first page. The method also includes determining a second target page set corresponding to the current scenario information according to a correspondence between scenario information and target pages in the first target page set; creating a corresponding page-entry control for at least one page in the second target page set; and displaying the first page and the page-entry control for at least one page.

Abstract: The present application provides a compound of formula I, which is a EGFR and ALK dual inhibitor and can be used alone or in combination with other therapeutic agents to treat diseases such as non-small cell lung cancer. The compounds of the present application are useful in the treatment of diseases carrying the EGFR wild-type gene, or carrying the EGFR T790M mutant gene and/or the EGFR L858R mutant gene and/or the EGFR delE746_A750 mutant gene, or in the treatment of diseases carrying the ALK wild-type gene, ALK F1174L mutant gene and/or ALK F1196M gene and/or EML4-ALK mutant gene and/or NPM-ALK mutant gene, and can be used in the first-line treatment of anaplastic lymphoma kinase (ALK) positive late-stage non-small cell Lung cancer.

Abstract: Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).

Abstract: A mobile-type maintenance square-shaped bin including a bin body, a travelling mechanism provided under the bin body, a car head connected with one end of the bin body, an inlet and an outlet provided at the other end of the bin body, a sealed door provided on the inlet and the outlet, an allocation and transportation device mutually connected with a microcomputer signal provided at a front end of the bin body as well as provided over an internal portion of the bind body, an maintenance platform provided at a bottom of the internal portion of the bin body, a tool platform provided adjacently to the maintenance platform, an ash-removal mechanism provided at an upper portion of the maintenance platform, an air-conditioning device provided at an outer portion of the bin body, and a scanning mechanism provided at a front portion of the maintenance platform.

Abstract: The present application provides a compound of formula I, which is a EGFR and ALK dual inhibitor and can be used alone or in combination with other therapeutic agents to treat diseases such as non-small cell lung cancer. The compounds of the present application are useful in the treatment of diseases carrying the EGFR wild-type gene, or carrying the EGFR T790M mutant gene and/or the EGFR L858R mutant gene and/or the EGFR delE746_A750 mutant gene, or in the treatment of diseases carrying the ALK wild-type gene, ALK F1174L mutant gene and/or ALK F1196M gene and/or EML4-ALK mutant gene and/or NPM-ALK mutant gene, and can be used in the first-line treatment of anaplastic lymphoma kinase (ALK) positive late-stage non-small cell Lung cancer.

Abstract: Provided in the present invention is a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. Also provided in the present invention are a pharmaceutical composition comprising a compound of formula (I) and a use and method for preventing or treating cell proliferative conditions and/or FLT3-related conditions, in particular for conditions responding to the inhibition of FLT3 kinase (especially FLT3/ITD mutant kinases).

Abstract: A mobile-type maintenance square-shaped bin including a bin body, a travelling mechanism provided under the bin body, a car head connected with one end of the bin body, an inlet and an outlet provided at the other end of the bin body, a sealed door provided on the inlet and the outlet, an allocation and transportation device mutually connected with a microcomputer signal provided at a front end of the bin body as well as provided over an internal portion of the bind body, an maintenance platform provided at a bottom of the internal portion of the bin body, a tool platform provided adjacently to the maintenance platform, an ash-removal mechanism provided at an upper portion of the maintenance platform, an air-conditioning device provided at an outer portion of the bin body, and a scanning mechanism provided at a front portion of the maintenance platform.