Patents by Inventor Jiayin Shen

Jiayin Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20220396621
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, coreceptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Application
    Filed: June 22, 2022
    Publication date: December 15, 2022
    Inventors: Chanhyuk KIM, Jun Y. AXUP, Hwayoung YUN, Peter G. SCHULTZ, Jennifer MA, Jiayin SHEN, Pengyu YANG
  • Targeting agent antibody conjugates and uses thereof
    Patent number: 11377496
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: July 5, 2022
    Assignee: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Chanhyuk Kim, Jun Y. Axup, Hwayoung Yun, Peter G. Schultz, Jennifer Ma, Jiayin Shen, Pengyu Yang
  • TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20190315863
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Application
    Filed: May 22, 2019
    Publication date: October 17, 2019
    Inventors: Chanhyuk KIM, Jun Y. AXUP, Hwayoung YUN, Peter G. SCHULTZ, Jennifer MA, Jiayin SHEN, Pengyu YANG
  • Targeting agent antibody conjugates and uses thereof
    Patent number: 10351626
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 16, 2019
    Assignee: The Scripps Research Institute
    Inventors: Chanhyuk Kim, Jun Y. Axup, Hwayoung Yun, Peter G. Schultz, Jennifer Ma, Jiayin Shen, Pengyu Yang
  • ANTI-HUMAN FOLATE RECEPTOR BETA ANTIBODIES AND METHODS OF USE
    Publication number: 20180251544
    Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as method of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Application
    Filed: May 3, 2018
    Publication date: September 6, 2018
    Applicants: PURDUE RESEARCH FOUNDATION, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HE
    Inventors: Philip S. LOW, Dimiter S. DIMITROV, Yang FENG, Jiayin SHEN
  • Anti-human folate receptor beta antibodies and methods of use
    Patent number: 9963505
    Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: May 8, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Philip S. Low, Dimiter S. Dimitrov, Yang Feng, Jiayin Shen
  • Anti-human folate receptor beta antibodies and methods of use
    Patent number: 9914773
    Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: March 13, 2018
    Assignees: PURDUE RESEARCH FOUNDATION, THE UNITED STATES OF AMERICA DEPEARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Philip S. Low, Dimiter S. Dimitrov, Yang Feng, Jiayin Shen
  • TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20170002076
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Application
    Filed: September 16, 2016
    Publication date: January 5, 2017
    Inventors: Chanhyuk KIM, Jun Y. AXUP, Hwayoung YUN, Peter G. SCHULTZ, Jennifer MA, Jiayin SHEN, Pengyu YANG
  • ANTI-HUMAN FOLATE RECEPTOR BETA ANTIBODIES AND METHODS OF USE
    Publication number: 20160207999
    Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Application
    Filed: April 8, 2016
    Publication date: July 21, 2016
    Applicants: PURDUE RESEARCH FOUNDATION, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVI
    Inventors: Philip S. LOW, Dimiter S. DIMITROV, Yang FENG, Jiayin SHEN
  • TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20160115232
    Abstract: Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.
    Type: Application
    Filed: March 14, 2014
    Publication date: April 28, 2016
    Inventors: Chanhyuk KIM, Jun Y. AXUP, Hwayoung YUN, Peter G. SCHULTZ, Jennifer MA, Jiayin SHEN, Pengyu YANG
  • ANTI-HUMAN FOLATE RECEPTOR BETA ANTIBODIES AND METHODS OF USE
    Publication number: 20150110798
    Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Application
    Filed: October 27, 2014
    Publication date: April 23, 2015
    Inventors: Philip S. Low, Dimiter S. Dimitrov, Yang Feng, Jiayin Shen
  • Anti-human folate receptor beta antibodies and methods of use
    Patent number: 8871206
    Abstract: Human anti-human folate receptor beta (FR?) antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: October 28, 2014
    Assignees: Purdue Research Foundation, The United States of America, as Represented by the Secretary Department of Health and Human Services
    Inventors: Philip S. Low, Dimiter S. Dimitrov, Yang Feng, Jiayin Shen
  • ASTHMA IMAGING
    Publication number: 20140271468
    Abstract: The invention relates to methods of imaging asthma using ligand conjugates. More particularly, the invention relates to the use of ligands that bind to cells associated with asthma conjugated to a chromophore, or to a chemical moiety capable of emitting radiation, for administration to a diseased host for imaging asthma.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Purdue Research Foundation
    Inventors: Philip S. Low, Jiayin Shen