Abstract: Use of immune checkpoint inhibitors in combination with anti-aging drugs in tumor treatment and tumor treatment products are disclosed, which provides a new drug and treatment strategy for effective treatment of tumors. The therapeutic effect of the provided treatment of ICIs in combination with the anti-aging drug is superior to that of the current treatment of ICIs treatment alone, and ICIs in combination with chemotherapy, etc. In the action process of ICIs in combination with the anti-aging drug, aging cells can be selectively removed, the aging state of an immune system thus is reversed. Accordingly, the inhibitory effect of tumor on the immune micro-environment is reduced, thus improving the treatment effect on various solid tumors. Based on the use or product provided by the present invention, new strategies and new ideas can be provided for further improving the clinical efficacy and prognosis of the solid tumors.

Abstract: A display may have display layers that form an array of pixels. An angle-of-view adjustment layer may overlap the display layers. The angle-of-view adjustment layer may include an array of adjustable light blocking structures formed from electrochromic material. The electrochromic material may be interposed between first and second electrode layers. When it is desired to operate the display in a private viewing mode, control circuitry may apply a current to the first and second electrodes that causes the electrochromic material to become more opaque, thereby restricting the angle of view of the display. When it is desired to operate the display in a public viewing mode, control circuitry may apply a current to the first and second electrodes that causes the electrochromic material to become more transparent, thereby opening up the angle of view of the display.

Abstract: Provided are a method for inducing differentiated cells into pluripotent endoderm stem cells and an application thereof. Specifically, provided is a method for inducing human differentiated cells to differentiate into induced pluripotent endoderm stem cells (smEnSC), comprising the step of: (a) culturing differentiated cells in a culture system under a first culture condition to obtain induced pluripotent endoderm stem cells (smEnSC), the culture system comprising EGF, A83-01, and CHIR99021. Functional induced pluripotent endodermal stem cells have a high differentiation rate and purity.

Abstract: An electronic device that includes a display and an eye tracker configured to collect eye tracking data regarding a gaze of one or more of a user's eyes across the display is disclosed herein. The electronic device includes processing circuitry that is operatively coupled to the display and configured to foveate one or more areas of the display according to the eye tracking data. If the eye tracking data input is lost, the processing circuitry is configured to recover from the loss of eye tracking data by changing one or more aspects of the foveated areas (e.g., size, resolution, etc.) until a threshold is satisfied. As time elapses since loss of eye tracking, the foveated areas move toward a center or a salient region of the display.

Abstract: An electronic device that includes a display and an eye tracker configured to collect eye tracking data regarding a gaze of one or more of a user's eyes across the display is disclosed herein. The electronic device includes processing circuitry that is operatively coupled to the display and configured to foveate one or more areas of the display according to the eye tracking data. If the eye tracking data input is lost, the processing circuitry is configured to recover from the loss of eye tracking data by changing one or more aspects of the foveated areas (e.g., size, resolution, etc.) until a threshold is satisfied. As time elapses since loss of eye tracking, the foveated areas move toward a center or a salient region of the display.

Abstract: Approaches for presenting user cues based on distance between an electronic device and an object are described. In some examples, content is displayed. First sensor data is received, which is indicative of a first distance between the electronic device and the object. A first version of a user cue relating to the first distance may be presented. Second sensor data is received, which is indicative of a second distance between the electronic device and the object. A second version of the user cue relating to the second distance may be presented.

Abstract: A system may include electronic devices that communicate wirelessly. When positioned so that a pair of devices overlap or are near to one another, the devices may operate in a linked mode. During linked operations, devices may communicate wirelessly while input gathering and content displaying operations are shared among the devices. One or both of a pair of devices may have sensors. An orientation sensor, motion sensor, optical sensor, and/or other sensors may be used in identifying conditions in which to enter the linked mode and to identify a region where displays in the pair of devices overlap.

Abstract: Techniques are provided for implementing near-view notification techniques. In some instances, a viewing distance with respect to a display screen of an electronic device may be determined. In accordance with a determination that the viewing distance is above a distance threshold, content may be presented on the display screen. In accordance with a determination that the viewing distance is under a distance threshold, until the viewing distance returns to being above the distance threshold, a visual notification may be displayed. The visual notification may disrupt the content presented on the display screen.

Abstract: A system may include electronic devices that communicate wirelessly. When positioned so that a pair of devices overlap or are near to one another, the devices may operate in a linked mode. During linked operations, devices may communicate wirelessly while input gathering and content displaying operations are shared among the devices. One or both of a pair of devices may have sensors. An orientation sensor, motion sensor, optical sensor, and/or other sensors may be used in identifying conditions in which to enter the linked mode and to identify a region where displays in the pair of devices overlap.

Abstract: An electronic device such as a cellular telephone or other device may have a housing with front and rear faces joined by a sidewall. A display may be mounted on the front face. The electronic device may include multiple ambient light sensors such as a front ambient light sensor on the front face and one or more supplemental ambient light sensors on the rear face and/or on the sidewall. The front ambient light sensor gathers a front ambient light intensity measurement and the supplemental ambient light sensor gathers a supplemental ambient light intensity measurement. During operation, control circuitry in the electronic device adjusts the display brightness based on data from the ambient light sensors. The control circuitry may implement power saving restrictions that limit when the supplemental ambient light intensity measurement is taken into account and/or that impose a brightness cap on the display brightness.

Abstract: A system may include multiple electronic devices. A first device such as a source electronic device may supply visual content for displaying by a display in a second electronic device such as a display electronic device. The display electronic device may be a television or other device with a display. Calibration operations may be performed by taking light measurements on light produced by the display when test content is provided from the first device to the second device. A third electronic device in the system such as a portable electronic device with an ambient light sensor may make measurement on the light from the display while the test content is being displayed. The test content may contain a test image target with time-varying color and time-varying intensity, allowing calibration information such as gamma curves to be obtained on the display.

Abstract: In some implementations, a mobile computing device may participate in the calibration of an output signal of a media device. This calibration process includes storing device-specific calibration data which is related to properties of a light sensor of the mobile device. The mobile device then detects of properties of light emitted by the display device during a presentation to obtain sensor values related to light emitted by the display device during the presentation. The calibration process may also ensure that the mobile device is proximate to the display device prior to obtaining the sensor values. The collected sensor values are adjusted using device-specific calibration data stored to the mobile device to normalize the sensor values relative to a baseline. These normalized sensor values are sent to the media device for use in adjusting the output signal based on the normalized sensor values.

Abstract: An electronic device such as a cellular telephone or other device may have a housing with front and rear faces joined by a sidewall. A display may be mounted on the front face. The electronic device may include multiple ambient light sensors such as a front ambient light sensor on the front face and one or more supplemental ambient light sensors on the rear face and/or on the sidewall. The front ambient light sensor gathers a front ambient light intensity measurement and the supplemental ambient light sensor gathers a supplemental ambient light intensity measurement. During operation, control circuitry in the electronic device adjusts the display brightness based on data from the ambient light sensors. The control circuitry may implement power saving restrictions that limit when the supplemental ambient light intensity measurement is taken into account and/or that impose a brightness cap on the display brightness.

Abstract: A display may have display layers that form an array of pixels. An angle-of-view adjustment layer may overlap the display layers. The angle-of-view adjustment layer may include an array of adjustable louvers that move from a first position in which the angle of view of the display is restricted for a private viewing mode and a second position in which the angle of view of the display is not restricted for a normal viewing mode. The louvers may contain electrophoretic particles. The louvers may be tapered and may have a width at one end that is less than ten microns. The electrophoretic particles may form isolated clusters on a lower substrate in normal viewing mode to increase the transmittance of the display in normal viewing mode. The angle-of-view adjustment layer may be a second liquid crystal display layer that is used to block off-axis light.

Abstract: In some implementations, a mobile computing device may participate in the calibration of an output signal of a media device. This calibration process includes storing device-specific calibration data which is related to properties of a light sensor of the mobile device. The mobile device then detects of properties of light emitted by the display device during a presentation to obtain sensor values related to light emitted by the display device during the presentation. The calibration process may also ensure that the mobile device is proximate to the display device prior to obtaining the sensor values. The collected sensor values are adjusted using device-specific calibration data stored to the mobile device to normalize the sensor values relative to a baseline. These normalized sensor values are sent to the media device for use in adjusting the output signal based on the normalized sensor values.

Abstract: A tiling display system has multiple display panels. The display panels may be positioned by positioners that are coupled to the display panels. In an untiled operating mode, the display panels of the tiling display system are moved apart. In this mode, each display panel can display different content such as different static images of artwork. In a tiled operating mode, the display panels of the tiling system are moved together to form a single display that displays a single still or moving image. Components on the backs of the display panels and/or along the edges of the display panels may be used to facilitate panel-to-panel alignment, to help couple adjacent panels together, and to support the transfer of power and/or data signals among the panels. The components may include optical and/or electrical alignment sensors, magnets for alignment and coupling, and transmitters and receivers for transmitting and receiving signals.

Abstract: An electronic device that includes a display and an eye tracker configured to collect eye tracking data regarding a gaze of one or more of a user's eyes across the display is disclosed herein. The electronic device includes processing circuitry that is operatively coupled to the display and configured to foveate one or more areas of the display according to the eye tracking data. If the eye tracking data input is lost, the processing circuitry is configured to recover from the loss of eye tracking data by changing one or more aspects of the foveated areas (e.g., size, resolution, etc.) until a threshold is satisfied. As time elapses since loss of eye tracking, the foveated areas move toward a center or a salient region of the display.

Abstract: An electronic device that includes a display and an eye tracker configured to collect eye tracking data regarding a gaze of one or more of a user's eyes across the display is disclosed herein. The electronic device includes processing circuitry that is operatively coupled to the display and configured to foveate one or more areas of the display according to the eye tracking data. If the eye tracking data input is lost, the processing circuitry is configured to recover from the loss of eye tracking data by changing one or more aspects of the foveated areas (e.g., size, resolution, etc.) until a threshold is satisfied. As time elapses since loss of eye tracking, the foveated areas move toward a center or a salient region of the display.

Abstract: An electronic device may include a display that displays virtual reality content. Control circuitry may estimate a brightness adaptation state of a user that is wearing the electronic device. The control circuitry may select a tone mapping curve and brightness level for the virtual reality content based on the user's adaptation state. To estimate the user's adaptation state, the control circuitry may gather ambient light information from an ambient light sensor, may gather physiological attributes of the user such as blink rate, pupil size, and eye openness from a camera, and may gather gaze position information from gaze detection circuitry. The control circuitry may optimize the brightness of the display based on the user's current adaptation state, or the control circuitry may shift the brightness of the display away from the user's adaptation level to help guide the adaptation state to the desired level.

Abstract: In some implementations, a mobile computing device may participate in the calibration of an output signal of a media device. This calibration process includes storing device-specific calibration data which is related to properties of a light sensor of the mobile device. The mobile device then detects of properties of light emitted by the display device during a presentation to obtain sensor values related to light emitted by the display device during the presentation. The calibration process may also ensure that the mobile device is proximate to the display device prior to obtaining the sensor values. The collected sensor values are adjusted using device-specific calibration data stored to the mobile device to normalize the sensor values relative to a baseline. These normalized sensor values are sent to the media device for use in adjusting the output signal based on the normalized sensor values.