Patents by Inventor Jichao Hu

Jichao Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092729
    Abstract: The present invention relates to a method for purifying key intermediates of Citalopram, i.e. 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hydroxymethylbenzonitrile and a salt thereof. The method comprises dissolving crude 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hydroxymethylbenzonitrile (compound of formula I containing formaldehyde impurity) with an organic solvent, adding a washing solution, controlling the temperature, stirring, leaving to stand for layering, and removing the aqueous layer, so as to obtain a purified organic solution of 4-[4-(dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-hydroxymethylbenzonitrile. The method provided by the present invention can effectively remove aldehyde group-containing impurities in the intermediate. The method of the present invention has the advantages of simple operation, cheap raw materials and mild conditions, and is suitable for large-scale industrial production.
    Type: Application
    Filed: December 28, 2021
    Publication date: March 21, 2024
    Applicants: ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD., Zhejiang Huahai LiCheng Pharmaceutical Co., Ltd.
    Inventors: Jian ZHANG, Jichao WANG, Xiangqian YOU, Liangwei QIAN, Tao ZHOU, Jiaxing HU, Wenfeng HUANG
  • Publication number: 20230258377
    Abstract: A refrigeration system and a control method thereof. The refrigeration system includes a compressor and a condenser, and further includes a first throttling device for receiving liquid refrigerant from the condenser; an ejector having a high-pressure fluid inlet, a fluid suction inlet and a fluid outlet, the high-pressure fluid inlet of the ejector is connected to the first throttling device, the fluid outlet of the ejector is connected to a flash tank, a gas-phase outlet of the flash tank is connected to a compressor inlet, a liquid-phase outlet of the flash tank is connected to an evaporator via a second throttling device, and the evaporator is connected to the fluid suction inlet of the ejector; and a controller configured to control an opening of the first throttling device based on a pressure difference between the fluid outlet and the fluid suction inlet of the ejector.
    Type: Application
    Filed: February 7, 2023
    Publication date: August 17, 2023
    Inventors: Hongsheng Liu, Jichao Hu, Xinglei Zhang
  • Publication number: 20190126171
    Abstract: The present invention relates to a gas-liquid separator, including a body enclosing a cavity; a gas outlet attached to the top of the body and communicated with the cavity; a liquid outlet attached to the bottom of the body and communicated with the cavity; and an input tube constructed to include a curve shape extending outside the body and communicated into the cavity from the external of the body. The gas-liquid separator of the present invention has got the advantages of a simple structure, easy manufacturing, convenient mounting, and the like, and can separate a gas-liquid two-phase mixture efficiently, thus providing a purer gas flow and a purer liquid flow for downstream processing apparatuses and improving the overall efficiency of the system.
    Type: Application
    Filed: October 30, 2018
    Publication date: May 2, 2019
    Inventors: Jiaoquan Xu, Qianli Fu, Jichao Hu, Yao Gong, Hongsheng Liu