Patents by Inventor Jidong ZHU

Jidong ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR MODULATING A SRC-1 CONDENSATE
    Publication number: 20240125768
    Abstract: Provided are methods for modulating a SRC-1 condensate to regulate transcription of one or more genes, methods of treating diseases and conditions using SRC-1 inhibitors, and methods for screening of agents that modulate SRC-1 condensate.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 18, 2024
    Applicant: ETERN BIOPHARMA ( SHANGHAI)CO, LTD.
    Inventors: Guangya ZHU, Jingjing XIE, Jidong ZHU, Xin GUO, Hao HE
  • CHIMERIC LYSOZYME VARIANT AND APPLICATION THEREOF IN ANIMAL FEED ADDITIVE
    Publication number: 20240093171
    Abstract: A chimeric lysozyme variant has an improved heat resistance and is encoded by a polynucleotide. A novel chimeric lysozyme sequence is constructed, and high-efficiency expression in a host cell is achieved. The thermal stability of the chimeric lysozyme under the condition of 60° C. is nearly doubled compared to a parental sequence. The chimeric lysozyme variant can be used to prepare product that is antibiotic, for example, animal feed additive containing the chimeric lysozyme variant and an animal feed containing the animal feed additive.
    Type: Application
    Filed: November 12, 2021
    Publication date: March 21, 2024
    Inventors: Fei ZHENG, Ting YAN, Jidong ZHU, Hong XU, Yan SUN, Yanjie LIU
  • THERMOSTABLE GLUCOSE OXIDASE
    Publication number: 20220220454
    Abstract: Provided is a thermostable glucose oxidase obtained by introducing at least one pair of disulfide bonds into an amino acid sequence of a wild-type Aspergillus niger glucose oxidase or a mutant Aspergillus niger glucose oxidase. The glucose oxidase is suitable for application in the fields of food, chemical engineering, medicine, agriculture and feeds.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 14, 2022
    Inventors: Fei Zheng, Ting Yan, Jidong Zhu, Hong Xu, Yan Sun, Aixi Bai
  • Expression of phytase in
    Patent number: 11339397
    Abstract: Disclosed herein is a method for expressing phytase in a filamentous fungus by using an optimized Escherichia coli phytase gene having a nucleotide sequence as shown in SEQ ID NO. 7 and a signal peptide having a nucleotide sequence as shown in SEQ ID NO. 12.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: May 24, 2022
    Assignee: Nanjing Bestzyme Bio-Engineering Co., Ltd.
    Inventors: Aixi Bai, Feng Li, Furong Bian, Jidong Zhu, Yan Sun, Hong Xu
  • 2-Aminopyrimidine Derivative and Preparation Method and Use Thereof
    Publication number: 20210253595
    Abstract: The disclosure provides an aminopyrimidine derivative for preventing and treating diseases related to IDH mutation, a preparation method and use thereof. Specifically, the disclosure provides a compound of Formula I, a stereoisomer, racemate thereof, or pharmaceutically acceptable salt thereof. The compound of the general Formula I has isocitrate dehydrogenase 1 (IDH1) inhibitory activity and can treat cancer induced by IDH1 mutation.
    Type: Application
    Filed: April 25, 2019
    Publication date: August 19, 2021
    Inventors: Jidong ZHU, Hengyi CAO, Lin SUN
  • Indoleamine-2,3-dioxygenase inhibitor and preparation method therefor
    Patent number: 11053207
    Abstract: Disclosed are a compound represented by general formula I and a preparation method therefor. The compound can be used as indoleamine-2,3-dioxygenase inhibitor to prepare medicines for preventing and/or treating indoleamine-2,3-dioxygenase-mediated diseases.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: July 6, 2021
    Assignee: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
    Inventors: Zhaoyin Wang, Wei Guo, Jidong Zhu
  • EXPRESSION OF PHYTASE IN ASPERGILLUS NIGER
    Publication number: 20210032637
    Abstract: Disclosed herein is a method for expressing phytase in a filamentous fungus by using an optimized Escherichia coli phytase gene having a nucleotide sequence as shown in SEQ ID NO. 7 and a signal peptide having a nucleotide sequence as shown in SEQ ID NO. 12.
    Type: Application
    Filed: March 30, 2018
    Publication date: February 4, 2021
    Inventors: Aixi BAI, Feng LI, Furong BIAN, Jidong ZHU, Yan SUN, Hong XU
  • INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20190152932
    Abstract: Disclosed are a compound represented by general formula I and a preparation method therefor. The compound can be used as indoleamine-2,3-dioxygenase inhibitor to prepare medicines for preventing and/or treating indoleamine-2,3-dioxygenase-mediated diseases.
    Type: Application
    Filed: September 15, 2015
    Publication date: May 23, 2019
    Inventors: Zhaoyin WANG, Wei GUO, Jidong ZHU