Abstract: Compounds of formula (I) are described, wherein each of the variable groups is as defined in the specification. Also described are pharmaceutical compositions containing a compound of formula (I), and uses of the compounds and pharmaceutical compositions for inhibiting Nav1.8 voltage-gated sodium channels and treating Nav1.8 mediated diseases, disorders, and conditions, such as pain and pain-associated diseases, disorders, and conditions and cardiovascular diseases, disorders, and conditions, such as atrial fibrillation.

Abstract: Provided are compounds and pharmaceutical compositions and uses thereof for inhibiting Nav1.8 voltage-gated sodium ion channels and treating Nav1.8 mediated diseases, such as pain and pain-associated diseases, and cardiovascular diseases.

Abstract: An electric submersible pump (ESP) assembly. The ESP assembly comprises a first ESP component having a first drive shaft defining a plurality of male splines and defining at least one cut-out area; a second ESP component having a second drive shaft defining a plurality of male splines; a coupling shell defining a first plurality of female splines configured to mate with the male splines of the first drive shaft, a second plurality of female splines configured to mate with the male splines of the second drive shafts, and at least one shouldered aperture configured to align with the cut-out area of the first drive shaft; and at least one removable lug having a pin that is configured to extend through the shouldered aperture in the coupling shell to engage with the at least one cut-out area of the first drive shaft.

Abstract: The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X): wherein Y?, X?, B?, R1?, R2?, R3?, R5?, R6?, R7?, and z1 are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding pharmaceutical compositions or formulations, methods or processes of compound preparation, methods, compounds for use in, uses for and/or combination therapies for treating pain and/or pain-related or associated disease(s), disorder(s) or condition(s), respectively.

Abstract: A complementary metal oxide semiconductor (CMOS) image sensing device includes a semiconductor substrate; a photodiode defined on the substrate; a gate dielectric layer provided over the photodiode and the substrate; a polysilicon interconnect contacting a given area of the photodiode via an opening in the gate dielectric layer; a reset transistor coupled to the photodiode; a source follower transistor coupled to the photodiode; and a select transistor coupled to the source follower transistor. The given area of the photodiode defines a node that is coupled to the reset transistor and source follower transistor.

Abstract: A fan speed control device includes a management selection module, a first and a second buffers, a resistor, a transistor, and a switch. Depending upon whether a motherboard supports a system of a baseboard management control or not, the fan speed control device selectively uses an indicative signal of a serial input and output interface or an indicative signal of the baseboard management control to indicate a power-on status. At the power-on moment, the fan speed control device controls the fan to operate at its minimum speed, so that a system crash due to a power output shortage of a power supply can be avoided. As the system enters stable operation, the fan speed is controlled by a pulse width modulation signal.

Abstract: A fan speed control device includes a management selection module, a first and a second buffers, a resistor, a transistor, and a switch. Depending upon whether a motherboard supports a system of a baseboard management control or not, the fan speed control device selectively uses an indicative signal of a serial input and output interface or an indicative signal of the baseboard management control to indicate a power-on status. At the power-on moment, the fan speed control device controls the fan to operate at its minimum speed, so that a system crash due to a power output shortage of a power supply can be avoided. As the system enters stable operation, the fan speed is controlled by a pulse width modulation signal.