Abstract: A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1 wherein R is —F or —OH, and L2 is linked to R1, R3 or R2, a is an integer of 1 to 10, b, c is each independently an integer of 0 to 10, provided that b and c are not simultaneously 0. R1, R2, and R3, may independently be H, optionally substituted alkyl, or optionally substituted aryl, and R1, may be H or isotope thereof ? C may link R1 and a C linking R2 form a ring.

Abstract: A street greening quality detection method based on physiological activation recognition is provided.

Abstract: The present disclosure provides a method for increasing a number of proteins and/or peptides identified, including: S1. adding a binding buffer and an aluminosilicate zeolite to a sample to be tested to obtain a first suspension; S2. incubating the first suspension, subjecting an incubated first suspension to first high-speed centrifugation to obtain a first supernatant and a first precipitate, discarding the first supernatant, and retaining the first precipitate; S3. repeating a process as follows several times: resuspending the first precipitate with a washing buffer to obtain a second suspension, subjecting the second suspension to second high-speed centrifugation to obtain a second supernatant and a second precipitate, discarding the second supernatant, and retaining the second precipitate; and S4. preparing the second precipitate into a protein sample, and subjecting the protein sample to mass spectrometry detection.

Abstract: Methods of mitigating lipoprotein interference in in vitro diagnostic assays for target hydrophobic analytes are disclosed, as well as compositions, kits, and devices useful in said methods. A pretreatment reagent is utilized that includes at least one enzyme that digests lipoprotein.

Abstract: A method for performing firmware update in an electronic device and a micro control unit equipped with a firmware update function are provided. The method includes: after system reset of the micro control unit, executing an upgrade guiding procedure in an upgrade guiding procedure region by default to start controlling upgrade of a main function procedure in a main function procedure region; checking whether upgrade request information exists, in order to generate a first checking result; in response to the upgrade request information, performing firmware update on multiple sub-regions of the main function procedure region, respectively, to generate an updated main function procedure; performing at least one checking operation to generate at least one checking result; and in response to the at least one checking result, starting executing the updated main function procedure in the main function procedure region.

Abstract: The present disclosure provides a dual-targeting biomimetic liposome with elemene (ELE) and cabazitaxel (CTX), where each 100 mL of the dual-targeting biomimetic liposome with ELE and CTX includes 0.15 g to 0.75 g of the ELE, 0.5 mL to 2.5 mL of absolute ethanol, 0.015 g to 0.07 g of the CTX, 0.25 g to 1 g of oil, 0.25 g to 1 g of a polyethylene glycol (PEG) derivative, 1 g to 5 g of a phospholipid, 0.05 g to 0.2 g of cholesterol, 0.025 g to 0.1 g of distearoyl phosphatidylethanolamine-polyethylene glycol 2000-transferrin (DSPE-PEG2000-Tf), 0.005 g to 0.025 g of a tumor cell membrane protein (CMP), and water as a balance.

Abstract: Methods, systems, and computer programs are presented for parking management and navigation. One method includes operations for determining an availability of a parking space having a parking space ID, obtaining a radio-frequency ID associated with a vehicle occupying the parking space, and communicating the parking space ID and the radio-frequency ID to a storage device via a self-organized network formed by multiple parking space terminals. Further, the method includes operations for providing navigation to a vacant parking space and providing navigation to a parked vehicle.

Abstract: A street greening quality detection method based on physiological activation recognition is provided.

Abstract: A semiconductor device includes a gate structure, a drift region, a source region, a drain region, a first doped region, and a second doped region. The gate structure is over a semiconductor substrate. The drift region is in the semiconductor substrate and laterally extends past a first side of the gate structure. The source region is in the semiconductor substrate and adjacent a second side of the gate structure opposite the first side. The drain region is in the drift region. The first doped region is in the drift region and between the drain region and the gate structure. The second doped region is within the drift region. The second doped region forms a P-N junction with the first doped region at a bottom surface of the first doped region.

Abstract: Systems and methods for enhanced end-to-end three-dimensional (3-D) object detection are disclosed that improve detecting objects in the 3D space from images, such as monocular camera image that may be captured during the operation the autonomous vehicles. For example, a vehicle can include a processor device detecting one or more objects in a 3D space by predicting 3D bounding boxes and predicting dense depth associated with target assignments. The target assignments correspond to the location of objects within an image of the 3D space of a surrounding environment for the vehicle. The vehicle can also include a controller device that receives the detection of the objects in the 3D space from the processor device and performs autonomous operations. The end-to-end 3D object detection techniques achieve a high level of object detection accuracy, with significant improvements compared to previous methods, due to the simplicity and optimization of its end-to-end functionality.

Abstract: A method is provided. The method includes: obtaining a picture to be processed, where the picture to be processed includes a plurality of pixels, and the plurality of pixels comprise first pixels for forming an image and second pixels for forming an image background; rotating the picture to be processed, where for each rotation angle, an intermediate picture is obtained; selecting at least two pictures from the picture to be processed and several intermediate pictures for calculating an area of a bounding box surrounding the image respectively; and removing second pixels outside the bounding box in a picture with the smallest area of bounding box to obtain a processed picture.

Abstract: This application provides a data storage method which is applied to a data storage device and includes: acquiring a first user identification and first user data of a first user; determining, from at least two preset distributed hosts in different areas, a first identification distributed host corresponding to the first user identification and a first data distributed host corresponding to the first user data; sending the first user identification to the first identification distributed host, so that the first identification distributed host stores the first user identification, and generates and stores a first identity identification corresponding to the first user identification; receiving the first identity identification; and sending the first identity identification and the first user data to the first data distributed host, so that the first data distributed host stores them in an associated manner.

Abstract: A device for radar target feature recognition based on optical time-delay fast interference scanning. The device includes an antenna unit, an electro-optical converter, an optical time-delay numerical control scanning device, an optical combiner, a photoelectric detector and a power characteristic analysis device. The device quickly scans the delay amount of the two signals through the optical delay line, and calculates the power of the combined signal through photoelectric conversion and linear power detection. By observing the relationship between the combined power and the delay time, the rapid identification of the target radar signal characteristics is realized.

Abstract: Provided in the present disclosure are anti-P-cadherin antibody-drug conjugates (ADCs) and uses thereof, methods of producing the ADCs as well as methods for validating their functions in vitro and in vivo.

Abstract: A message notification method comprises obtaining, by an ANDROID operating system (OS) running in an ANDROID container, a notification message by monitoring a message processing process of an ANDROID application, sending the notification message to a processor, determining, by the processor and based on an application window associated with the ANDROID application in the notification message, a state of the application window, and displaying in a corresponding manner based on different states of the application window.

Abstract: Systems, methods, and other embodiments described herein relate to improving trajectory forecasting in a device. In one embodiment, a method includes, in response to receiving sensor data about a surrounding environment of the device, identifying an object from the sensor data that is present in the surrounding environment. The method includes determining category probabilities for the object, the category probabilities indicating semantic classes for classifying the object and probabilities that the object belongs to the semantic classes. The method includes forecasting trajectories for the object based, at least in part, on the category probabilities and the sensor data. The method includes controlling the device according to the trajectories.

Abstract: The invention provides a method for continuously producing composite nanoparticles, the method comprising heating a precursor mixture with supercritical water, wherein the mixture contains a first compound capable of transitioning from a monoclinic to a tetragonal rutile crystal state; cooling the heated mixture to obtain core particles of a predetermined shape and size; encapsulating the core particle with a second precursor to create a core-shell construct; and encapsulating the construct with an organic material. Also provided is a device for continuously synthesizing composite nanoparticles, the device comprising a water supply and a precursor supply; a means for heating the water, a continuous flow hydrothermal reaction chamber adapted to receive the heated water and precursor, a means for chilling the heated water and precursor, and a capping agent supply positioned downstream of the reaction chamber.

Abstract: A super junction structure includes a substrate, wherein the substrate has a first conductivity type. The super junction structure includes an epitaxial layer over the substrate, wherein the epitaxial layer has a second conductivity type opposite the first conductivity type. The super junction structure further includes a bury layer between the epitaxial layer and the substrate, wherein the bury layer has the second conductivity type. The super junction structure further includes a conductive pillar in the epitaxial layer, wherein the conductive pillar has the first conductivity type, sidewalls of the conductive pillar are angled with respect to a top-most surface of the epitaxial layer, a bottom surface of the conductive pillar is rounded, and a top-most surface of the conductive pillar is coplanar with the top-most surface of the epitaxial layer.

Abstract: Systems and methods for training multi-view 3D object detection frameworks are disclosed herein. In one example, a method includes the steps of predicting one or more predicted bounding boxes representing one or more objects within multi-view images using a decoder that considers (a) feature embeddings generated from image features from multi-view images, (b) geometric positional encodings that are associated with the feature embeddings, and (c) view-dependent queries, determining a viewpoint equivariance loss based on a comparison of the one or more predicted bounding boxes with one or more ground truth bounding boxes, and adjusting model weights of networks forming the multi-view 3D object detection framework based on the viewpoint equivariance loss.

Abstract: A power decentralized electric locomotive apparatus includes an electric locomotive and a plurality of muck trucks. The electric locomotive and the plurality of muck trucks are connected in sequence, and a mater drive motor is fixedly mounted on the electric locomotive. A slave drive motor is fixedly mounted on at least one of the muck trucks; a torque of the slave drive motor is smaller than a torque of the mater drive motor; and the slave drive motor cooperates with the mater drive motor, to enable the muck truck to travel on rails and reduce drive power and self-weight of the electric locomotive.