Patents by Inventor Jie-Ning Li

Jie-Ning Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of evaluating drug resistance and treatment effect
    Patent number: 11435353
    Abstract: The present invention provides a method of evaluating drug resistance in hormone therapy including the following steps. Firstly, a primary level of TRBP in a subject is measured, and an effective amount of tamoxifen, an active form of tamoxifen or an analogous of tamoxifen is provided to the subject. Then, a level of TRBP in the subject is measured after providing tamoxifen, the active form of tamoxifen or the analogous of tamoxifen. Finally, a level change of TRBP in the subject is discriminated to determine a tamoxifen resistance.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: September 6, 2022
    Assignee: National Cheng Kung University
    Inventors: Pai-Sheng Chen, Jie-Ning Li, Yao-Lung Kuo, Ming-Yang Wang
  • METHOD AND KIT FOR THE EVALUATION OF THE PROGNOSIS OF BREAST CANCER
    Publication number: 20190276895
    Abstract: The present invention provides a method for the detection of the presence of or the risk of breast cancer in a subject is provided. The expression level of snoRNA U50 is detected in a sample isolated from a subject, wherein n decreased expression level of the snoRNA with reference to a normal control indicates the presence of or the risk of breast cancer in the patient from whom the sample was isolated. The present invention further provides a method for predicting the survival time of a patient suffering from a breast cancer and a kit for the detection of the presence of or the risk of breast cancer.
    Type: Application
    Filed: December 6, 2018
    Publication date: September 12, 2019
    Inventors: Pai-Sheng Chen, Jie-Ning Li, Yao-Lung Kuo
  • METHOD OF EVALUATING DRUG RESISTANCE AND TREATMENT EFFECT
    Publication number: 20190277850
    Abstract: The present invention provides a method of evaluating drug resistance in hormone therapy including the following steps. Firstly, a primary level of TRBP in a subject is measured, and an effective amount of tamoxifen, an active form of tamoxifen or an analogous of tamoxifen is provided to the subject. Then, a level of TRBP in the subject is measured after providing tamoxifen, the active form of tamoxifen or the analogous of tamoxifen. Finally, a level change of TRBP in the subject is discriminated to determine a tamoxifen resistance.
    Type: Application
    Filed: December 4, 2018
    Publication date: September 12, 2019
    Inventors: Pai-Sheng Chen, Jie-Ning Li, Yao-Lung Kuo, Ming-Yang Wang