Patents by Inventor Jie Wen Douglas TAY

Jie Wen Douglas TAY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR-BASED METHODS FOR THE DETECTION OF NUCLEIC ACIDS IN A SAMPLE
    Publication number: 20230323439
    Abstract: The present invention is in the field of molecular diagnostics and is directed to the detection of target nucleic acids in a sample using a modified CRISPR-Dx system, typically with prior amplification of the target. The modified CRISPR-Dx system comprising an engineered E174R/S542R/K548R variant of AsCas12a, wherein when get activated indiscriminately cleaves at least one detection reagent to generate signal. In one embodiment, the target nucleic acid is SARS-CoV-2 RNA.
    Type: Application
    Filed: June 25, 2021
    Publication date: October 12, 2023
    Inventors: Meng How TAN, Kean Hean OOI, Jie Wen Douglas TAY, Seok Yee TEO