Patents by Inventor Jieni Xu

Jieni Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS
    Publication number: 20250235411
    Abstract: The present disclosure provides lipid nanoparticle compositions and methods of use. Among other things the present disclosure provides lipid nanoparticle compositions which increased specificity for specific cells or tissues. The present disclosure provides methods of use of the disclosed lipid nanoparticles.
    Type: Application
    Filed: October 14, 2022
    Publication date: July 24, 2025
    Inventors: Thomas Colace, Yusuf Erkul, Jieni Xu, Burak Yilmaz
  • NOVEL DRUG DELIVERY COMPOSITION AND PROCESS FOR BLOOD-BRAIN BARRIER CROSSING
    Publication number: 20220175690
    Abstract: This invention provides polymeric nanoparticles presenting non-conjugated BBB-crossing ligands on their surfaces, compositions and methods of use thereof, as well as non-conjugation methods to produce nanoparticles having BBB-crossing agents on their surfaces.
    Type: Application
    Filed: November 16, 2021
    Publication date: June 9, 2022
    Inventors: Bin Wu, Nicholas Boylan, Zimeng Wang, Jieni Xu
  • NOVEL DRUG DELIVERY COMPOSITION AND PROCESS FOR BLOOD-BRAIN BARRIER CROSSING
    Publication number: 20220175689
    Abstract: This invention provides polymeric nanoparticles presenting non-conjugated BBB-crossing ligands on their surfaces, compositions and methods of use thereof, as well as non-conjugation methods to produce nanoparticles having BBB-crossing agents on their surfaces.
    Type: Application
    Filed: November 16, 2021
    Publication date: June 9, 2022
    Inventors: Bin Wu, Nicholas Boylan, Zimeng Wang, Jieni XU
  • PHARMACEUTICAL COMPOSITION OF SIGLEC-BINDING AGENTS
    Publication number: 20220142935
    Abstract: This invention provides a pharmaceutical composition comprising an agent that can bind Siglec receptors on cell surface. This invention also provides the method of preparing said pharmaceutical composition and the use thereof.
    Type: Application
    Filed: October 5, 2021
    Publication date: May 12, 2022
    Inventors: Bin Wu, Zimeng Wang, Nicholas Boylan, Jieni Xu