Abstract: Smear preparation machine and control method therefor. The smear preparation machine includes a slide loading mechanism for loading slide, a sample applying mechanism for applying blood sample, a slide smearing mechanism for smearing blood sample to prepare smear slide, a staining mechanism and a slide transferring mechanism. The staining mechanism includes a reagent vessel for storing staining reagent and a first driving system for driving the reagent vessel to reciprocally translate in first direction. The slide transferring mechanism includes a manipulator and a second driving system for driving the manipulator to reciprocally translate in second direction. After reagent vessel and manipulator respectively translate to corresponding cooperative positions, the second driving system drives manipulator to move towards reagent vessel to place or remove smear slide in reagent vessel.