Abstract: A portable secure information access system is disclosed. The system comprises a portable storage device and a secure access module. The portable storage device comprises a disk partition, in which a secure information is recorded, particularly in a concealed disk partition, and a secure computing module. The secure computing module generates a session key (SK) in accordance with a challenge-response mechanism. The secure access module receives the SK from the secure computing module, encrypting or decrypting the secure information stored in the disk partition in accordance with the SK so as to access the secure information.